Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   H3L95_RS12765 Genome accession   NZ_CP059566
Coordinates   2692970..2693833 (-) Length   287 a.a.
NCBI ID   WP_003757133.1    Uniprot ID   C6M3E3
Organism   Neisseria sicca strain DSM 17713     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2687970..2698833
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H3L95_RS12740 (H3L95_12740) - 2689505..2690371 (-) 867 WP_003757139.1 hypothetical protein -
  H3L95_RS12745 (H3L95_12745) - 2690404..2691255 (-) 852 WP_003757138.1 mechanosensitive ion channel family protein -
  H3L95_RS12750 (H3L95_12750) - 2691559..2691894 (+) 336 WP_003757137.1 hypothetical protein -
  H3L95_RS12755 (H3L95_12755) yacG 2692099..2692284 (-) 186 WP_040668227.1 DNA gyrase inhibitor YacG -
  H3L95_RS12760 (H3L95_12760) coaE 2692339..2692968 (-) 630 WP_003757134.1 dephospho-CoA kinase -
  H3L95_RS12765 (H3L95_12765) pilD 2692970..2693833 (-) 864 WP_003757133.1 A24 family peptidase Machinery gene
  H3L95_RS12770 (H3L95_12770) pilG 2693835..2695076 (-) 1242 WP_003757131.1 type II secretion system F family protein Machinery gene
  H3L95_RS12775 (H3L95_12775) pilF 2695148..2696827 (-) 1680 WP_003757129.1 type IV-A pilus assembly ATPase PilB Machinery gene
  H3L95_RS12780 (H3L95_12780) - 2697352..2697825 (-) 474 WP_003757128.1 outer membrane protein assembly factor BamE -

Sequence

Protein


Download         Length: 287 a.a.        Molecular weight: 31441.75 Da        Isoelectric Point: 8.3248

>NTDB_id=470755 H3L95_RS12765 WP_003757133.1 2692970..2693833(-) (pilD) [Neisseria sicca strain DSM 17713]
MLESLDTLAPFAIPLSVVVGLLIGSFLNVVIYRVPVMMERGWTQFAKEHLQLELTEEEQQPFNLMKPDSRCPKCHAPVKA
WQNIPIFSYLMLGGKCGSCKTPISIRYPLIELLTGILFGVMAWQYGWTMAAFGGLILTALLIALTFIDADTQYLPDSLTL
PLIWLGLLFNLNGTFVPLKSAVLGAVFGYMSLWLLCFIYKLLTGKIGMGNGDFKLLAALGAWLGVGILPVLVFMAALIGL
IGAIIGRVAKGQYFAFGPSLAIAGWIILVANEPVHRAVTWWLTKSGF

Nucleotide


Download         Length: 864 bp        

>NTDB_id=470755 H3L95_RS12765 WP_003757133.1 2692970..2693833(-) (pilD) [Neisseria sicca strain DSM 17713]
ATGCTGGAATCTTTGGATACATTAGCACCATTTGCTATTCCATTATCTGTCGTCGTTGGTTTGTTAATCGGAAGTTTCCT
TAATGTTGTCATTTACCGCGTTCCTGTTATGATGGAACGCGGCTGGACTCAGTTTGCGAAAGAGCATTTGCAGCTTGAAT
TAACGGAAGAAGAGCAGCAACCATTCAATTTGATGAAACCGGATTCACGCTGCCCTAAGTGTCATGCCCCGGTAAAGGCT
TGGCAAAATATTCCGATTTTCAGTTATCTGATGCTTGGTGGTAAATGTGGTTCGTGTAAAACGCCCATCAGCATCCGTTA
TCCCTTAATCGAATTATTGACCGGCATATTGTTTGGTGTTATGGCGTGGCAATATGGCTGGACGATGGCTGCATTTGGCG
GTTTGATATTGACTGCGCTATTGATTGCATTGACCTTTATCGATGCAGATACTCAATATTTACCTGACAGCCTGACCCTG
CCGCTGATATGGTTAGGCTTGCTGTTTAATTTGAATGGCACTTTTGTTCCATTAAAATCTGCCGTTTTAGGCGCGGTTTT
CGGCTATATGAGCTTATGGCTGTTGTGTTTTATCTATAAGCTTTTGACTGGAAAAATCGGTATGGGTAACGGCGATTTTA
AATTGCTGGCTGCACTAGGTGCATGGCTTGGTGTCGGCATTTTACCTGTATTGGTCTTTATGGCAGCTTTAATTGGTCTG
ATTGGTGCGATTATCGGACGGGTTGCCAAAGGACAATATTTTGCATTCGGTCCGAGTTTGGCTATTGCCGGCTGGATTAT
TTTGGTAGCTAATGAGCCGGTACATCGTGCCGTCACTTGGTGGCTGACCAAATCAGGGTTTTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(135-241)

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(18-125)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C6M3E3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

73.498

98.606

0.725
  pilD Vibrio cholerae strain A1552

47.636

95.819

0.456
  pilD Acinetobacter nosocomialis M2

49.042

90.941

0.446
  pilD Acinetobacter baumannii D1279779

48.659

90.941

0.443
  pilD Vibrio campbellii strain DS40M4

44.364

95.819

0.425