Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   J4Q31_RS10500 Genome accession   NZ_CP071918
Coordinates   1988846..1989862 (-) Length   338 a.a.
NCBI ID   WP_013193332.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 19A-19343     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1983846..1994862
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J4Q31_RS10465 (J4Q31_10465) - 1984256..1984492 (-) 237 WP_001157069.1 hypothetical protein -
  J4Q31_RS11620 - 1984566..1984691 (+) 126 WP_257885839.1 hypothetical protein -
  J4Q31_RS10470 (J4Q31_10475) - 1984684..1984983 (-) 300 WP_191855094.1 hypothetical protein -
  J4Q31_RS10475 (J4Q31_10480) - 1985058..1985333 (-) 276 WP_050202804.1 hypothetical protein -
  J4Q31_RS10480 (J4Q31_10485) - 1985494..1986246 (+) 753 WP_233922969.1 XRE family transcriptional regulator -
  J4Q31_RS10485 (J4Q31_10490) - 1986248..1987012 (+) 765 WP_219576745.1 hypothetical protein -
  J4Q31_RS10490 (J4Q31_10495) - 1987319..1988764 (+) 1446 WP_219576746.1 recombinase family protein -
  J4Q31_RS10500 (J4Q31_10505) comGB/cglB 1988846..1989862 (-) 1017 WP_013193332.1 competence type IV pilus assembly protein ComGB Machinery gene
  J4Q31_RS10505 (J4Q31_10510) comGA/cglA/cilD 1989810..1990751 (-) 942 WP_000249567.1 competence type IV pilus ATPase ComGA Machinery gene
  J4Q31_RS10510 (J4Q31_10515) - 1990827..1991192 (-) 366 WP_000286415.1 DUF1033 family protein -
  J4Q31_RS10515 (J4Q31_10520) - 1991343..1992401 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  J4Q31_RS10520 (J4Q31_10525) nagA 1992564..1993715 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38524.60 Da        Isoelectric Point: 9.6162

>NTDB_id=479508 J4Q31_RS10500 WP_013193332.1 1988846..1989862(-) (comGB/cglB) [Streptococcus pneumoniae strain 19A-19343]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=479508 J4Q31_RS10500 WP_013193332.1 1988846..1989862(-) (comGB/cglB) [Streptococcus pneumoniae strain 19A-19343]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACCATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TAACCCAGATGCGTGTGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTGCTATT
GTCACTCAGTTATCCCTAGCTGAAGTTCATGGCAATCTCCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCCAAGGTCAAGAAAAAATTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGTTTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTTTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

99.112

100

0.991
  comGB/cglB Streptococcus pneumoniae D39

99.112

100

0.991
  comGB/cglB Streptococcus pneumoniae R6

99.112

100

0.991
  comGB/cglB Streptococcus pneumoniae TIGR4

99.112

100

0.991
  comGB/cglB Streptococcus mitis SK321

94.97

100

0.95
  comGB/cglB Streptococcus mitis NCTC 12261

94.379

100

0.944
  comGB Streptococcus gordonii str. Challis substr. CH1

70.833

99.408

0.704
  comGB Streptococcus mutans UA140

58.176

94.083

0.547
  comGB Streptococcus mutans UA159

58.176

94.083

0.547
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503