Detailed information NTG0470242

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: H2N97_RS17875
• Genome accession: NZ_CP059497
• Coordinates: 3595564..3596727 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain JSRB 08
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3590564..3601727

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H2N97_RS17845 (H2N97_17845)	-	3590829..3591248 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
H2N97_RS17850 (H2N97_17850)	comFC	3591322..3592011 (-)	690	WP_217425079.1	phosphoribosyltransferase family protein	Machinery gene
H2N97_RS17855 (H2N97_17855)	-	3592017..3592301 (-)	285	WP_017418816.1	late competence development ComFB family protein	-
H2N97_RS17860 (H2N97_17860)	comFA	3592359..3593744 (-)	1386	WP_134986672.1	DEAD/DEAH box helicase	Machinery gene
H2N97_RS17865 (H2N97_17865)	-	3593852..3594700 (-)	849	WP_015418336.1	DegV family protein	-
H2N97_RS17870 (H2N97_17870)	degU	3594798..3595487 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
H2N97_RS17875 (H2N97_17875)	degS	3595564..3596727 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
H2N97_RS17880 (H2N97_17880)	-	3596950..3597597 (+)	648	WP_007614107.1	YigZ family protein	-
H2N97_RS17885 (H2N97_17885)	-	3597602..3598795 (+)	1194	WP_017418814.1	LCP family protein	-
H2N97_RS17890 (H2N97_17890)	-	3598895..3599971 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
H2N97_RS17895 (H2N97_17895)	-	3600103..3601299 (-)	1197	WP_017418813.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=470242 H2N97_RS17875 WP_007407484.1 3595564..3596727(-) (degS) [Bacillus velezensis strain JSRB 08]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=470242 H2N97_RS17875 WP_007407484.1 3595564..3596727(-) (degS) [Bacillus velezensis strain JSRB 08]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGAAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCAGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGCCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGATAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951