Detailed information NTG0047304

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: R2846_RS06735
• Genome accession: NC_017452
• Coordinates: 1404265..1405386 (+)
• Length: 373 a.a.
• NCBI ID: WP_014550983.1
• Uniprot ID: -
• Organism: Haemophilus influenzae R2846
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1399265..1410386

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R2846_RS06720 (R2846_1323)	leuC	1399427..1400836 (-)	1410	WP_014550980.1	3-isopropylmalate dehydratase large subunit	-
R2846_RS06725 (R2846_1324)	leuB	1401012..1402088 (-)	1077	WP_014550981.1	3-isopropylmalate dehydrogenase	-
R2846_RS06730 (R2846_1325)	leuA	1402174..1403721 (-)	1548	WP_014550982.1	2-isopropylmalate synthase	-
R2846_RS06735 (R2846_1326)	dprA	1404265..1405386 (+)	1122	WP_014550983.1	DNA-processing protein DprA	Machinery gene
R2846_RS06740 (R2846_1327)	yaaA	1405439..1406215 (+)	777	WP_005651588.1	peroxide stress protein YaaA	-
R2846_RS06745 (R2846_1328)	-	1406208..1406789 (+)	582	WP_005686250.1	hypothetical protein	-
R2846_RS06750 (R2846_1329)	pfkA	1406885..1407850 (+)	966	WP_014550984.1	6-phosphofructokinase	-
R2846_RS06755 (R2846_1330)	smpB	1408094..1408579 (+)	486	WP_005647965.1	SsrA-binding protein SmpB	-
R2846_RS06760 (R2846_1331)	fis	1408674..1408973 (-)	300	WP_005651583.1	DNA-binding transcriptional regulator Fis	-
R2846_RS06765 (R2846_1332)	dusB	1408967..1409947 (-)	981	WP_014550985.1	tRNA dihydrouridine synthase DusB	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 41699.82 Da
• Isoelectric Point: 6.4124

>NTDB_id=47304 R2846_RS06735 WP_014550983.1 1404265..1405386(+) (dprA) [Haemophilus influenzae R2846]
MNDITYTLLRLMQVPKLGGIGIDKILSNITLNELLNYDDVAFRQMGWGAIQIRRWFKPEAKFIEPALVWSQKEGNHLVNY
FSPFYPFLLKQTANFPPLLFVKGNLTALSQRQMAMVGSRYCTTYGEYWAKHFATELSLAGFTITSGLALGIDGHCHQAVV
NIQGQTIAVLGSGLEQIYPSKHQRLSAQIIENNGALVSEFLPNQAPIAANFPRRNRIISGLSVGTLVVEATEKSGSLITA
RYALEQNREVFAVPGNIQNESSQGCHRLIKQGAMLVENAKDILETLYQHSIHSQTEIDFDQIAVPNYTPPPDPRRLVEAP
SHPKLYSRIGYTPVSIDDLAEEFNLSVDVLLVQLLDLELQDLIMSENGLYKRV

Nucleotide

• Length: 1122 bp

>NTDB_id=47304 R2846_RS06735 WP_014550983.1 1404265..1405386(+) (dprA) [Haemophilus influenzae R2846]
ATGAATGACATTACCTACACATTACTCCGTTTAATGCAAGTGCCTAAACTTGGCGGCATTGGCATTGATAAAATTTTGTC
CAATATTACCTTAAATGAATTACTTAATTATGATGATGTTGCTTTCCGACAAATGGGATGGGGAGCCATTCAAATTCGCC
GTTGGTTCAAACCTGAAGCAAAATTTATTGAGCCAGCACTTGTGTGGTCACAAAAAGAGGGAAATCATTTAGTAAATTAT
TTTTCCCCTTTTTATCCCTTTTTATTGAAACAAACCGCAAACTTTCCGCCACTATTATTTGTAAAAGGAAATTTAACCGC
ACTTTCACAACGCCAAATGGCAATGGTTGGGAGCCGTTATTGCACGACTTATGGAGAATATTGGGCAAAACATTTTGCAA
CAGAACTTTCATTAGCGGGTTTTACCATAACAAGCGGTTTAGCATTAGGAATTGATGGTCATTGTCATCAGGCTGTCGTC
AATATTCAAGGGCAAACTATTGCGGTCTTAGGCAGTGGATTAGAACAAATCTATCCCTCTAAACATCAAAGATTATCAGC
ACAAATCATCGAAAATAATGGGGCATTAGTCTCTGAATTTTTACCTAACCAAGCACCTATTGCTGCTAATTTTCCACGCC
GTAATCGGATTATTAGTGGGCTTTCAGTCGGCACGCTTGTTGTTGAAGCCACCGAAAAAAGTGGATCACTTATTACTGCA
CGGTATGCGTTGGAACAAAACCGAGAGGTTTTTGCTGTGCCAGGCAATATTCAAAATGAATCAAGTCAAGGTTGTCATCG
CCTGATTAAACAAGGCGCAATGTTGGTAGAAAATGCAAAGGACATTTTGGAAACGCTCTACCAACATTCTATCCATAGCC
AAACTGAAATCGATTTTGACCAGATCGCCGTGCCTAATTACACGCCACCACCTGATCCTCGCCGATTAGTAGAAGCACCA
AGCCACCCGAAACTTTATTCGCGTATTGGTTACACGCCAGTGAGCATTGATGATTTAGCGGAAGAATTTAATTTAAGCGT
CGATGTTTTGCTTGTTCAGTTGCTCGATCTTGAGTTGCAAGATCTCATCATGAGTGAAAATGGGTTATATAAACGCGTTT
AG

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (71-277)

• DprA winged helix domain (DprA_WH) (311-367)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Haemophilus influenzae Rd KW20	98.928	100	0.989
dprA	Glaesserella parasuis strain SC1401	52.011	93.298	0.485
dprA	Vibrio campbellii strain DS40M4	43.351	100	0.437
dprA	Vibrio cholerae strain A1552	43.014	97.855	0.421
dprA	Legionella pneumophila strain ERS1305867	40.346	93.029	0.375