Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   HS061_RS13645 Genome accession   NZ_CP059237
Coordinates   2621608..2622933 (-) Length   441 a.a.
NCBI ID   WP_240025195.1    Uniprot ID   -
Organism   Mannheimia haemolytica strain 0583     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2616608..2627933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HS061_RS13615 (HS061_13460) ruvB 2617117..2618121 (-) 1005 WP_006247944.1 Holliday junction branch migration DNA helicase RuvB -
  HS061_RS13620 (HS061_13465) ruvA 2618269..2618862 (-) 594 Protein_2641 Holliday junction branch migration protein RuvA -
  HS061_RS13625 (HS061_13470) - 2618974..2619597 (-) 624 WP_006247941.1 LysE family transporter -
  HS061_RS13630 (HS061_13475) - 2619604..2620077 (-) 474 WP_006247940.1 phosphatidylglycerophosphatase A -
  HS061_RS13635 (HS061_13480) thiL 2620082..2621062 (-) 981 WP_006247939.1 thiamine-phosphate kinase -
  HS061_RS13640 (HS061_13485) nusB 2621125..2621538 (-) 414 WP_006247938.1 transcription antitermination factor NusB -
  HS061_RS13645 (HS061_13490) comE 2621608..2622933 (-) 1326 WP_240025195.1 type IV pilus secretin PilQ Machinery gene
  HS061_RS13650 (HS061_13495) - 2622942..2623355 (-) 414 WP_006247936.1 hypothetical protein -
  HS061_RS13655 (HS061_13500) - 2623358..2623894 (-) 537 WP_006247935.1 hypothetical protein -
  HS061_RS13660 (HS061_13505) - 2623896..2624417 (-) 522 WP_006247934.1 hypothetical protein -
  HS061_RS13665 (HS061_13510) - 2624393..2625091 (-) 699 WP_240017830.1 competence protein ComA -
  HS061_RS13670 (HS061_13515) - 2625215..2627782 (+) 2568 WP_409041339.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 48891.02 Da        Isoelectric Point: 6.9251

>NTDB_id=467976 HS061_RS13645 WP_240025195.1 2621608..2622933(-) (comE) [Mannheimia haemolytica strain 0583]
MWRIFIYFLCGFSLAYANTISIVLXNAPTSLIFTYLAEETGKNMVLDDNIETKSTLRLENKSVDEIFKTLGKVNKLSLTQ
EDDIVYIHKXEEKAADLTPLPIMNLQNNGQNTPLVTAPKLITKTLKLHYAKASXEVIESLTKGSGTFLSENGYIHFDERS
NSLIVKDSAKSLKNIENLVKQLDQPTEQIAIEARIVTISSEHLQELGVRWGIFSRGAGHYKFGGRLEGNGLNNVTNNLNV
NFPITGGASAVLQVSSINSRVLDLELSALEQENSVEIIASPRLLTTNKKPASIKQGTEIPYVMYNTKSEATDVEFKEAVL
GLEVVPHLSTQNQILLDLIVTQNSPNSQSGSSGLITIDKQELNTQVFAKHGETIVLGGIFQHLTQKGEDKVPILGSIPFI
KRLFSQTRDKISKRELVIFVTPYILQSNEKSSNRKNQNSTS

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=467976 HS061_RS13645 WP_240025195.1 2621608..2622933(-) (comE) [Mannheimia haemolytica strain 0583]
ATGTGGCGAATTTTTATATATTTCTTATGCGGTTTTTCATTAGCCTATGCGAATACCATTTCCATAGTTTTANAAAATGC
TCCAACTTCGCTTATTTTTACTTATTTAGCGGAAGAAACCGGTAAAAATATGGTGCTTGATGATAATATTGAAACCAAAT
CAACACTACGATTAGAAAATAAATCGGTTGACGAGATTTTTAAAACGCTTGGCAAAGTCAATAAATTATCCTTAACGCAA
GAAGATGATATTGTTTATATTCACAAANAAGAGGAAAAAGCGGCTGACTTAACGCCTCTGCCAATAATGAATTTGCAAAA
TAATGGGCAAAATACACCGCTTGTCACCGCCCCTAAGTTAATCACAAAAACCTTGAAACTACATTATGCAAAGGCTTCCA
NNGAGGTGATTGAGTCGTTAACCAAAGGCAGCGGAACGTTTTTATCGGAAAACGGTTATATTCACTTTGATGAAAGAAGC
AATAGCCTGATTGTGAAAGACAGTGCAAAATCGCTTAAAAATATCGAGAATTTAGTAAAACAGCTCGACCAACCCACCGA
GCAAATTGCGATTGAGGCTAGAATTGTCACTATCAGTAGCGAGCATTTGCAAGAGCTTGGCGTTCGCTGGGGAATTTTTT
CTCGTGGGGCTGGGCACTATAAATTTGGCGGACGGCTGGAAGGCAATGGACTCAACAATGTCACCAATAACTTAAATGTA
AATTTTCCGATTACTGGTGGAGCATCTGCCGTATTACAGGTTTCGTCCATTAATAGCAGAGTGCTTGATTTAGAATTAAG
TGCATTAGAACAAGAAAATAGTGTGGAAATTATTGCCAGCCCACGCCTGTTAACCACCAATAAAAAGCCGGCAAGTATCA
AGCAAGGCACGGAAATTCCTTATGTGATGTACAACACCAAATCGGAAGCCACCGATGTCGAATTTAAAGAAGCGGTATTA
GGGCTTGAAGTCGTTCCACACCTTTCAACCCAAAATCAAATTCTACTCGATCTGATCGTTACCCAAAATTCGCCAAATTC
CCAATCCGGCAGTAGTGGCTTAATTACGATTGATAAACAAGAGCTAAATACGCAAGTATTTGCCAAACACGGCGAAACCA
TTGTACTTGGTGGTATTTTTCAACATTTAACCCAAAAAGGCGAAGATAAAGTGCCGATTTTAGGCTCAATTCCCTTCATC
AAGCGGTTATTTAGTCAAACTCGAGATAAAATCAGCAAAAGAGAGCTAGTCATTTTTGTGACGCCTTATATCCTTCAATC
TAATGAAAAGAGCAGCAACCGCAAAAATCAAAATAGCACATCATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(268-425)

Bacterial type II/III secretion system short domain (Secretin_N)

(58-188)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Glaesserella parasuis strain SC1401

63.785

97.052

0.619
  comE Haemophilus influenzae Rd KW20

50.337

100

0.508
  comE Haemophilus influenzae 86-028NP

50.229

98.866

0.497
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

37.915

95.692

0.363
  pilQ Vibrio cholerae strain A1552

37.915

95.692

0.363
  pilQ Vibrio campbellii strain DS40M4

37.209

97.506

0.363