Detailed information NTG0466542

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: A0R66_RS10575
• Genome accession: NZ_CP059035
• Coordinates: 2248260..2249594 (+)
• Length: 444 a.a.
• NCBI ID: WP_061406404.1
• Uniprot ID: -
• Organism: Pasteurella multocida subsp. multocida strain HN141014
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2243260..2254594

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A0R66_RS10550 (A0R66_010520)	-	2243336..2245897 (-)	2562	WP_061406401.1	penicillin-binding protein 1A	-
A0R66_RS10555 (A0R66_010525)	-	2246033..2246806 (+)	774	WP_061406402.1	pilus assembly protein PilM	-
A0R66_RS10560 (A0R66_010530)	-	2246846..2247361 (+)	516	WP_064972571.1	competence protein ComB	-
A0R66_RS10565 (A0R66_010535)	-	2247361..2247885 (+)	525	WP_061406403.1	hypothetical protein	-
A0R66_RS10570 (A0R66_010540)	-	2247888..2248250 (+)	363	WP_014668625.1	pilus assembly protein PilP	-
A0R66_RS10575 (A0R66_010545)	comE	2248260..2249594 (+)	1335	WP_061406404.1	type IV pilus secretin PilQ	Machinery gene
A0R66_RS10580 (A0R66_010550)	aroK	2249777..2250304 (+)	528	WP_005717623.1	shikimate kinase AroK	-
A0R66_RS10585 (A0R66_010555)	aroB	2250321..2251409 (+)	1089	WP_061406405.1	3-dehydroquinate synthase	-
A0R66_RS10590 (A0R66_010560)	-	2251413..2252318 (+)	906	WP_005723696.1	Dam family site-specific DNA-(adenine-N6)-methyltransferase	-
A0R66_RS10595 (A0R66_010565)	-	2252366..2252671 (-)	306	WP_005723691.1	DUF721 domain-containing protein	-
A0R66_RS10600 (A0R66_010570)	secM	2252764..2253075 (+)	312	WP_005723689.1	secA translation cis-regulator SecM	-

Sequence

Protein

• Length: 444 a.a.
• Molecular weight: 49240.64 Da
• Isoelectric Point: 8.0315

>NTDB_id=466542 A0R66_RS10575 WP_061406404.1 2248260..2249594(+) (comE) [Pasteurella multocida subsp. multocida strain HN141014]
MWRAFRKISFVYFLCGVAYVGSSQAQDAEHFYLRLKQAPLVEMLQYLALQQHQDLLIDDHLEGTLSLQMKKTTFEKCLQS
IARMKQLELHQEGKSYYLTSPSGVAANDTHHPTSLMTSSIKLHFAKAAEVVKSLTSGQGSLLSVGGSLSFDERTNLLLIQ
DEPQSIQRIKALVAEMDKPIEQIAIEARIVTMTDESLQELGVRWGLFQATEQAHTIAGSLAANGFSNIENQLNVNFSTNS
APVGSIALQLAKINGRLLDLELTALEREKHIEIIASPRLLTTNKKSASIKQGTEIPYVMKRGKDKSESVEFREAVLGLDV
TPHISKDNTILLDLLITQNTLGAPVVYDKGEIVSIDKQEINTQVVAQDGETIVLGGVFHDTMTKGVNKVPLLGDLPLLKH
VFSQKTERHQKRELVIFVTPHIIKPSQGSPEQKTTRVKKSAKSR

Nucleotide

• Length: 1335 bp

>NTDB_id=466542 A0R66_RS10575 WP_061406404.1 2248260..2249594(+) (comE) [Pasteurella multocida subsp. multocida strain HN141014]
ATGTGGCGAGCATTCAGAAAAATATCTTTTGTGTACTTTTTATGTGGGGTTGCTTATGTTGGAAGTAGTCAAGCACAAGA
CGCAGAACATTTTTATTTACGTTTAAAACAAGCGCCTTTAGTTGAAATGTTACAGTATTTAGCATTGCAACAACATCAGG
ATTTGTTAATCGATGATCATTTAGAGGGCACATTATCATTACAGATGAAAAAGACAACCTTTGAGAAATGTTTACAGTCG
ATTGCAAGAATGAAACAACTTGAGTTACATCAAGAAGGAAAATCCTATTATTTAACTTCCCCTTCAGGTGTTGCAGCAAA
CGATACTCATCATCCTACGTCATTGATGACATCTTCAATAAAATTGCATTTTGCCAAAGCTGCAGAGGTGGTGAAATCTT
TAACTTCAGGGCAGGGAAGTTTACTTTCTGTCGGGGGGAGTTTGAGTTTTGATGAGCGGACTAATTTACTGCTGATTCAG
GATGAACCGCAATCAATACAGCGTATTAAAGCATTAGTAGCAGAAATGGATAAACCCATTGAACAAATTGCGATCGAAGC
TAGGATTGTGACGATGACAGACGAAAGTTTGCAGGAACTTGGTGTAAGATGGGGGCTATTTCAAGCAACAGAACAGGCAC
ATACTATTGCGGGGAGTTTAGCCGCGAACGGCTTTTCGAATATAGAAAACCAATTAAATGTGAATTTCTCGACCAATAGT
GCACCTGTTGGTTCCATCGCCTTACAGTTGGCGAAAATAAATGGTCGATTATTAGACTTGGAATTAACTGCCTTGGAGCG
AGAAAAGCATATTGAGATTATTGCGAGTCCTCGTTTATTAACAACGAATAAAAAAAGTGCCAGTATCAAACAAGGGACAG
AAATTCCTTATGTGATGAAACGGGGAAAAGATAAAAGCGAATCGGTGGAATTTCGAGAAGCTGTATTAGGTTTAGATGTG
ACACCGCATATCTCAAAAGACAACACGATTTTATTAGATTTATTGATTACACAAAATACATTAGGTGCACCGGTAGTGTA
TGATAAAGGCGAAATTGTTTCGATCGATAAACAGGAAATCAATACTCAAGTCGTCGCTCAAGATGGTGAAACCATCGTTT
TAGGTGGGGTGTTTCATGATACGATGACAAAGGGAGTCAATAAAGTACCATTACTAGGGGATTTGCCTTTGCTTAAACAT
GTGTTTAGCCAAAAAACTGAACGTCATCAAAAGCGGGAATTAGTGATTTTTGTCACTCCTCATATTATCAAACCTAGCCA
AGGTTCGCCTGAACAAAAAACAACAAGAGTTAAAAAATCTGCAAAATCGAGGTGA

Domains

Predicted by InterproScan.

• Bacterial type II and III secretion system protein (Secretin) (264-424)

• Bacterial type II/III secretion system short domain (Secretin_N) (119-182)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Haemophilus influenzae Rd KW20	62.037	97.297	0.604
comE	Haemophilus influenzae 86-028NP	61.343	97.297	0.597
comE	Glaesserella parasuis strain SC1401	48.961	97.523	0.477
pilQ	Vibrio campbellii strain DS40M4	39.524	94.595	0.374
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	39.806	92.793	0.369
pilQ	Vibrio cholerae strain A1552	39.806	92.793	0.369