Detailed information NTG0466067

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: HZ310_RS02290
• Genome accession: NZ_CP058951
• Coordinates: 464634..465809 (+)
• Length: 391 a.a.
• NCBI ID: WP_024719243.1
• Uniprot ID: A0A081LEM4
• Organism: Bacillus pumilus strain UAMX
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 459634..470809

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HZ310_RS02270 (HZ310_02270)	-	460279..461469 (+)	1191	WP_257474644.1	glycosyltransferase	-
HZ310_RS02275 (HZ310_02275)	-	461601..462668 (+)	1068	WP_058013554.1	glycosyltransferase family 4 protein	-
HZ310_RS02280 (HZ310_02280)	-	462704..463759 (-)	1056	WP_061409762.1	LCP family protein	-
HZ310_RS02285 (HZ310_02285)	-	463744..464412 (-)	669	WP_058013556.1	YigZ family protein	-
HZ310_RS02290 (HZ310_02290)	degS	464634..465809 (+)	1176	WP_024719243.1	sensor histidine kinase	Regulator
HZ310_RS02295 (HZ310_02295)	degU	465874..466563 (+)	690	WP_008348273.1	two-component system response regulator DegU	Regulator
HZ310_RS02300 (HZ310_02300)	-	466781..467623 (+)	843	WP_180310004.1	DegV family protein	-
HZ310_RS02305 (HZ310_02305)	comFA	467743..469122 (+)	1380	WP_306821882.1	DEAD/DEAH box helicase	Machinery gene
HZ310_RS02310 (HZ310_02310)	-	469189..469482 (+)	294	WP_180310005.1	late competence development ComFB family protein	-
HZ310_RS02315 (HZ310_02315)	comFC	469479..470165 (+)	687	WP_180310006.1	ComF family protein	Machinery gene
HZ310_RS02320 (HZ310_02320)	-	470222..470641 (+)	420	WP_034660147.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 391 a.a.
• Molecular weight: 45550.27 Da
• Isoelectric Point: 5.8757

>NTDB_id=466067 HZ310_RS02290 WP_024719243.1 464634..465809(+) (degS) [Bacillus pumilus strain UAMX]
MTTPKMDPKLLDSIIMKMLSTVDGSKDEVFRIGEQSRQQYESLVEELKQIKQQVNEVIDFGDKLEVHTRHARNRLSEVSR
NFNKFSEEEIREAYEKAHNLQVELTMIQQREKQLRERRDDLERRLLSLQDVIERSETLVSQITVVLNYLNQDLRQVGVLL
EDAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEEGFKEIRSLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLNTIEEYDGKTKITFQCLGDTENERIASQFEVALFRLAQEAVTNSLKHSEAEEISVKVEV
TKDFVTLIIKDDGKGFDMKDVKTNKNKSFGLLGMKERVDLLEGKMTIDSKIGLGTFIMIRVPLTLQNKIVK

Nucleotide

• Length: 1176 bp

>NTDB_id=466067 HZ310_RS02290 WP_024719243.1 464634..465809(+) (degS) [Bacillus pumilus strain UAMX]
ATGACAACACCTAAAATGGATCCGAAATTATTGGATTCAATCATCATGAAAATGCTAAGTACAGTTGATGGCAGCAAGGA
CGAAGTATTTAGGATAGGCGAACAGTCCCGTCAACAATATGAAAGCCTTGTAGAAGAGCTGAAGCAAATCAAACAGCAAG
TAAACGAAGTAATTGATTTTGGGGATAAACTAGAAGTCCATACGAGACATGCTAGAAATCGTTTATCTGAGGTCAGCAGA
AACTTCAACAAATTTAGCGAAGAAGAAATACGGGAGGCCTACGAAAAAGCACATAATCTGCAAGTGGAACTCACCATGAT
CCAGCAGCGCGAAAAGCAGCTGAGAGAAAGAAGAGACGATCTGGAAAGACGATTGTTAAGCCTGCAAGACGTCATTGAAC
GCTCTGAAACGCTTGTGAGCCAGATCACAGTGGTTCTCAACTATCTCAACCAGGACTTACGCCAAGTTGGCGTGTTACTT
GAAGATGCTCAAGCAAAACAAGATTTTGGACTTAGAATTATTGAAGCCCAAGAAGAAGAACGTAAAAGGGTATCCCGTGA
AATTCATGACGGTCCGGCACAGATGCTGGCGAACGTGATGATGCGCTCTGAATTAATTGAACGGATTTTCAGAGATCGTG
GGACAGAAGAAGGCTTTAAAGAAATTAGAAGTCTCAGACAGAATGTGCGAAATGCTCTGTACGAAGTGAGAAGAATCATT
TATGATTTAAGACCAATGGCTTTAGATGATTTGGGTCTCATTCCGACGCTAAGAAAATATTTAAACACAATCGAAGAGTA
TGATGGAAAAACCAAGATCACGTTCCAATGCCTAGGGGATACAGAAAATGAAAGAATTGCTTCTCAATTCGAAGTGGCAC
TGTTTAGACTAGCCCAAGAAGCTGTCACAAATTCATTGAAGCATTCCGAAGCTGAAGAAATCTCTGTAAAAGTAGAAGTG
ACGAAAGACTTTGTCACGTTAATTATCAAAGACGATGGAAAAGGCTTTGATATGAAAGATGTGAAAACAAACAAAAACAA
ATCCTTCGGTTTACTTGGCATGAAAGAACGCGTAGACTTACTGGAAGGTAAAATGACCATAGACTCAAAAATAGGTCTAG
GGACATTCATCATGATTCGCGTGCCATTAACATTGCAAAATAAAATTGTAAAATAG

Domains

Predicted by InterproScan.

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A0A081LEM4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	85.455	98.465	0.841