Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   H1R75_RS08120 Genome accession   NZ_CP059471
Coordinates   1598038..1598730 (-) Length   230 a.a.
NCBI ID   WP_021143010.1    Uniprot ID   A0A239R7J1
Organism   Streptococcus equinus strain MDC1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1593038..1603730
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1R75_RS08100 (H1R75_08100) dnaI 1593847..1594749 (-) 903 WP_024343628.1 primosomal protein DnaI -
  H1R75_RS08105 (H1R75_08105) - 1594760..1595911 (-) 1152 WP_033153205.1 DnaD domain protein -
  H1R75_RS08110 (H1R75_08110) nrdR 1595898..1596392 (-) 495 WP_004233042.1 transcriptional regulator NrdR -
  H1R75_RS08115 (H1R75_08115) - 1596551..1597933 (-) 1383 WP_235686230.1 ATP-binding protein -
  H1R75_RS08120 (H1R75_08120) covR 1598038..1598730 (-) 693 WP_021143010.1 response regulator transcription factor Regulator
  H1R75_RS08125 (H1R75_08125) - 1598971..1599507 (-) 537 WP_024343625.1 YceD family protein -
  H1R75_RS08130 (H1R75_08130) htpX 1599656..1600555 (-) 900 WP_024343624.1 zinc metalloprotease HtpX -
  H1R75_RS08135 (H1R75_08135) - 1600672..1601223 (-) 552 WP_021143013.1 LemA family protein -
  H1R75_RS08140 (H1R75_08140) rsmG 1601518..1602231 (+) 714 WP_182001337.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  H1R75_RS08145 (H1R75_08145) - 1602297..1603669 (+) 1373 Protein_1548 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26437.38 Da        Isoelectric Point: 4.8639

>NTDB_id=469845 H1R75_RS08120 WP_021143010.1 1598038..1598730(-) (covR) [Streptococcus equinus strain MDC1]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVETNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKETSIIMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQEANSKHDKEGQAKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLASVWRYDTDIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=469845 H1R75_RS08120 WP_021143010.1 1598038..1598730(-) (covR) [Streptococcus equinus strain MDC1]
ATGAGTAAAAAGATTTTAATTATTGAGGATGAAAAAAATCTTGCACGCTTCGTGTCTTTGGAGTTACAACACGAAGGGTA
TTCAGTAGTTGTTGAGACAAATGGGCGTTTAGGTTTACAAACGGCTTTAGATGATGATTTTGATTTGATCCTGTTAGATT
TGATGTTGCCTGATATGGATGGATTCGAAATTACACGTCGTCTTCGTCTGGAAAAAGAAACTTCAATTATCATGATGACA
GCTCGTGATTCAATCATGGATATCGTTGCTGGTCTTGATCGTGGTGCAGATGATTACATCGTAAAACCATTTGCTATTGA
AGAATTACTAGCGCGTGTGCGTGCAGTGTTCCGTCGTCAAGAAGCTAATTCTAAACATGATAAAGAAGGCCAAGCAAAAG
AGGGGTTGCTAGGACTTCGTCTTAATCCACAAAATCGTTCTGCAGTTCGTGGAGACGATGAAATTTCATTAACAAAACGC
GAATATGATTTGTTAAGTGTTCTTCTTTCAAACGTTAACCGAGTGATGACACGTGAAGAATTACTTGCAAGTGTTTGGCG
TTATGATACTGATATCGAAACAAACGTAGTGGATGTTTACATCCGTTATCTTCGTGGAAAAATTGATATTCCTGGTAAAG
AATCATATATCCAAACTGTTCGTGGAATGGGTTATATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A239R7J1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

75.217

100

0.752
  covR Lactococcus lactis subsp. lactis strain DGCC12653

65.066

99.565

0.648
  vicR Streptococcus mutans UA159

41.991

100

0.422
  micA Streptococcus pneumoniae Cp1015

41.739

100

0.417