Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   HS061_RS10955 Genome accession   NZ_CP059237
Coordinates   2093808..2094956 (+) Length   382 a.a.
NCBI ID   WP_006248764.1    Uniprot ID   A0A547ELA4
Organism   Mannheimia haemolytica strain 0583     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2088808..2099956
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HS061_RS10930 (HS061_10795) matP 2089294..2089743 (-) 450 WP_240024877.1 macrodomain Ter protein MatP -
  HS061_RS10935 (HS061_10800) - 2089836..2091473 (+) 1638 WP_409041203.1 AAA family ATPase -
  HS061_RS10940 (HS061_10805) fabA 2091586..2092116 (+) 531 WP_240017519.1 bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase -
  HS061_RS10945 (HS061_10810) rfaD 2092184..2093113 (-) 930 WP_240020345.1 ADP-glyceromanno-heptose 6-epimerase -
  HS061_RS10950 (HS061_10815) def 2093207..2093719 (-) 513 WP_006248765.1 peptide deformylase -
  HS061_RS10955 (HS061_10820) dprA 2093808..2094956 (+) 1149 WP_006248764.1 DNA-processing protein DprA Machinery gene
  HS061_RS10960 (HS061_10825) - 2095051..2096403 (-) 1353 WP_409038108.1 PTS ascorbate transporter subunit IIC -
  HS061_RS10965 (HS061_10830) - 2096416..2096685 (-) 270 WP_006248763.1 PTS sugar transporter subunit IIB -
  HS061_RS10970 (HS061_10835) - 2096917..2097939 (+) 1023 WP_006248762.1 LacI family DNA-binding transcriptional regulator -
  HS061_RS10975 (HS061_10840) secE 2098052..2098468 (+) 417 WP_240024882.1 preprotein translocase subunit SecE -
  HS061_RS10980 (HS061_10845) nusG 2098470..2099033 (+) 564 WP_006248760.1 transcription termination/antitermination protein NusG -
  HS061_RS10985 (HS061_10850) rplK 2099313..2099693 (+) 381 WP_240026882.1 50S ribosomal protein L11 -

Sequence

Protein


Download         Length: 382 a.a.        Molecular weight: 42497.83 Da        Isoelectric Point: 5.2272

>NTDB_id=467970 HS061_RS10955 WP_006248764.1 2093808..2094956(+) (dprA) [Mannheimia haemolytica strain 0583]
MAYHYDLLRLLQVPQMGAQRIGRLLAELNFAEFCHYDKLQLKQIGWNEKQIQRWFNPDQKWIDQAMTWSELPNQQIVTLF
DENYPFLLKQISTAPPLIYVKGNVESLSLPQIAIVGSRDYSHYGEYWAGQFAAELARHNIIITSGLAIGIDGFAHQKIVM
EQGITIAVLGSGLNQVYPARHKKLAEQIVDLGGALVSEFSPNQPPVAENFPRRNRIISGLSLGTLVIEATLNSGSLITAR
YALEQGREVFALPNAVQNPYAQGCHKLIKEGALLVEGVEDILEVVASQYQPQQIPLFDESKPTVSTSLQAVKNSEKFAKN
LPSLTACQQQIYQHISLEPMAIDDLAKVTELTIEILLVELLGLELAGVIKQVSGGYVMDNGY

Nucleotide


Download         Length: 1149 bp        

>NTDB_id=467970 HS061_RS10955 WP_006248764.1 2093808..2094956(+) (dprA) [Mannheimia haemolytica strain 0583]
ATGGCATATCACTACGATTTATTACGATTATTACAAGTGCCGCAAATGGGGGCTCAACGTATAGGGCGATTATTGGCGGA
ACTCAATTTTGCTGAATTTTGCCACTATGACAAACTTCAACTCAAACAAATAGGTTGGAATGAAAAGCAAATTCAACGTT
GGTTTAATCCTGATCAAAAGTGGATTGATCAGGCGATGACTTGGTCAGAATTGCCAAATCAGCAAATTGTGACACTCTTT
GATGAAAATTATCCGTTTCTCTTAAAACAAATTTCGACTGCGCCACCGTTAATTTATGTAAAGGGAAATGTGGAAAGCCT
TTCTCTGCCACAAATTGCGATTGTTGGCAGCCGAGACTATTCTCATTATGGTGAATATTGGGCTGGGCAATTTGCTGCCG
AGTTAGCTCGCCATAATATTATCATTACCAGCGGTTTAGCCATTGGTATTGACGGTTTTGCCCATCAAAAAATCGTTATG
GAACAAGGCATAACGATTGCCGTGTTAGGGAGTGGATTAAATCAAGTCTATCCTGCTCGCCATAAAAAATTAGCCGAACA
AATTGTTGATTTAGGTGGTGCATTGGTGTCGGAGTTCTCGCCTAATCAGCCGCCGGTGGCAGAAAATTTTCCTCGTCGTA
ATCGAATTATTAGTGGCTTATCGCTCGGCACTTTAGTTATTGAAGCAACGCTTAATAGTGGTTCACTGATTACCGCTCGT
TATGCCCTTGAACAAGGTAGGGAAGTGTTTGCGTTACCGAATGCGGTACAAAACCCTTACGCACAAGGTTGCCACAAGCT
AATTAAAGAAGGGGCATTGCTCGTGGAAGGTGTGGAAGATATTTTAGAGGTGGTCGCCTCGCAATATCAACCTCAGCAAA
TCCCTTTGTTTGATGAGTCTAAGCCAACAGTAAGCACATCTTTACAAGCGGTCAAAAACAGCGAAAAATTCGCNAAAAAT
CTGCCAAGTCTGACCGCTTGCCAGCAGCAAATTTATCAGCATATCAGCTTAGAGCCGATGGCAATTGATGATTTAGCCAA
AGTTACGGAGTTGACGATTGAAATATTGCTGGTTGAATTACTGGGTCTGGAATTAGCCGGTGTGATTAAACAAGTGAGTG
GGGGGTATGTGATGGATAATGGGTATTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(73-275)

DprA winged helix domain (DprA_WH)

(317-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A547ELA4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Glaesserella parasuis strain SC1401

73.615

99.215

0.73
  dprA Haemophilus influenzae Rd KW20

51.304

90.314

0.463
  dprA Vibrio campbellii strain DS40M4

44.744

97.12

0.435
  dprA Vibrio cholerae strain A1552

42.588

97.12

0.414
  dprA Legionella pneumophila strain ERS1305867

40.29

90.314

0.364