Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   R2866_RS00685 Genome accession   NC_017451
Coordinates   138742..139539 (+) Length   265 a.a.
NCBI ID   WP_005649306.1    Uniprot ID   -
Organism   Haemophilus influenzae R2866     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 133742..144539
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R2866_RS00665 (R2866_0132) recR 133916..134518 (-) 603 WP_005626527.1 recombination mediator RecR -
  R2866_RS00670 (R2866_0133) - 134649..134978 (-) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -
  R2866_RS00675 (R2866_0134) - 135131..135976 (-) 846 WP_005666516.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  R2866_RS00680 (R2866_0135) - 136049..138643 (-) 2595 WP_005649307.1 penicillin-binding protein 1A -
  R2866_RS00685 (R2866_0136) comA 138742..139539 (+) 798 WP_005649306.1 pilus assembly protein PilM Machinery gene
  R2866_RS00690 (R2866_0137) comB 139540..140046 (+) 507 WP_005649305.1 competence protein ComB Machinery gene
  R2866_RS00695 (R2866_0138) comC 140043..140564 (+) 522 WP_005649304.1 competence protein ComC Machinery gene
  R2866_RS00700 (R2866_0139) comD 140561..140974 (+) 414 WP_005649303.1 pilus assembly protein PilP Machinery gene
  R2866_RS00705 (R2866_0140) comE 140984..142321 (+) 1338 WP_005649302.1 type IV pilus secretin PilQ family protein Machinery gene
  R2866_RS00710 (R2866_0141) - 142334..143020 (+) 687 WP_005649301.1 ComF family protein -
  R2866_RS00715 (R2866_0142) nfuA 143096..143692 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -

Sequence

Protein


Download         Length: 265 a.a.        Molecular weight: 31541.90 Da        Isoelectric Point: 5.9495

>NTDB_id=47248 R2866_RS00685 WP_005649306.1 138742..139539(+) (comA) [Haemophilus influenzae R2866]
MQFSLKNYRTLQIGIHRKQGYFDFVWFDDLEQPQSYQIFVNDRYFKNRFLQQLKTQYQGKTFPLQFVASIPAHLTWSKVL
MLPQVLNAQECHQQCKFVIEKELPIFLEELWFDYRSTPLKQGFRLEVTAIRQSTAQTYLQDFQPFKINVLDVASNAVLRA
FQYLLNEQVRSENTLFLFQEDDYCLAICERSQQSQILQSHENLTALYEQFTERFEGQLEQVFVYQIPSSHTPLLENWQRV
ETELPFIALGNALWQKDLHQQKVGG

Nucleotide


Download         Length: 798 bp        

>NTDB_id=47248 R2866_RS00685 WP_005649306.1 138742..139539(+) (comA) [Haemophilus influenzae R2866]
ATGCAATTCTCCCTGAAAAATTACCGCACTTTACAAATCGGCATTCATCGTAAGCAGGGTTATTTTGATTTTGTGTGGTT
TGATGATCTTGAGCAGCCACAAAGTTATCAAATCTTTGTTAATGATCGTTATTTTAAAAATCGTTTTTTACAACAGCTAA
AAACACAATATCAAGGGAAAACCTTTCCTTTGCAGTTTGTAGCAAGCATTCCCGCTCACTTAACTTGGTCGAAAGTATTA
ATGTTGCCACAAGTGTTAAATGCGCAAGAATGTCATCAACAATGTAAATTTGTGATTGAAAAAGAGCTGCCTATTTTTTT
AGAAGAATTGTGGTTTGATTATCGTTCTACCCCGTTAAAGCAAGGTTTTCGATTAGAGGTTACTGCAATTCGTCAAAGTA
CTGCTCAAACTTATTTGCAAGATTTTCAGCCATTTAAAATTAATGTATTGGATGTTGCGTCAAATGCTGTTTTGCGTGCA
TTTCAATATCTGTTGAATGAACAAGTGCGGTCAGAAAATACCTTATTTTTATTTCAAGAAGATGACTATTGCTTGGCGAT
TTGTGAAAGATCTCAGCAATCACAAATTTTACAATCTCACGAAAATTTGACCGCACTTTATGAACAATTTACCGAACGTT
TTGAAGGACAACTTGAACAAGTTTTTGTTTATCAAATTCCCTCAAGTCATACACCATTACTAGAAAATTGGCAGCGAGTA
GAAACAGAACTCCCTTTTATTGCACTTGGCAACGCGCTATGGCAAAAAGATTTACATCAACAAAAAGTGGGTGGTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Haemophilus influenzae Rd KW20

97.736

100

0.977
  comA Haemophilus influenzae 86-028NP

96.981

100

0.97

Multiple sequence alignment