Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   IBL27_RS04690 Genome accession   NZ_CP061071
Coordinates   931538..932845 (+) Length   435 a.a.
NCBI ID   WP_002264510.1    Uniprot ID   -
Organism   Streptococcus mutans B04Sm5     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 926538..937845
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IBL27_RS04670 (IBL27_04670) phoU 926916..927569 (+) 654 WP_002262211.1 phosphate signaling complex protein PhoU -
  IBL27_RS04675 (IBL27_04675) - 927610..930159 (+) 2550 WP_002288091.1 M1 family metallopeptidase -
  IBL27_RS04680 (IBL27_04680) ciaX 930560..930823 (+) 264 WP_002274220.1 three-component system regulator CiaX -
  IBL27_RS04685 (IBL27_04685) ciaR 930874..931548 (+) 675 WP_002264509.1 three-component system response regulator CiaR Regulator
  IBL27_RS04690 (IBL27_04690) ciaH 931538..932845 (+) 1308 WP_002264510.1 three-component system sensor histidine kinase CiaH Regulator
  IBL27_RS04695 (IBL27_04695) rpsT 932934..933188 (-) 255 WP_019321238.1 30S ribosomal protein S20 -
  IBL27_RS04700 (IBL27_04700) coaA 933242..934162 (-) 921 WP_002265491.1 type I pantothenate kinase -
  IBL27_RS04705 (IBL27_04705) - 934258..934854 (+) 597 WP_002308185.1 class I SAM-dependent methyltransferase -
  IBL27_RS04710 (IBL27_04710) - 934963..936240 (+) 1278 WP_002308182.1 pyrimidine-nucleoside phosphorylase -
  IBL27_RS04715 (IBL27_04715) deoC 936259..936921 (+) 663 WP_002262220.1 deoxyribose-phosphate aldolase -
  IBL27_RS04720 (IBL27_04720) - 936827..937297 (+) 471 WP_420801840.1 cytidine deaminase -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 49856.29 Da        Isoelectric Point: 9.7262

>NTDB_id=480249 IBL27_RS04690 WP_002264510.1 931538..932845(+) (ciaH) [Streptococcus mutans B04Sm5]
MLIKLRKQKQDENISFFSHFFAVFTGIFFVMTVIIIQVMHFGIYSSVDNSLKIATENVNDYVNMTLSHNNPITEAENGDA
SFKVKSNGQMAANTDTILYDKKHNVINNVNAFSSLYHIRPKLKDIGDIVEQEAKNIYGQTEKYRTVTVKVNNDFYPQIKF
ATIVINTTQLEEANTRYVTIIISVMIVFWLISVIASVYLAKWSQKPILENYEKQKSFVENASHELRTPLAVLQNRLESLF
RKPEATILDSSESIASSLEEVRNMRMLTANLLNLARRDDGIKPEITEIQPRFFDDTFKNYEMIARENGKKLHITNKVNRQ
IKTDKTLLKQLMTILFDNAVKYTDNDGEIWLDVKTTDRSLIFSVADNGQGISDEDKKKIFDRFYRVDKARTRQKGGFGLG
LSLAKQITDSLKGSIIVKDKKPQGVMFEARLLANK

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=480249 IBL27_RS04690 WP_002264510.1 931538..932845(+) (ciaH) [Streptococcus mutans B04Sm5]
ATGCTAATTAAATTAAGAAAACAAAAGCAGGATGAGAATATTTCATTTTTCAGTCATTTCTTTGCTGTTTTTACCGGAAT
ATTCTTTGTTATGACAGTTATTATTATTCAGGTTATGCATTTTGGTATCTATTCTTCAGTTGATAATAGTCTAAAAATAG
CAACTGAGAATGTCAATGATTATGTCAATATGACTCTATCGCATAATAATCCTATTACTGAAGCTGAAAATGGAGATGCC
TCTTTTAAAGTAAAATCAAATGGCCAGATGGCTGCTAATACAGATACTATTCTTTATGATAAAAAGCATAACGTCATCAA
TAATGTCAATGCCTTCTCTTCTTTGTATCATATTCGCCCTAAACTAAAAGATATTGGTGATATTGTTGAACAAGAAGCTA
AGAATATTTACGGTCAGACCGAAAAGTATCGGACAGTGACAGTTAAGGTAAATAATGACTTTTACCCACAGATAAAATTT
GCAACGATTGTTATTAATACAACACAGCTTGAAGAGGCTAATACGCGTTATGTTACGATTATTATCAGTGTGATGATTGT
TTTTTGGCTTATATCAGTTATTGCCAGTGTTTATTTAGCGAAGTGGAGTCAAAAACCGATTCTGGAAAATTATGAAAAGC
AAAAATCATTTGTTGAAAATGCCAGTCATGAATTACGTACTCCTTTGGCTGTTTTGCAAAATCGCTTGGAGAGTTTGTTT
CGAAAACCAGAGGCTACTATCTTAGATTCTTCGGAATCTATTGCTTCTAGTTTGGAAGAGGTCAGAAACATGAGAATGCT
GACAGCAAATCTCCTTAATTTAGCCCGTCGGGATGATGGTATCAAACCAGAAATAACAGAAATTCAACCTCGTTTTTTTG
ATGATACTTTTAAAAATTATGAGATGATTGCTCGAGAAAATGGGAAAAAATTGCATATTACCAATAAGGTCAACCGTCAA
ATTAAGACAGATAAGACTTTGCTGAAGCAATTAATGACTATTCTTTTTGATAATGCTGTCAAATATACAGATAACGACGG
GGAAATTTGGCTGGACGTCAAGACAACTGATCGCAGTTTAATTTTTTCAGTTGCGGACAATGGTCAAGGTATTTCAGACG
AGGATAAGAAGAAAATTTTTGATCGTTTTTATCGCGTCGATAAAGCCAGAACACGACAAAAGGGTGGGTTCGGACTTGGT
TTGTCTTTGGCAAAACAAATAACAGACAGCTTAAAAGGCAGCATTATTGTTAAAGATAAAAAACCACAAGGAGTAATGTT
TGAAGCTCGCCTGCTTGCTAATAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(215-280)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-431)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

99.77

100

0.998
  ciaH Streptococcus pneumoniae Rx1

55.632

100

0.556
  ciaH Streptococcus pneumoniae D39

55.632

100

0.556
  ciaH Streptococcus pneumoniae R6

55.632

100

0.556
  ciaH Streptococcus pneumoniae TIGR4

55.632

100

0.556