Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   I6K87_RS05405 Genome accession   NZ_CP069892
Coordinates   1102409..1103710 (-) Length   433 a.a.
NCBI ID   WP_204982448.1    Uniprot ID   -
Organism   Streptococcus anginosus strain FDAARGOS_1357     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1097409..1108710
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6K87_RS05380 (I6K87_05380) sepM 1098866..1099921 (-) 1056 WP_049533495.1 SepM family pheromone-processing serine protease Regulator
  I6K87_RS05385 (I6K87_05385) coaD 1099902..1100399 (-) 498 WP_049533496.1 pantetheine-phosphate adenylyltransferase -
  I6K87_RS05390 (I6K87_05390) rsmD 1100389..1100937 (-) 549 WP_180363200.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  I6K87_RS05395 (I6K87_05395) hpf 1101127..1101669 (-) 543 WP_204982446.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  I6K87_RS05400 (I6K87_05400) comFC/cflB 1101747..1102412 (-) 666 WP_204982447.1 ComF family protein Machinery gene
  I6K87_RS05405 (I6K87_05405) comFA/cflA 1102409..1103710 (-) 1302 WP_204982448.1 DEAD/DEAH box helicase Machinery gene
  I6K87_RS05410 (I6K87_05410) - 1103767..1104402 (+) 636 WP_204982449.1 YigZ family protein -
  I6K87_RS05415 (I6K87_05415) cysK 1104501..1105430 (+) 930 WP_049533501.1 cysteine synthase A -
  I6K87_RS05420 (I6K87_05420) - 1105832..1106119 (-) 288 Protein_1067 hypothetical protein -
  I6K87_RS05425 (I6K87_05425) dgt 1106353..1107648 (-) 1296 Protein_1068 dGTP triphosphohydrolase -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 48968.69 Da        Isoelectric Point: 8.5388

>NTDB_id=470995 I6K87_RS05405 WP_204982448.1 1102409..1103710(-) (comFA/cflA) [Streptococcus anginosus strain FDAARGOS_1357]
MTELQDCLGRIFTKNQLSPELQLQAQSLAGMVEEKGKLSCNRCGQAIDKEKHQLPIGAYYCRSCLILGRVRSDEELYYFP
QEEFPKANVLKWQGKLTAFQAKVSQGLVEAVTKRKDSLVHAVTGAGKTEMIYQVVAQVINQGGAVCLASPRIDVCLELYR
RLKEDFDCNISLLHGESEAYSRSPLVIATTHQLLKFYRAFDLLIVDEVDAFPYVDNPMLYHAVHQAVKVEGTKIFLTATS
TDELDKKVAKGELTRLSLPRRFHGNPLIVPQKIWLADFQKYLGQKKLVTKLRQFIQKQRKTGFPLLIFASEIRRGQELAE
ILQSNFPNEKVGFVASTTENRLEIVEKFRQKEITILVTTTILERGVTFPCVDVFVVEANHRLFSRSALVQIAGRVGRSTD
RPTGELIFFHDGTTMAIEKAIKEIQEMNQEAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=470995 I6K87_RS05405 WP_204982448.1 1102409..1103710(-) (comFA/cflA) [Streptococcus anginosus strain FDAARGOS_1357]
ATGACGGAATTACAAGATTGTTTAGGTCGCATTTTTACCAAAAATCAACTGTCACCAGAATTGCAATTGCAAGCACAAAG
CTTAGCTGGAATGGTAGAAGAGAAAGGAAAGTTAAGCTGTAATCGCTGTGGACAAGCCATTGACAAAGAAAAACACCAAC
TGCCAATCGGTGCTTATTATTGTAGGTCTTGCTTAATCTTAGGAAGAGTTAGGAGTGATGAAGAACTATACTATTTTCCA
CAGGAAGAATTTCCCAAAGCGAATGTTTTGAAATGGCAAGGAAAGTTGACAGCATTTCAAGCCAAGGTTTCTCAAGGACT
TGTAGAGGCGGTTACCAAACGTAAAGATAGCTTGGTTCACGCAGTCACGGGAGCCGGAAAGACGGAAATGATCTATCAAG
TGGTGGCACAAGTCATCAATCAGGGCGGAGCAGTCTGCTTGGCTAGTCCTAGAATTGATGTCTGCTTAGAACTTTATCGC
AGACTGAAAGAAGATTTTGACTGTAACATTTCACTCCTGCACGGCGAATCAGAAGCATATTCCCGCAGTCCTCTCGTGAT
TGCCACCACACATCAGCTTCTCAAATTTTACCGAGCATTTGATCTTCTTATTGTTGATGAGGTAGATGCCTTTCCTTATG
TGGACAATCCGATGCTTTATCATGCAGTTCATCAGGCAGTCAAAGTAGAGGGGACGAAGATTTTCTTAACAGCAACTTCC
ACAGATGAGCTGGATAAAAAAGTAGCTAAAGGAGAATTAACTCGTTTGAGTCTACCCAGACGTTTTCATGGCAATCCTTT
GATTGTTCCGCAAAAAATTTGGTTGGCGGATTTTCAAAAATATCTTGGTCAAAAGAAGCTAGTTACCAAGTTAAGGCAGT
TTATTCAAAAGCAGAGAAAAACAGGATTTCCACTTCTTATTTTTGCTTCCGAGATCAGAAGAGGGCAGGAGCTGGCAGAG
ATTCTCCAAAGCAATTTTCCAAATGAAAAAGTTGGTTTTGTAGCCTCGACGACTGAAAATCGACTAGAAATTGTAGAGAA
ATTTCGTCAAAAAGAAATCACGATTTTGGTAACGACGACGATTTTGGAGCGTGGGGTGACCTTTCCTTGTGTAGATGTTT
TCGTGGTGGAAGCCAACCACCGTCTGTTTAGTCGCAGCGCTCTGGTACAAATAGCTGGACGAGTCGGTCGCAGTACGGAT
CGACCGACAGGCGAGTTAATCTTTTTTCATGACGGTACAACTATGGCGATAGAAAAAGCGATTAAAGAAATTCAGGAGAT
GAATCAGGAGGCCGGTTTATGA

Domains

Predicted by InterProScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-398)

DEAD/DEAH box helicase (DEAD)

(108-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

71.495

98.845

0.707
  comFA/cflA Streptococcus pneumoniae D39

71.495

98.845

0.707
  comFA/cflA Streptococcus pneumoniae R6

71.495

98.845

0.707
  comFA/cflA Streptococcus pneumoniae TIGR4

71.262

98.845

0.704
  comFA/cflA Streptococcus mitis NCTC 12261

71.362

98.383

0.702
  comFA/cflA Streptococcus mitis SK321

70.892

98.383

0.697
  comFA Lactococcus lactis subsp. cremoris KW2

55.528

91.917

0.51
  comFA Latilactobacillus sakei subsp. sakei 23K

40.835

99.538

0.406
  comFA Bacillus subtilis subsp. subtilis str. 168

39.506

93.533

0.37