Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   HS060_RS12250 Genome accession   NZ_CP059238
Coordinates   2496100..2497245 (+) Length   381 a.a.
NCBI ID   WP_006251919.1    Uniprot ID   -
Organism   Mannheimia haemolytica strain 0152     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2491100..2502245
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HS060_RS12225 (HS060_12205) matP 2491585..2492031 (-) 447 WP_240021370.1 macrodomain Ter protein MatP -
  HS060_RS12230 (HS060_12210) - 2492124..2493761 (+) 1638 WP_409036029.1 AAA family ATPase -
  HS060_RS12235 (HS060_12215) fabA 2493874..2494404 (+) 531 WP_240017519.1 bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase -
  HS060_RS12240 (HS060_12220) rfaD 2494480..2495406 (-) 927 WP_006248766.1 ADP-glyceromanno-heptose 6-epimerase -
  HS060_RS12245 (HS060_12225) def 2495499..2496011 (-) 513 WP_006248765.1 peptide deformylase -
  HS060_RS12250 (HS060_12230) dprA 2496100..2497245 (+) 1146 WP_006251919.1 DNA-processing protein DprA Machinery gene
  HS060_RS12255 (HS060_12235) - 2497340..2498695 (-) 1356 WP_006251920.1 PTS ascorbate transporter subunit IIC -
  HS060_RS12260 (HS060_12240) - 2498708..2498977 (-) 270 WP_240026881.1 PTS sugar transporter subunit IIB -
  HS060_RS12265 (HS060_12245) - 2499208..2500230 (+) 1023 WP_240021372.1 LacI family DNA-binding transcriptional regulator -
  HS060_RS12270 (HS060_12250) secE 2500343..2500756 (+) 414 WP_409036030.1 preprotein translocase subunit SecE -
  HS060_RS12275 (HS060_12255) nusG 2500758..2501321 (+) 564 WP_006248760.1 transcription termination/antitermination protein NusG -
  HS060_RS12280 (HS060_12260) rplK 2501554..2501982 (+) 429 WP_006248758.1 50S ribosomal protein L11 -

Sequence

Protein


Download         Length: 381 a.a.        Molecular weight: 42217.37 Da        Isoelectric Point: 5.0956

>NTDB_id=467999 HS060_RS12250 WP_006251919.1 2496100..2497245(+) (dprA) [Mannheimia haemolytica strain 0152]
MAYQYDLLRLLQVQIGPQRIGRLLAELDFAEFCAYDKTQLRQIGWNEKQIQRWFNPDKNWIEQALTWAEQPNQQILSLFD
KAYPFLLRQISTAPPILFVKGNVESLSLPQIAIVGSRDYSPYGEYWAGQFAADLVKHNMAVTSGLAIGIDGFAHKKVVEY
QGITIAVLGSGLNRIYPARHQKLAEQIVESGGALVSEFSPNQPPIAENFPRRNRIISGLSLGTLVIEATINSGSLITARY
ALEQGREVFALPNAVQNPYAQGCHKLIKEGALLVEGVEDILEAVASQYQPQQIPLFDEPKPIVSTSLQAVKSSEKFAKNP
PNLTACQQQIYQHISLEPIAIDDLARATELTIETLLVELLGLELAGVIKQVSGGYVMDNGY

Nucleotide


Download         Length: 1146 bp        

>NTDB_id=467999 HS060_RS12250 WP_006251919.1 2496100..2497245(+) (dprA) [Mannheimia haemolytica strain 0152]
ATGGCATATCAGTATGATTTATTGCGTTTGTTGCAGGTGCAAATTGGTCCGCAGCGAATCGGACGGTTATTGGCAGAGTT
GGATTTTGCCGAATTTTGTGCCTACGATAAAACACAGTTAAGGCAGATCGGCTGGAATGAAAAGCAGATTCAGCGTTGGT
TTAATCCGGATAAAAATTGGATTGAGCAGGCACTAACTTGGGCGGAGCAGCCGAATCAGCAAATCCTGAGTTTATTTGAT
AAAGCTTATCCTTTCTTGCTGCGGCAAATTTCCACCGCTCCGCCGATTTTATTTGTAAAGGGTAATGTCGAAAGCCTTTC
CTTACCGCAAATTGCGATTGTTGGGAGTCGGGATTATTCGCCCTACGGTGAATATTGGGCGGGGCAATTTGCCGCTGACT
TGGTGAAGCACAATATGGCGGTGACTAGCGGTTTAGCGATTGGCATTGACGGTTTTGCACATAAAAAAGTAGTGGAATAT
CAAGGTATTACGATTGCTGTGTTGGGCAGTGGCTTAAACCGGATTTACCCCGCACGCCATCAAAAACTGGCTGAACAAAT
TGTCGAGTCAGGTGGTGCGTTGGTGTCTGAATTTTCACCTAATCAGCCTCCGATTGCTGAAAATTTCCCACGCCGAAACC
GCATAATCAGCGGTTTATCGCTCGGCACTTTGGTGATTGAAGCAACCATTAATAGTGGCTCTTTAATTACCGCTCGCTAT
GCCCTTGAACAAGGTCGGGAGGTGTTTGCGTTACCGAATGCGGTGCAAAACCCTTACGCACAAGGTTGCCACAAGCTAAT
TAAAGAAGGGGCGTTGCTTGTGGAGGGGGTGGAAGATATTTTAGAGGCGGTCGCCTCTCAATATCAACCTCAACAAATCC
CTTTGTTTGATGAGCCTAAGCCAATAGTAAGCACATCTTTACAAGCGGTCAAAAGTAGCGAAAAATTTGCAAAAAATCCG
CCAAATCTGACCGCTTGCCAGCAGCAAATTTATCAGCATATCAGCTTAGAGCCTATAGCGATTGACGATTTAGCCAGAGC
TACAGAGTTAACGATTGAGACATTGCTAGTTGAATTACTGGGGCTGGAATTAGCCGGCGTAATTAAACAAGTGAGTGGNG
GGTATGTGATGGATAATGGGTATTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(69-274)

DprA winged helix domain (DprA_WH)

(316-374)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Glaesserella parasuis strain SC1401

74.278

100

0.743
  dprA Haemophilus influenzae Rd KW20

51.02

90.026

0.459
  dprA Vibrio campbellii strain DS40M4

45.355

96.063

0.436
  dprA Vibrio cholerae strain A1552

42.033

95.538

0.402
  dprA Legionella pneumophila strain ERS1305867

41.279

90.289

0.373