Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FOLKNPGA_RS14050 Genome accession   NZ_CP059400
Coordinates   3216047..3216706 (-) Length   219 a.a.
NCBI ID   WP_182350482.1    Uniprot ID   A0A7G4A3D5
Organism   Legionella sp. PC1000     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3211047..3221706
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOLKNPGA_RS14035 (FOLKNPGA_02850) - 3212371..3212943 (-) 573 WP_182352875.1 endopeptidase IV -
  FOLKNPGA_RS14040 (FOLKNPGA_02851) - 3212951..3213661 (-) 711 WP_182350480.1 L,D-transpeptidase -
  FOLKNPGA_RS14045 (FOLKNPGA_02853) uvrC 3213920..3215782 (-) 1863 WP_182350481.1 excinuclease ABC subunit UvrC -
  FOLKNPGA_RS14050 (FOLKNPGA_02854) letA 3216047..3216706 (-) 660 WP_182350482.1 two-component system response regulator LetA Regulator
  FOLKNPGA_RS14055 (FOLKNPGA_02855) phhA 3216794..3217612 (-) 819 WP_182350483.1 phenylalanine 4-monooxygenase -
  FOLKNPGA_RS14060 (FOLKNPGA_02856) - 3217785..3218879 (+) 1095 WP_182350484.1 molybdopterin-binding protein -
  FOLKNPGA_RS14065 (FOLKNPGA_02857) cgtA 3218835..3219860 (-) 1026 WP_182350485.1 Obg family GTPase CgtA -
  FOLKNPGA_RS14070 (FOLKNPGA_02858) rpmA 3220006..3220284 (-) 279 WP_058521330.1 50S ribosomal protein L27 -
  FOLKNPGA_RS14075 (FOLKNPGA_02859) rplU 3220297..3220608 (-) 312 WP_058521331.1 50S ribosomal protein L21 -
  FOLKNPGA_RS14080 (FOLKNPGA_02860) - 3220883..3221548 (+) 666 WP_182350486.1 50S ribosomal protein L25/general stress protein Ctc -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24341.37 Da        Isoelectric Point: 5.0144

>NTDB_id=469392 FOLKNPGA_RS14050 WP_182350482.1 3216047..3216706(-) (letA) [Legionella sp. PC1000]
MIKVLIVDDHALVRMGIRRLLEDMSDVEVVADAESGEQALALVKKYSPDVVLLDMKMPGIDGWEVTRRLKKSNPHIKVIA
VTAMCSDVLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKVAINSLEEVQGSPFDVLSEREMQVMLMI
TSGMNVQEISDRLFLSTKTINGYRYRTFEKLGIKNDVELTYLALKHGIIENPIDLASED

Nucleotide


Download         Length: 660 bp        

>NTDB_id=469392 FOLKNPGA_RS14050 WP_182350482.1 3216047..3216706(-) (letA) [Legionella sp. PC1000]
TTGATTAAAGTACTAATTGTTGATGACCATGCATTGGTTCGAATGGGGATTCGACGATTACTCGAAGATATGTCAGATGT
AGAGGTAGTCGCTGATGCAGAAAGTGGTGAGCAAGCTTTAGCATTAGTAAAAAAATACTCCCCAGATGTAGTTCTTTTAG
ATATGAAAATGCCTGGAATCGATGGGTGGGAAGTAACGCGTCGCCTGAAAAAATCAAATCCGCATATTAAAGTAATCGCT
GTAACTGCGATGTGTTCCGATGTGTTGCCTACCCGTGTTTTGCAATTAGGGGCTATGGGATATCTGACGAAAGAATCGGG
TGCCGAAGAAATGGCTGCTGCAATCCGTAAAGTAGCGAAAGGAGAAAAGTACCTTAGTGCCGAAATCGCTCAGAAAGTAG
CGATTAATAGTTTAGAGGAGGTACAAGGTTCGCCTTTTGATGTGTTATCTGAGCGTGAAATGCAAGTGATGTTGATGATT
ACCAGCGGCATGAATGTTCAGGAAATTAGTGATAGACTTTTCCTAAGCACAAAAACAATTAACGGTTATCGTTATCGAAC
ATTTGAAAAATTAGGCATTAAAAATGATGTGGAGCTCACTTATCTGGCTCTAAAACACGGAATTATAGAAAATCCCATCG
ATCTGGCATCAGAGGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7G4A3D5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

89.041

100

0.89
  letA Legionella pneumophila strain ERS1305867

89.041

100

0.89