Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/comE1   Type   Machinery gene
Locus tag   H1C99_RS12245 Genome accession   NZ_CP059331
Coordinates   2488927..2489265 (+) Length   112 a.a.
NCBI ID   WP_006251644.1    Uniprot ID   A0A248ZWT2
Organism   Mannheimia haemolytica strain 0597     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2483927..2494265
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1C99_RS12215 (H1C99_12205) rpsL 2484215..2484589 (-) 375 WP_005543325.1 30S ribosomal protein S12 -
  H1C99_RS12220 (H1C99_12210) rfaC 2484710..2485669 (-) 960 WP_240030059.1 lipopolysaccharide heptosyltransferase RfaC -
  H1C99_RS12225 (H1C99_12215) waaF 2485735..2486772 (-) 1038 WP_020824266.1 lipopolysaccharide heptosyltransferase II -
  H1C99_RS12230 - 2486883..2487044 (-) 162 WP_240030060.1 hypothetical protein -
  H1C99_RS12235 - 2487063..2487299 (-) 237 WP_240030061.1 hypothetical protein -
  H1C99_RS12240 (H1C99_12225) - 2487359..2488633 (-) 1275 WP_240026935.1 LysM-like peptidoglycan-binding domain-containing protein -
  H1C99_RS12245 (H1C99_12230) comEA/comE1 2488927..2489265 (+) 339 WP_006251644.1 ComEA family DNA-binding protein Machinery gene
  H1C99_RS12250 (H1C99_12235) asd 2489429..2490325 (+) 897 WP_240030062.1 archaetidylserine decarboxylase -
  H1C99_RS12255 (H1C99_12240) - 2490397..2492751 (+) 2355 WP_240030063.1 DEAD/DEAH box helicase family protein -

Sequence

Protein


Download         Length: 112 a.a.        Molecular weight: 12111.91 Da        Isoelectric Point: 10.0993

>NTDB_id=468780 H1C99_RS12245 WP_006251644.1 2488927..2489265(+) (comEA/comE1) [Mannheimia haemolytica strain 0597]
MKKIKQLGLTFLFGLNAMAFAQTPPTTMPVEQNAVTQPVQQTQITNANAVNINTASAAELQDKLVGIGQKKAQAIVDYRT
KNGNFKNIEQLAEVSGIGQATVEKNRANIILE

Nucleotide


Download         Length: 339 bp        

>NTDB_id=468780 H1C99_RS12245 WP_006251644.1 2488927..2489265(+) (comEA/comE1) [Mannheimia haemolytica strain 0597]
ATGAAGAAAATCAAACAACTTGGTCTAACATTCTTGTTTGGCTTAAATGCAATGGCTTTTGCCCAAACACCGCCAACTAC
AATGCCTGTTGAACAAAATGCAGTCACTCAACCCGTACAGCAAACACAAATCACCAACGCCAATGCGGTAAATATCAATA
CTGCTAGTGCTGCTGAATTGCAAGACAAGCTAGTGGGAATTGGGCAGAAAAAAGCTCAAGCGATTGTCGATTACCGTACT
AAAAACGGCAATTTTAAAAACATTGAGCAACTTGCTGAAGTCTCCGGAATTGGGCAAGCAACGGTAGAAAAAAATCGAGC
CAATATTATTTTAGAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(46-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A248ZWT2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/comE1 Glaesserella parasuis strain SC1401

59.292

100

0.598
  comE1/comEA Haemophilus influenzae Rd KW20

52.747

81.25

0.429
  comEA Vibrio cholerae C6706

54.651

76.786

0.42
  comEA Vibrio cholerae strain A1552

54.651

76.786

0.42