Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/comE1   Type   Machinery gene
Locus tag   HS061_RS12020 Genome accession   NZ_CP059237
Coordinates   2307919..2308257 (-) Length   112 a.a.
NCBI ID   WP_006251644.1    Uniprot ID   A0A248ZWT2
Organism   Mannheimia haemolytica strain 0583     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2302919..2313257
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HS061_RS12005 (HS061_11860) - 2302921..2304390 (-) 1470 WP_240024991.1 class I SAM-dependent DNA methyltransferase -
  HS061_RS12010 (HS061_11865) hsdR 2304438..2306789 (-) 2352 WP_409041257.1 EcoAI/FtnUII family type I restriction enzme subunit R -
  HS061_RS12015 (HS061_11870) asd 2306861..2307754 (-) 894 WP_409041258.1 archaetidylserine decarboxylase -
  HS061_RS12020 (HS061_11875) comEA/comE1 2307919..2308257 (-) 339 WP_006251644.1 ComEA family DNA-binding protein Machinery gene
  HS061_RS12025 (HS061_11880) - 2308550..2309875 (+) 1326 WP_409041259.1 LysM-like peptidoglycan-binding domain-containing protein -
  HS061_RS12030 (HS061_11885) - 2309939..2310355 (+) 417 WP_240024996.1 MliC family protein -
  HS061_RS12035 (HS061_11890) waaF 2310466..2311503 (+) 1038 WP_409041260.1 lipopolysaccharide heptosyltransferase II -
  HS061_RS12040 (HS061_11895) rfaC 2311569..2312528 (+) 960 WP_240028220.1 lipopolysaccharide heptosyltransferase RfaC -
  HS061_RS12045 (HS061_11900) rpsL 2312649..2313023 (+) 375 WP_240024998.1 30S ribosomal protein S12 -

Sequence

Protein


Download         Length: 112 a.a.        Molecular weight: 12111.91 Da        Isoelectric Point: 10.0993

>NTDB_id=467972 HS061_RS12020 WP_006251644.1 2307919..2308257(-) (comEA/comE1) [Mannheimia haemolytica strain 0583]
MKKIKQLGLTFLFGLNAMAFAQTPPTTMPVEQNAVTQPVQQTQITNANAVNINTASAAELQDKLVGIGQKKAQAIVDYRT
KNGNFKNIEQLAEVSGIGQATVEKNRANIILE

Nucleotide


Download         Length: 339 bp        

>NTDB_id=467972 HS061_RS12020 WP_006251644.1 2307919..2308257(-) (comEA/comE1) [Mannheimia haemolytica strain 0583]
ATGAAGAAAATCAAACAACTTGGTCTAACATTCTTGTTTGGCTTAAATGCAATGGCTTTTGCCCAAACACCGCCAACTAC
AATGCCTGTTGAACAAAATGCAGTCACTCAACCCGTACAGCAAACACAAATCACCAACGCTAATGCGGTAAATATCAATA
CTGCTAGTGCTGCTGAATTGCAAGACAAGCTAGTGGGAATTGGGCAGAAAAAAGCTCAAGCGATTGTCGATTACCGTACT
AAAAACGGCAATTTTAAAAACATTGAGCAACTTGCTGAAGTCTCCGGAATTGGGCAAGCAACGGTAGAAAAAAATCGAGC
CAATATTATTTTAGAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(46-109)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A248ZWT2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/comE1 Glaesserella parasuis strain SC1401

59.292

100

0.598
  comE1/comEA Haemophilus influenzae Rd KW20

52.747

81.25

0.429
  comEA Vibrio cholerae C6706

54.651

76.786

0.42
  comEA Vibrio cholerae strain A1552

54.651

76.786

0.42