Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   JZY07_RS00330 Genome accession   NZ_CP071305
Coordinates   56278..58215 (+) Length   645 a.a.
NCBI ID   WP_024399974.1    Uniprot ID   -
Organism   Streptococcus suis strain SC183     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 51278..63215
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JZY07_RS00315 (JZY07_00315) comR 52044..52961 (+) 918 WP_024399971.1 helix-turn-helix domain-containing protein Regulator
  JZY07_RS00320 (JZY07_00320) - 53226..54446 (+) 1221 WP_024399972.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  JZY07_RS00325 (JZY07_00325) - 54637..56160 (+) 1524 WP_024399973.1 quinol oxidase -
  JZY07_RS00330 (JZY07_00330) hexB 56278..58215 (+) 1938 WP_024399974.1 DNA mismatch repair endonuclease MutL Machinery gene
  JZY07_RS00335 (JZY07_00335) ruvA 58254..58844 (+) 591 WP_024399975.1 Holliday junction branch migration protein RuvA Machinery gene
  JZY07_RS00340 (JZY07_00340) - 58853..59494 (+) 642 WP_024399976.1 hypothetical protein -
  JZY07_RS00345 (JZY07_00345) - 59511..60071 (+) 561 WP_024399977.1 DNA-3-methyladenine glycosylase I -
  JZY07_RS00350 (JZY07_00350) - 60145..60555 (+) 411 WP_024399978.1 helix-turn-helix transcriptional regulator -
  JZY07_RS00355 (JZY07_00355) - 60528..61193 (+) 666 WP_024412038.1 type II CAAX endopeptidase family protein -
  JZY07_RS00360 (JZY07_00360) cinA 61338..62519 (+) 1182 WP_004194467.1 competence/damage-inducible protein A Machinery gene

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72921.13 Da        Isoelectric Point: 5.1152

>NTDB_id=476641 JZY07_RS00330 WP_024399974.1 56278..58215(+) (hexB) [Streptococcus suis strain SC183]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKNQSDLFRIRTLGFRGEALPSIASVSHMIIETATADSAHGLHLEAKGGVIEKEEPVSRPVGTQIAVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFVLVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLKEPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENR
PTSVQFAERQSVESEDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALDLVHKMDALRQVGVNLEEYGANQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=476641 JZY07_RS00330 WP_024399974.1 56278..58215(+) (hexB) [Streptococcus suis strain SC183]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTTAAAA
TGATTCAAATCACGGATAACGGTGAGGGAATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCTACTAGTAAG
ATAAAAAATCAATCGGATTTGTTTCGTATTCGCACCCTCGGTTTTCGTGGAGAAGCTCTGCCTTCCATTGCTTCTGTCAG
TCATATGATCATTGAGACAGCTACGGCAGACTCTGCACACGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCAGTTAGTCGTCCAGTTGGTACGCAGATTGCTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAC
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCCTT
TGTCTTAGTAAACGAAGGGCGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCTGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTATGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCCATTTTCATCAATGGTCGCTATATCAAGAATTTTTTGCTGAATCGAGC
GATTTTGGAAGGTTACGGCAGTAAGTTGATGGTTGGACGCTTTCCGCTGGCAGTCATTTCTATAGAAATCGACCCCTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGTATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCGCTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAAAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGACGTGGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAGA
CCTACATCTGTTCAATTTGCAGAACGTCAGTCGGTGGAATCAGAAGATCAGGAGCATCCTAATCTAAGCGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGGGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAGATGCACGGGA
CGTATTTATTTGCACAAGGCAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAGGTTGACAATTCAGCTCAACAGTTATTGGTGCCCTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTCGTTCACAAAATGGATGCCCTTCGTCAAGTAGGTGTCAACTTAGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAGGAGATTGAGTCTGGCATTTATGAGATGTGCGATATGTTGCTCTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCTATCATGATGTCTTGTAAACGGTCAATCAAGGCCAATCA
TGCTTTGGATGATTATTCGGCGCGTGATTTACTGAGACAATTGTCTTACTGCCAAAATCCCTATAACTGCCCGCACGGCC
GCCCAGTCTTAGTGCATTTTAGCAAGTCAGATATGGAAAAGATGTTCCGTCGCATTCAAGAAAATCACACGAGTTTGCGA
GAATTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(447-589)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.615

100

0.732