Detailed information NTG0477103

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: H7795_RS04430
• Genome accession: NZ_CP060641
• Coordinates: 863418..864728 (+)
• Length: 436 a.a.
• NCBI ID: WP_023612943.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY210
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 858418..869728

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7795_RS04415 (H7795_04410)	phoU	859009..859662 (+)	654	WP_002984514.1	phosphate signaling complex protein PhoU	-
H7795_RS04420 (H7795_04415)	-	859867..862404 (+)	2538	WP_023612941.1	M1 family metallopeptidase	-
H7795_RS04425 (H7795_04420)	ciaR	862751..863425 (+)	675	WP_002984519.1	response regulator transcription factor	Regulator
H7795_RS04430 (H7795_04425)	ciaH	863418..864728 (+)	1311	WP_023612943.1	sensor histidine kinase	Regulator
H7795_RS04435 (H7795_04430)	rpsT	864853..865101 (-)	249	WP_009881183.1	30S ribosomal protein S20	-
H7795_RS04440 (H7795_04435)	coaA	865155..866075 (-)	921	WP_023612940.1	type I pantothenate kinase	-
H7795_RS04445 (H7795_04440)	-	866343..866936 (+)	594	WP_010922352.1	class I SAM-dependent methyltransferase	-
H7795_RS04450 (H7795_04445)	-	867589..867978 (+)	390	WP_002984531.1	cytidine deaminase	-
H7795_RS04455 (H7795_04450)	-	868072..869124 (+)	1053	WP_002989701.1	BMP family protein	-

Sequence

Protein

• Length: 436 a.a.
• Molecular weight: 50114.63 Da
• Isoelectric Point: 9.2692

>NTDB_id=477103 H7795_RS04430 WP_023612943.1 863418..864728(+) (ciaH) [Streptococcus pyogenes strain TSPY210]
MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYSSVDSSLVSVSNNASSYANRTMARISSFYFDTENNII
KALPDSDSSKLLGTPAANTDIILFSANGTILNAFDAFSNYQNFHLDKRRLGSIETTSLMNFYGQEEKYHTITVRVHIKNY
PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLTRRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQN
QVNRSLRMDKALLKQLITILFDNAIKYTDKNGIIEIIAKTTDKNLLISVIDNGPGITDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVMSLKGNITVKDNDPKGSIFEVKL

Nucleotide

• Length: 1311 bp

>NTDB_id=477103 H7795_RS04430 WP_023612943.1 863418..864728(+) (ciaH) [Streptococcus pyogenes strain TSPY210]
ATGAATAAATTAAAAAAAGAGATTTTATCAGATAACTATAACCACTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTCATTATGACTATTATTATCTTACAGATTATGCGGTTTGGCGTTTATTCGTCAGTTGATAGTAGTTTAGTTTCTGTTA
GTAATAATGCAAGTAGCTATGCTAATCGTACGATGGCTAGAATATCTTCTTTTTACTTTGATACTGAAAATAACATTATT
AAGGCGCTGCCTGATTCAGATAGTTCTAAGTTATTAGGAACGCCTGCAGCTAATACAGATATCATTTTGTTTAGTGCTAA
TGGAACAATTTTAAATGCTTTTGATGCGTTTTCTAACTATCAAAATTTTCATTTAGATAAACGCCGGTTGGGGAGTATTG
AAACCACCAGTTTAATGAATTTTTATGGACAAGAAGAAAAATACCATACGATAACTGTAAGGGTTCATATCAAAAATTAT
CCTGCAGTTGCCTATATGATGGCAGTAGTAAATGTGGAACAATTAGACCGCGCTAATGAACGTTACGAGCGTATTATTAT
TATAGTTATGAGTGTTTTTTGGCTAATTTCTATTTTAGCAAGTATTTATTTAGCCAAGTGGAGCAGAAAACCTATTTTAG
AAAGCTATGAAAAACAAAAAATGTTTGTTGAAAATGCTAGTCATGAACTAAGGACCCCTTTGGCAGTCTTACAGAATCGT
CTGGAATCGCTTTTTCGTAAGCCCAACGAAACGATATTAGAAAATAGTGAGCATCTCGCTTCTAGTTTAGACGAGGTTCG
CAACATGCGCATCTTAACAACCAATTTATTAAATTTAACAAGACGAGATGATGGCATTAATCCACAGTGGACTCATTTAG
ATACAGATTTTTTTAATGCTATTTTTGAGAATTATGAACTAGTTGCTAAAGAATATGGAAAAATATTTTATTTTCAGAAC
CAAGTCAATAGATCGTTAAGAATGGATAAGGCTTTACTAAAACAATTAATAACGATTTTATTTGACAATGCTATTAAATA
TACAGATAAAAATGGTATTATTGAAATTATAGCGAAAACAACGGACAAAAATTTATTAATTTCTGTTATTGATAATGGTC
CAGGGATAACAGATGAAGAAAAGAAAAAGATTTTTGATCGTTTTTATCGAGTTGACAAAGCTAGAACACGGCAAACAGGT
GGATTTGGCTTGGGGTTGGCTTTAGCTCAGCAAATCGTGATGTCTTTAAAAGGAAATATTACAGTAAAGGATAATGATCC
TAAAGGTAGTATTTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (329-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (220-285)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	57.437	100	0.576
ciaH	Streptococcus pneumoniae Rx1	51.142	100	0.514
ciaH	Streptococcus pneumoniae D39	51.142	100	0.514
ciaH	Streptococcus pneumoniae R6	51.142	100	0.514
ciaH	Streptococcus pneumoniae TIGR4	51.142	100	0.514