Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HS074_RS09565 Genome accession   NZ_CP059245
Coordinates   1887285..1888484 (+) Length   399 a.a.
NCBI ID   WP_409038310.1    Uniprot ID   -
Organism   Mannheimia haemolytica strain 0740     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1882285..1893484
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HS074_RS09535 (HS074_09460) proB 1882683..1883768 (-) 1086 WP_409037686.1 glutamate 5-kinase -
  HS074_RS09540 (HS074_09465) folA 1883880..1884374 (+) 495 WP_006248397.1 type 3 dihydrofolate reductase -
  HS074_RS09545 (HS074_09470) - 1884493..1884723 (+) 231 WP_006248398.1 YgjV family protein -
  HS074_RS09550 (HS074_09475) radA 1884778..1886157 (-) 1380 WP_240019414.1 DNA repair protein RadA -
  HS074_RS09555 (HS074_09480) pilA 1886336..1886815 (+) 480 WP_006248401.1 prepilin peptidase-dependent pilin Machinery gene
  HS074_RS09560 (HS074_09485) - 1886836..1887279 (+) 444 Protein_1837 pilus assembly protein PilB -
  HS074_RS09565 (HS074_09490) pilC 1887285..1888484 (+) 1200 WP_409038310.1 type II secretion system F family protein Machinery gene
  HS074_RS09570 - 1888487..1888690 (+) 204 WP_240019416.1 hypothetical protein -
  HS074_RS09575 - 1888762..1888968 (+) 207 Protein_1840 peptidase A24 -
  HS074_RS09580 (HS074_09500) coaE 1889182..1889817 (+) 636 WP_409038838.1 dephospho-CoA kinase -
  HS074_RS09585 (HS074_09505) yacG 1889799..1889984 (+) 186 WP_006248406.1 DNA gyrase inhibitor YacG -
  HS074_RS09590 (HS074_09510) holA 1889985..1891010 (-) 1026 WP_409038839.1 DNA polymerase III subunit delta -
  HS074_RS09595 (HS074_09515) lptE 1891053..1891541 (-) 489 WP_409038311.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 399 a.a.        Molecular weight: 45277.35 Da        Isoelectric Point: 9.4698

>NTDB_id=468152 HS074_RS09565 WP_409038310.1 1887285..1888484(+) (pilC) [Mannheimia haemolytica strain 0740]
MTKIYEFHWQAQSRFGQKQRGKRLATNRDMLENLLLAQGYQHIRISRNFVLSANPKKEEVNSLLSQLALLVNSAMPLKQA
LSMLLQNCRNIRLYLWLNELIQHIESGYAFSQSLEKLGEFVTNQEIQLIKMGEQSGKLGIMLTNLAESRAKLEKLAKKVK
KILFYPVIVLLISLALSIGLLVLIVPQFAQLYGSXKDKTLPLITDILFTLSECLIEQGTVLLGTLLLAVIFYLXFAKKSR
LVAKWKMALWAKMPLFSRIIEQSRIIFFSQNIALMLNAHIPLDVALRSFLSEKNDDPILQQEIGTMLNLLQQGYKFSQGI
NPNVFGAEMAQMLEVGEKSGNVAKMCEHISEMYQQKLDYQIDILSQLLEPMLMLIMGVIVGTIIVGLYLPIFDMGALVE

Nucleotide


Download         Length: 1200 bp        

>NTDB_id=468152 HS074_RS09565 WP_409038310.1 1887285..1888484(+) (pilC) [Mannheimia haemolytica strain 0740]
ATGACGAAAATCTATGAATTTCATTGGCAAGCCCAGAGCCGATTTGGGCAAAAACAGCGGGGCAAGCGGTTGGCAACGAA
TCGAGACATGTTGGAAAACCTTTTGCTGGCACAAGGTTATCAGCATATTCGGATTAGCCGAAATTTTGTGCTTTCAGCAA
ACCCGAAAAAAGAAGAGGTGAATAGCTTGCTATCACAGCTTGCATTGTTGGTTAATTCTGCCATGCCGTTAAAACAGGCA
TTATCTATGTTGTTGCAAAACTGCCGAAATATCCGCCTTTATCTATGGCTTAATGAGCTGATTCAGCATATTGAAAGTGG
CTATGCTTTTTCACAATCGTTGGAGAAATTGGGTGAATTTGTGACCAATCAGGAAATTCAGCTAATCAAAATGGGCGAAC
AAAGCGGAAAACTGGGCATTATGCTGACTAATTTAGCTGAAAGCCGAGCGAAATTGGAAAAATTGGCGAAAAAAGTGAAG
AAAATCCTGTTTTACCCGGTGATTGTGTTGCTGATTTCGCTCGCTTTATCTATCGGGCTATTGGTTTTGATTGTACCGCA
GTTTGCCCAACTTTATGGCTCANNAAAAGACAAAACTTTACCCCTCATTACCGATATTTTATTTACCCTTTCCGAATGCT
TGATTGAGCAAGGCACAGTATTACTTGGCACGTTACTACTAGCGGTCATTTTTTACCTGTTNTTTGCNAAAAAGAGCAGG
TTAGTCGCAAAGTGGAAAATGGCTCTATGGGCTAAAATGCCACTGTTTAGCCGAATTATTGAGCAATCTCGCATTATCTT
TTTCAGCCAAAATATTGCCTTAATGCTGAATGCTCATATTCCGCTTGATGTTGCCTTGAGGTCGTTTTTATCCGAGAAAA
ATGATGACCCGATTTTACAGCAAGAAATTGGCACTATGCTTAATTTGTTACAACAAGGCTACAAATTTTCACAAGGGATC
AACCCGAATGTGTTTGGTGCTGAGATGGCACAAATGCTTGAGGTTGGGGAGAAAAGTGGCAATGTGGCGAAAATGTGTGA
GCATATTAGTGAGATGTACCAACAAAAATTAGATTACCAAATTGATATTTTGTCTCAGCTATTAGAACCGATGCTAATGT
TGATAATGGGCGTGATTGTCGGCACTATTATTGTTGGGCTGTATTTACCGATTTTTGATATGGGGGCTTTGGTGGAGTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(268-390)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

53.865

100

0.541
  pilC Haemophilus influenzae Rd KW20

42.04

100

0.424
  pilC Haemophilus influenzae 86-028NP

41.045

100

0.414