Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   HS073_RS13895 Genome accession   NZ_CP059226
Coordinates   2699871..2701196 (+) Length   441 a.a.
NCBI ID   WP_409036891.1    Uniprot ID   -
Organism   Mannheimia haemolytica strain 0739     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2694871..2706196
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HS073_RS13870 (HS073_13765) - 2695019..2697586 (-) 2568 Protein_2686 penicillin-binding protein 1A -
  HS073_RS13875 (HS073_13770) - 2697710..2698408 (+) 699 WP_240020005.1 competence protein ComA -
  HS073_RS13880 (HS073_13775) - 2698384..2698905 (+) 522 WP_006247934.1 hypothetical protein -
  HS073_RS13885 (HS073_13780) - 2698907..2699443 (+) 537 WP_006247935.1 hypothetical protein -
  HS073_RS13890 (HS073_13785) - 2699446..2699862 (+) 417 WP_409036890.1 hypothetical protein -
  HS073_RS13895 (HS073_13790) comE 2699871..2701196 (+) 1326 WP_409036891.1 type IV pilus secretin PilQ Machinery gene
  HS073_RS13900 (HS073_13795) nusB 2701267..2701680 (+) 414 WP_006247938.1 transcription antitermination factor NusB -
  HS073_RS13905 (HS073_13800) thiL 2701743..2702723 (+) 981 WP_006247939.1 thiamine-phosphate kinase -
  HS073_RS13910 (HS073_13805) - 2702728..2703201 (+) 474 WP_240028074.1 phosphatidylglycerophosphatase A -
  HS073_RS13915 (HS073_13810) - 2703208..2703831 (+) 624 WP_006247941.1 LysE family transporter -
  HS073_RS13920 (HS073_13815) ruvA 2703943..2704536 (+) 594 Protein_2696 Holliday junction branch migration protein RuvA -
  HS073_RS13925 (HS073_13820) ruvB 2704684..2705691 (+) 1008 WP_409036892.1 Holliday junction branch migration DNA helicase RuvB -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 48896.79 Da        Isoelectric Point: 7.1883

>NTDB_id=467793 HS073_RS13895 WP_409036891.1 2699871..2701196(+) (comE) [Mannheimia haemolytica strain 0739]
MWRIFIYFLCGFSLAYANTISIVXKNAPTSLIFTYLAEETGKNMVLDDNIETKSTLRLENKSVDEIFKTLGKVNKLSLTQ
EDDIVYIHXKEEKAADLTPLPIMNLQNNGQNTPLVTAPKLITKTLKLHYAKASXEVIESLTKGSGTFLSENGYIHFDERS
NSLIVKDSAKSLKNIENLVKQLDQPTEQIAIEARIVTISSEHLQELGVRWGIFSRGAGHYKFGGRLEGNGLNNVTNNLNV
NFPITGGASAVLQVSSINSRVLDLELSALEQENSVEIIASPRLLTTNKKPASIKQGTEIPYVMYNTKSEATDVEFKEAVL
GLEVVPHLSTQNQILLDLIVTQNSPNSQSGSSGLITIDKQELNTQVFAKHGETIVLGGIFQHLTXKGEDKVPILGSIPFI
KRLFSQTRDKISKRELVIFVTPYILQSNEKSSNRKNQNSTS

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=467793 HS073_RS13895 WP_409036891.1 2699871..2701196(+) (comE) [Mannheimia haemolytica strain 0739]
ATGTGGCGAATTTTTATATATTTCTTATGCGGTTTTTCATTAGCCTATGCGAATACCATTTCCATAGTTTTNAAAAATGC
TCCAACTTCGCTTATTTTTACTTATTTAGCGGAAGAAACCGGTAAAAATATGGTGCTTGATGATAATATTGAAACCAAAT
CAACACTACGATTAGAAAATAAATCGGTTGACGAGATTTTTAAAACGCTTGGCAAAGTCAATAAATTATCCTTAACGCAA
GAAGATGATATTGTTTATATTCACAANAAAGAGGAAAAAGCGGCTGACTTAACGCCTCTGCCAATAATGAATTTGCAAAA
TAATGGGCAAAATACACCGCTTGTCACCGCCCCTAAGTTAATCACAAAAACCTTGAAACTACATTATGCAAAGGCTTCCN
NAGAGGTGATTGAGTCGTTAACCAAAGGCAGCGGAACGTTTTTATCGGAAAACGGTTATATTCACTTTGATGAAAGAAGC
AATAGCCTGATTGTGAAAGACAGTGCAAAATCGCTTAAAAATATCGAGAATTTAGTAAAACAGCTCGACCAACCCACCGA
GCAAATTGCGATTGAGGCTAGAATTGTCACTATCAGTAGCGAGCATTTGCAAGAGCTTGGCGTTCGCTGGGGAATTTTTT
CTCGTGGGGCTGGGCACTATAAATTTGGCGGACGGCTGGAAGGCAATGGACTCAACAATGTCACCAATAACTTAAATGTA
AATTTTCCGATTACTGGTGGAGCATCTGCCGTATTACAGGTTTCGTCCATTAATAGCAGAGTGCTTGATTTAGAATTAAG
TGCATTAGAACAAGAAAATAGTGTGGAAATTATTGCCAGCCCACGCCTGTTAACCACCAATAAAAAGCCGGCAAGTATCA
AGCAAGGCACGGAAATTCCTTATGTGATGTACAACACCAAATCGGAAGCCACCGATGTCGAATTTAAAGAAGCGGTATTA
GGGCTTGAAGTCGTTCCACACCTTTCAACCCAAAATCAAATTCTACTCGATCTGATCGTTACCCAAAATTCGCCAAATTC
CCAATCCGGCAGTAGTGGCTTAATTACGATTGATAAACAAGAGCTAAATACGCAAGTATTTGCCAAACACGGCGAAACCA
TTGTACTTGGTGGTATTTTTCAACATTTAACCCANAAAGGCGAAGATAAAGTGCCGATTTTAGGCTCAATTCCCTTCATC
AAGCGGTTATTTAGTCAAACTCGAGATAAAATCAGCAAAAGAGAGCTAGTCATTTTTGTGACGCCTTATATCCTTCAATC
TAATGAAAAGAGCAGCAACCGCAAAAATCAAAATAGCACATCATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(268-425)

Bacterial type II/III secretion system short domain (Secretin_N)

(58-188)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Glaesserella parasuis strain SC1401

63.785

97.052

0.619
  comE Haemophilus influenzae Rd KW20

50.112

100

0.506
  comE Haemophilus influenzae 86-028NP

50

98.866

0.494
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

38.152

95.692

0.365
  pilQ Vibrio cholerae strain A1552

38.152

95.692

0.365
  pilQ Vibrio campbellii strain DS40M4

37.442

97.506

0.365