Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HS059_RS11765 Genome accession   NZ_CP059239
Coordinates   2312750..2313946 (+) Length   398 a.a.
NCBI ID   WP_409037688.1    Uniprot ID   -
Organism   Mannheimia haemolytica strain 0086     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2307750..2318946
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HS059_RS11735 (HS059_11680) proB 2308145..2309230 (-) 1086 WP_409037686.1 glutamate 5-kinase -
  HS059_RS11740 (HS059_11685) folA 2309342..2309836 (+) 495 WP_006248397.1 type 3 dihydrofolate reductase -
  HS059_RS11745 (HS059_11690) - 2309955..2310185 (+) 231 WP_006248398.1 YgjV family protein -
  HS059_RS11750 (HS059_11695) radA 2310240..2311619 (-) 1380 WP_409037687.1 DNA repair protein RadA -
  HS059_RS11755 (HS059_11700) pilA 2311870..2312280 (+) 411 WP_409038163.1 pilin Machinery gene
  HS059_RS11760 (HS059_11705) - 2312301..2312744 (+) 444 Protein_2270 pilus assembly protein PilB -
  HS059_RS11765 (HS059_11710) pilC 2312750..2313946 (+) 1197 WP_409037688.1 type II secretion system F family protein Machinery gene
  HS059_RS11770 - 2314225..2314431 (+) 207 Protein_2272 peptidase A24 -
  HS059_RS11775 (HS059_11720) coaE 2314645..2315280 (+) 636 WP_006248405.1 dephospho-CoA kinase -
  HS059_RS11780 (HS059_11725) yacG 2315262..2315447 (+) 186 WP_006248406.1 DNA gyrase inhibitor YacG -
  HS059_RS11785 (HS059_11730) holA 2315448..2316473 (-) 1026 WP_409038164.1 DNA polymerase III subunit delta -
  HS059_RS11790 (HS059_11735) lptE 2316516..2317034 (-) 519 WP_409037689.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 398 a.a.        Molecular weight: 45158.46 Da        Isoelectric Point: 9.4698

>NTDB_id=468019 HS059_RS11765 WP_409037688.1 2312750..2313946(+) (pilC) [Mannheimia haemolytica strain 0086]
MTKIYEFHWQAQSRFGQKQRGKRLATNRDMLENLLLAQGYQHIRISRNFVLSANPKKEEVNSLLSQLALLVNSAMPLKQA
LSMLLQNCRNIRLYLWLNELIQHIESGYAFSQSLEKLGEFVTNQEIQLIKMGEQSGKLGIMLTNLAESRAKLEKLAKKVK
KILFYPVIVLLISLALSIGLLVLIVPQFAQLYGSKDKTLPLITDILFTLSECLIEQGTVLLGTLLLAVIFYLXFAKKSRL
VAKWKMALWAKMPLFSRIIEQSRIIFFSQNIALMLNAHIPLDVALRSFLSEKNDDPILQQEIGTMLNLLQQGYKFSQGIN
PNVFGAEMAQMLEVGEKSGNVAKMCEHISEMYQQKLDYQIDILSQLLEPMLMLIMGVIVGTIIVGLYLPIFDMGALVE

Nucleotide


Download         Length: 1197 bp        

>NTDB_id=468019 HS059_RS11765 WP_409037688.1 2312750..2313946(+) (pilC) [Mannheimia haemolytica strain 0086]
ATGACGAAAATCTATGAATTTCATTGGCAAGCCCAGAGCCGATTTGGGCAAAAACAGCGGGGCAAGCGGTTGGCAACGAA
TCGAGACATGTTGGAAAACCTTTTGCTGGCACAAGGTTATCAGCATATTCGGATTAGCCGAAATTTTGTGCTTTCAGCAA
ACCCGAAAAAAGAAGAGGTGAATAGCTTGCTATCACAGCTTGCATTGTTGGTTAATTCTGCCATGCCGTTAAAACAGGCA
TTATCTATGTTGTTGCAAAACTGCCGAAATATCCGCCTTTATCTATGGCTTAATGAGCTGATTCAGCATATTGAAAGTGG
CTATGCTTTTTCACAATCGTTGGAGAAATTGGGTGAATTTGTGACCAATCAGGAAATTCAGCTAATCAAAATGGGCGAAC
AAAGCGGAAAACTGGGCATTATGCTGACTAATTTAGCTGAAAGCCGAGCGAAATTGGAAAAATTGGCGAAAAAAGTGAAG
AAAATCCTGTTTTACCCGGTGATTGTGTTGCTGATTTCGCTCGCTTTATCTATCGGGCTATTGGTTTTGATTGTACCGCA
GTTTGCCCAACTTTATGGCTCAAAAGACAAAACTTTACCCCTCATTACCGATATTTTATTTACCCTTTCCGAATGCTTGA
TTGAGCAAGGCACAGTATTACTTGGCACGTTACTACTAGCGGTCATTTTTTACCTGTTNTTTGCNAAAAAGAGCAGGTTA
GTCGCAAAGTGGAAAATGGCTCTATGGGCTAAAATGCCACTGTTTAGCCGAATTATTGAGCAATCTCGCATTATCTTTTT
CAGCCAAAATATTGCCTTAATGCTGAATGCTCATATTCCGCTTGATGTTGCCTTGAGGTCGTTTTTATCCGAGAAAAATG
ATGACCCGATTTTACAGCAAGAAATTGGCACTATGCTTAATTTGTTACAACAAGGCTACAAATTTTCACAAGGGATCAAC
CCGAATGTGTTTGGTGCTGAGATGGCACAAATGCTTGAGGTTGGGGAGAAAAGTGGCAATGTGGCGAAAATGTGTGAGCA
TATTAGTGAGATGTACCAACAAAAATTAGATTACCAAATTGATATTTTGTCTCAGCTATTAGAACCGATGCTAATGTTGA
TAATGGGCGTGATTGTCGGCACTATTATTGTTGGGCTGTATTTACCGATTTTTGATATGGGGGCTTTGGTGGAGTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

54

100

0.543
  pilC Haemophilus influenzae Rd KW20

41.895

100

0.422
  pilC Haemophilus influenzae 86-028NP

40.898

100

0.412