Detailed information NTG0477207

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: H7792_RS05365
• Genome accession: NZ_CP060643
• Coordinates: 1080262..1081491 (-)
• Length: 409 a.a.
• NCBI ID: WP_228650293.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY416
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1075262..1086491

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7792_RS05345 (H7792_05345)	rpiA	1075543..1076226 (-)	684	WP_011017683.1	ribose-5-phosphate isomerase RpiA	-
H7792_RS05350 (H7792_05350)	-	1076605..1078704 (+)	2100	WP_109991863.1	AAA family ATPase	-
H7792_RS05355 (H7792_05355)	-	1078762..1079505 (-)	744	WP_002984942.1	hypothetical protein	-
H7792_RS05360 (H7792_05360)	yihA	1079653..1080252 (-)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
H7792_RS05365 (H7792_05365)	clpX	1080262..1081491 (-)	1230	WP_228650293.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
H7792_RS05370 (H7792_05370)	-	1081811..1082308 (-)	498	WP_002984955.1	dihydrofolate reductase	-
H7792_RS05375 (H7792_05375)	-	1082388..1083227 (-)	840	WP_011017679.1	thymidylate synthase	-
H7792_RS05380 (H7792_05380)	-	1083436..1084611 (+)	1176	WP_021299369.1	hydroxymethylglutaryl-CoA synthase	-
H7792_RS05385 (H7792_05385)	-	1084598..1085875 (+)	1278	WP_002984963.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45021.46 Da
• Isoelectric Point: 4.5775

>NTDB_id=477207 H7792_RS05365 WP_228650293.1 1080262..1081491(-) (clpX) [Streptococcus pyogenes strain TSPY416]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKATVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=477207 H7792_RS05365 WP_228650293.1 1080262..1081491(-) (clpX) [Streptococcus pyogenes strain TSPY416]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCTCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTCAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGTCGTTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCTCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATCGAAGAAA
CGATGTTAGACATCATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTACTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.753	100	0.888
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575