Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HP2018_RS00205 Genome accession   NC_017381
Coordinates   37655..38398 (+) Length   247 a.a.
NCBI ID   WP_000660538.1    Uniprot ID   -
Organism   Helicobacter pylori 2018     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 32655..43398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HP2018_RS00180 (hp2018_0038) panD 34804..35157 (+) 354 WP_000142275.1 aspartate 1-decarboxylase -
  HP2018_RS00185 (hp2018_0039) - 35160..35462 (+) 303 WP_000347926.1 YbaB/EbfC family nucleoid-associated protein -
  HP2018_RS00190 (hp2018_0040) - 35462..36466 (+) 1005 WP_000965841.1 PDZ domain-containing protein -
  HP2018_RS00195 (hp2018_0041) comB6 36474..37529 (+) 1056 WP_000679715.1 P-type conjugative transfer protein TrbL Machinery gene
  HP2018_RS00200 (hp2018_0042) comB7 37545..37658 (+) 114 WP_001217877.1 hypothetical protein Machinery gene
  HP2018_RS00205 (hp2018_0043) comB8 37655..38398 (+) 744 WP_000660538.1 type IV secretion system protein Machinery gene
  HP2018_RS00210 (hp2018_0044) comB9 38398..39384 (+) 987 WP_014536255.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HP2018_RS00215 (hp2018_0045) comB10 39377..40507 (+) 1131 WP_001045760.1 DNA type IV secretion system protein ComB10 Machinery gene
  HP2018_RS00220 (hp2018_0046) - 40577..41989 (+) 1413 WP_000694991.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HP2018_RS00225 (hp2018_0047) gmd 42030..43175 (+) 1146 WP_000659866.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28749.97 Da        Isoelectric Point: 8.9604

>NTDB_id=47083 HP2018_RS00205 WP_000660538.1 37655..38398(+) (comB8) [Helicobacter pylori 2018]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYRLLGLMSFIALVLAIVLISILPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKAQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRND

Nucleotide


Download         Length: 744 bp        

>NTDB_id=47083 HP2018_RS00205 WP_000660538.1 37655..38398(+) (comB8) [Helicobacter pylori 2018]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTCGGTTGGAAAGGAATCGCTTGAAAATCGCTT
ACAGGCTTTTAGGTTTGATGAGCTTTATCGCGCTTGTCTTAGCGATCGTTTTAATCAGCATTCTGCCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAATCGCATTGACGATAAATCCCGCT
ATGAACTGGTGCGCTTGCAAAGCAGCTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAGCCCAAAACAGCATCTAT
GCGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCCATTGCGGCTAAACTTTTGAATGAAAACAAGCTCGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCACCGACTAATAGGAATGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.761

100

0.968

Multiple sequence alignment