Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB10   Type   Machinery gene
Locus tag   HPKB_RS06490 Genome accession   NC_017354
Coordinates   1332945..1334081 (-) Length   378 a.a.
NCBI ID   WP_001045779.1    Uniprot ID   -
Organism   Helicobacter pylori 52     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1327945..1339081
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPKB_RS08170 - 1328837..1329130 (+) 294 WP_042350090.1 hypothetical protein -
  HPKB_RS06475 (HPKB_1278) - 1329379..1330311 (-) 933 WP_001002433.1 GDP-L-fucose synthase family protein -
  HPKB_RS06480 (HPKB_1279) gmd 1330304..1331449 (-) 1146 WP_014533533.1 GDP-mannose 4,6-dehydratase -
  HPKB_RS06485 (HPKB_1280) - 1331463..1332875 (-) 1413 WP_000694850.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HPKB_RS06490 (HPKB_1281) comB10 1332945..1334081 (-) 1137 WP_001045779.1 DNA type IV secretion system protein ComB10 Machinery gene
  HPKB_RS06495 (HPKB_1282) comB9 1334074..1335036 (-) 963 WP_014533534.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HPKB_RS06500 (HPKB_1283) comB8 1335036..1335773 (-) 738 WP_000660526.1 type IV secretion system protein Machinery gene
  HPKB_RS06505 (HPKB_1284) comB7 1335770..1335895 (-) 126 WP_001217874.1 hypothetical protein Machinery gene
  HPKB_RS06510 (HPKB_1285) comB6 1335911..1336966 (-) 1056 WP_000786672.1 P-type conjugative transfer protein TrbL Machinery gene
  HPKB_RS06515 (HPKB_1286) - 1336974..1337969 (-) 996 WP_000468447.1 PDZ domain-containing protein -
  HPKB_RS06520 (HPKB_1287) - 1337969..1338262 (-) 294 WP_000347922.1 YbaB/EbfC family nucleoid-associated protein -
  HPKB_RS06525 (HPKB_1288) panD 1338273..1338623 (-) 351 WP_000142205.1 aspartate 1-decarboxylase -

Sequence

Protein


Download         Length: 378 a.a.        Molecular weight: 42159.80 Da        Isoelectric Point: 9.8942

>NTDB_id=46714 HPKB_RS06490 WP_001045779.1 1332945..1334081(-) (comB10) [Helicobacter pylori 52]
MNKWIKGVLVFVGGFATIVTISLIYHQKPKAPLNNQPNLLNDDEVKYPLQDYTFTQNPQPTNTESSKDATIKALQEQLKA
ALKALNSKEMNYSKEETFTSPPIDLKANTTPPKKDFSLKQLDLLASRITPFKQSPKNYEENLIFPMDNPKGIDGFTNLKE
KDIATNENKLLRTITADKMIPAFLITPISSQIAGKVIAQVESDIFAHMGKAVLIPKGSKVIGYYSNNNKMGEYRLDIVWS
RIITPHGINIMLTNAKGADIKGYNGLVGELIERNFQRYGVPLLLSTLTNGLLIGITSALNNRGNKEGATNFFGDYLLLQL
MRQSGMGINQVVNQILRDKSKIAPIVVIREGSRVFISPNTDIFFPIPKENEVIAEFLK

Nucleotide


Download         Length: 1137 bp        

>NTDB_id=46714 HPKB_RS06490 WP_001045779.1 1332945..1334081(-) (comB10) [Helicobacter pylori 52]
ATGAATAAGTGGATTAAGGGGGTGCTTGTTTTTGTAGGGGGTTTTGCAACGATTGTAACAATTTCTTTAATCTATCATCA
AAAGCCAAAAGCCCCCCTAAATAACCAACCCAACCTTTTGAATGACGATGAGGTGAAATACCCCTTACAAGACTACACCT
TCACCCAAAACCCACAGCCAACTAACACAGAAAGCTCCAAAGACGCTACCATCAAAGCTTTACAAGAACAGCTAAAAGCC
GCTTTAAAAGCCCTAAACTCCAAAGAAATGAACTATTCTAAAGAAGAAACTTTTACTAGCCCTCCCATAGATTTAAAAGC
AAACACAACCCCCCCTAAAAAAGACTTTTCTCTAAAGCAATTAGATTTACTAGCCTCTCGCATCACCCCTTTCAAACAAA
GCCCTAAAAATTACGAAGAAAACCTGATTTTTCCCATGGATAACCCTAAGGGCATTGATGGTTTTACCAACCTTAAAGAA
AAAGACATCGCCACCAATGAAAACAAGCTTTTACGCACCATTACAGCCGATAAAATGATACCCGCCTTTCTCATCACGCC
CATTTCTAGCCAGATCGCTGGTAAAGTCATCGCGCAAGTGGAAAGCGATATTTTTGCTCACATGGGCAAGGCCGTCTTAA
TCCCCAAAGGCTCTAAAGTCATAGGCTATTACAGCAACAACAACAAAATGGGCGAATACCGCTTGGATATTGTATGGAGC
CGCATCATCACCCCCCATGGCATCAATATCATGCTCACTAACGCTAAAGGGGCGGACATTAAAGGCTATAACGGCTTAGT
GGGGGAATTGATTGAAAGGAATTTCCAGCGCTATGGCGTGCCGTTACTGCTTTCTACTCTCACTAACGGCTTATTGATTG
GGATCACTTCGGCCTTAAACAACAGGGGCAATAAAGAAGGAGCTACCAATTTCTTTGGGGATTATCTTTTATTGCAATTG
ATGAGACAAAGCGGCATGGGGATCAATCAAGTGGTCAATCAAATTTTAAGAGACAAGAGCAAAATCGCTCCTATTGTGGT
GATTAGAGAGGGAAGCAGGGTCTTCATTTCGCCCAATACTGACATCTTCTTTCCTATACCCAAAGAGAATGAAGTCATCG
CTGAGTTTTTGAAGTGA

Domains

Predicted by InterproScan.

Bacterial conjugation TrbI-like protein (TrbI)

(173-364)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB10 Helicobacter pylori P1

96.296

100

0.963

Multiple sequence alignment