Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HS055_RS10290 Genome accession   NZ_CP059243
Coordinates   2033273..2034469 (+) Length   398 a.a.
NCBI ID   WP_409037688.1    Uniprot ID   -
Organism   Mannheimia haemolytica strain 0002     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2028273..2039469
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HS055_RS10260 (HS055_10215) proB 2028664..2029752 (-) 1089 WP_409041906.1 glutamate 5-kinase -
  HS055_RS10265 (HS055_10220) folA 2029864..2030358 (+) 495 WP_006248397.1 type 3 dihydrofolate reductase -
  HS055_RS10270 (HS055_10225) - 2030477..2030707 (+) 231 WP_006248398.1 YgjV family protein -
  HS055_RS10275 (HS055_10230) radA 2030762..2032141 (-) 1380 WP_409041907.1 DNA repair protein RadA -
  HS055_RS10280 (HS055_10235) pilA 2032321..2032803 (+) 483 WP_275672167.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  HS055_RS10285 (HS055_10240) - 2032824..2033267 (+) 444 Protein_1980 pilus assembly protein PilB -
  HS055_RS10290 (HS055_10245) pilC 2033273..2034469 (+) 1197 WP_409037688.1 type II secretion system F family protein Machinery gene
  HS055_RS10295 - 2034472..2034675 (+) 204 WP_240018335.1 hypothetical protein -
  HS055_RS10300 - 2034746..2034952 (+) 207 Protein_1983 peptidase A24 -
  HS055_RS10305 (HS055_10255) coaE 2035166..2035801 (+) 636 WP_006248405.1 dephospho-CoA kinase -
  HS055_RS10310 (HS055_10260) yacG 2035783..2035968 (+) 186 WP_006248406.1 DNA gyrase inhibitor YacG -
  HS055_RS10315 (HS055_10265) holA 2035969..2036994 (-) 1026 WP_409038164.1 DNA polymerase III subunit delta -
  HS055_RS10320 (HS055_10270) lptE 2037037..2037555 (-) 519 WP_409037689.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 398 a.a.        Molecular weight: 45158.46 Da        Isoelectric Point: 9.4698

>NTDB_id=468106 HS055_RS10290 WP_409037688.1 2033273..2034469(+) (pilC) [Mannheimia haemolytica strain 0002]
MTKIYEFHWQAQSRFGQKQRGKRLATNRDMLENLLLAQGYQHIRISRNFVLSANPKKEEVNSLLSQLALLVNSAMPLKQA
LSMLLQNCRNIRLYLWLNELIQHIESGYAFSQSLEKLGEFVTNQEIQLIKMGEQSGKLGIMLTNLAESRAKLEKLAKKVK
KILFYPVIVLLISLALSIGLLVLIVPQFAQLYGSKDKTLPLITDILFTLSECLIEQGTVLLGTLLLAVIFYLXFAKKSRL
VAKWKMALWAKMPLFSRIIEQSRIIFFSQNIALMLNAHIPLDVALRSFLSEKNDDPILQQEIGTMLNLLQQGYKFSQGIN
PNVFGAEMAQMLEVGEKSGNVAKMCEHISEMYQQKLDYQIDILSQLLEPMLMLIMGVIVGTIIVGLYLPIFDMGALVE

Nucleotide


Download         Length: 1197 bp        

>NTDB_id=468106 HS055_RS10290 WP_409037688.1 2033273..2034469(+) (pilC) [Mannheimia haemolytica strain 0002]
ATGACGAAAATCTATGAATTTCATTGGCAAGCCCAGAGCCGATTTGGGCAAAAACAGCGGGGCAAGCGGTTGGCAACGAA
TCGAGACATGTTGGAAAACCTTTTGCTGGCACAAGGTTATCAGCATATTCGGATTAGCCGAAATTTTGTGCTTTCAGCAA
ACCCGAAAAAAGAAGAGGTGAATAGCTTGCTATCACAGCTTGCATTGTTGGTTAATTCTGCCATGCCGTTAAAACAGGCA
TTATCTATGTTGTTGCAAAACTGCCGAAATATCCGCCTTTATCTATGGCTTAATGAGCTGATTCAGCATATTGAAAGTGG
CTATGCTTTTTCACAATCGTTGGAGAAATTGGGTGAATTTGTGACCAATCAGGAAATTCAGCTAATCAAAATGGGCGAAC
AAAGCGGAAAACTGGGCATTATGCTGACTAATTTAGCTGAAAGCCGAGCGAAATTGGAAAAATTGGCGAAAAAAGTGAAG
AAAATCCTGTTTTACCCGGTGATTGTGTTGCTGATTTCGCTCGCTTTATCTATCGGGCTATTGGTTTTGATTGTACCGCA
GTTTGCCCAACTTTATGGCTCAAAAGACAAAACTTTACCCCTCATTACCGATATTTTATTTACCCTTTCCGAATGCTTGA
TTGAGCAAGGCACAGTATTACTTGGCACGTTACTACTAGCGGTCATTTTTTACCTGTTNTTTGCAAAAAAGAGCAGGTTA
GTCGCAAAGTGGAAAATGGCTCTATGGGCTAAAATGCCACTGTTTAGCCGAATTATTGAGCAATCTCGCATTATCTTTTT
CAGCCAAAATATTGCCTTAATGCTGAATGCTCATATTCCGCTTGATGTTGCCTTGAGGTCGTTTTTATCCGAGAAAAATG
ATGACCCGATTTTACAGCAAGAAATTGGCACTATGCTTAATTTGTTACAACAAGGCTACAAATTTTCACAAGGGATCAAC
CCGAATGTGTTTGGTGCTGAGATGGCACAAATGCTTGAGGTTGGGGAGAAAAGTGGCAATGTGGCGAAAATGTGTGAGCA
TATTAGTGAGATGTACCAACAAAAATTAGATTACCAAATTGATATTTTGTCTCAGCTATTAGAACCGATGCTAATGTTGA
TAATGGGCGTGATTGTCGGCACTATTATTGTTGGGCTGTATTTACCGATTTTTGATATGGGGGCTTTGGTGGAGTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

54

100

0.543
  pilC Haemophilus influenzae Rd KW20

41.895

100

0.422
  pilC Haemophilus influenzae 86-028NP

40.898

100

0.412