Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HS054_RS12885 Genome accession   NZ_CP059244
Coordinates   2511863..2513059 (-) Length   398 a.a.
NCBI ID   WP_409042879.1    Uniprot ID   -
Organism   Mannheimia haemolytica strain 0001     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2506863..2518059
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HS054_RS12860 (HS054_12735) lptE 2508778..2509296 (+) 519 WP_409037689.1 LPS assembly lipoprotein LptE -
  HS054_RS12865 (HS054_12740) holA 2509339..2510364 (+) 1026 WP_409043435.1 DNA polymerase III subunit delta -
  HS054_RS12870 (HS054_12745) yacG 2510365..2510550 (-) 186 WP_006248406.1 DNA gyrase inhibitor YacG -
  HS054_RS12875 (HS054_12750) coaE 2510532..2511167 (-) 636 WP_409043437.1 dephospho-CoA kinase -
  HS054_RS12880 (HS054_12755) - 2511330..2511860 (-) 531 Protein_2488 prepilin peptidase -
  HS054_RS12885 (HS054_12760) pilC 2511863..2513059 (-) 1197 WP_409042879.1 type II secretion system F family protein Machinery gene
  HS054_RS12890 (HS054_12765) - 2513065..2513508 (-) 444 Protein_2490 pilus assembly protein PilB -
  HS054_RS12895 (HS054_12770) pilA 2513529..2514008 (-) 480 WP_006248401.1 prepilin peptidase-dependent pilin Machinery gene
  HS054_RS12900 (HS054_12775) radA 2514188..2515573 (+) 1386 WP_409042880.1 DNA repair protein RadA -
  HS054_RS12905 (HS054_12780) - 2515628..2515858 (-) 231 WP_006248398.1 YgjV family protein -
  HS054_RS12910 (HS054_12785) - 2515977..2516471 (-) 495 WP_240018338.1 dihydrofolate reductase -
  HS054_RS12915 (HS054_12790) proB 2516583..2517668 (+) 1086 WP_240025850.1 glutamate 5-kinase -

Sequence

Protein


Download         Length: 398 a.a.        Molecular weight: 45149.17 Da        Isoelectric Point: 9.3216

>NTDB_id=468133 HS054_RS12885 WP_409042879.1 2511863..2513059(-) (pilC) [Mannheimia haemolytica strain 0001]
MTKIYEFHWQAQSRFGQKQRGKRLATNRDMLENLLLAQGYQHIRISRNFVLSANPKKEEVNSLLSQLALLVNSAMPLKQA
LSMLLQNCRNIRLYLWLNELIQHIESGYAFSQSLEKLGEFVTNQEIQLIKMGEQSGKLGIMLTNLAESRAKLEKLAKKVK
KILFYPVIVLLISLALSIGLLVLIVPQFAQLYGSKDKTLPLITDILFTLSECLIEQGTVLLGTLLLAVIFYLFXAXKSRL
VAKWKMALWAKMPLFSRIIEQSRIIFFSQNIALMLNAHIPLDVALRSFLSEKNDDPILQQEIGTMLNLLQQGYKFSQGIN
PNVFGAEMAQMLEVGEKSGNVAKMCEHISEMYQQKLDYQIDILSQLLEPMLMLIMGVIVGTIIVGLYLPIFDMGALVE

Nucleotide


Download         Length: 1197 bp        

>NTDB_id=468133 HS054_RS12885 WP_409042879.1 2511863..2513059(-) (pilC) [Mannheimia haemolytica strain 0001]
ATGACGAAAATCTATGAATTTCATTGGCAAGCCCAGAGCCGATTTGGGCAAAAACAGCGGGGCAAGCGGTTGGCAACGAA
TCGAGACATGTTGGAAAACCTTTTGCTGGCACAAGGTTATCAGCATATTCGGATTAGCCGAAATTTTGTGCTTTCAGCAA
ACCCGAAAAAAGAAGAGGTGAATAGCTTGCTATCACAGCTTGCATTGTTGGTTAATTCTGCCATGCCGTTAAAACAGGCA
TTATCTATGTTGTTGCAAAACTGCCGAAATATCCGCCTTTATCTATGGCTTAATGAGCTGATTCAGCATATTGAAAGTGG
CTATGCTTTTTCACAATCGTTGGAGAAATTGGGTGAATTTGTGACCAATCAGGAAATTCAGCTAATCAAAATGGGCGAAC
AAAGCGGAAAACTGGGCATTATGCTGACTAATTTAGCTGAAAGCCGAGCGAAATTGGAAAAATTGGCGAAAAAAGTGAAG
AAAATCCTGTTTTACCCGGTGATTGTGTTGCTGATTTCGCTCGCTTTATCTATCGGGCTATTGGTTTTGATTGTACCGCA
GTTTGCCCAACTTTATGGCTCAAAAGACAAAACTTTACCCCTCATTACCGATATTTTATTTACCCTTTCCGAATGCTTGA
TTGAGCAAGGCACAGTATTACTTGGCACGTTACTACTAGCGGTCATTTTTTACCTGTTTNTTGCANAAAAGAGCAGGTTA
GTCGCAAAGTGGAAAATGGCTCTATGGGCTAAAATGCCACTGTTTAGCCGAATTATTGAGCAATCTCGCATTATCTTTTT
CAGCCAAAATATTGCCTTAATGCTGAATGCTCATATTCCGCTTGATGTTGCCTTGAGGTCGTTTTTATCCGAGAAAAATG
ATGACCCGATTTTACAGCAAGAAATTGGCACTATGCTTAATTTGTTACAACAAGGCTACAAATTTTCACAAGGGATCAAC
CCGAATGTGTTTGGTGCTGAGATGGCACAAATGCTTGAGGTTGGGGAGAAAAGTGGCAATGTGGCGAAAATGTGTGAGCA
TATTAGTGAGATGTACCAACAAAAATTAGATTACCAAATTGATATTTTGTCTCAGCTATTAGAACCGATGCTAATGTTGA
TAATGGGCGTGATTGTCGGCACTATTATTGTTGGGCTGTATTTACCGATTTTTGATATGGGGGCTTTGGTGGAGTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

53.75

100

0.54
  pilC Haemophilus influenzae Rd KW20

41.895

100

0.422
  pilC Haemophilus influenzae 86-028NP

40.898

100

0.412