Detailed information    

insolico Bioinformatically predicted

Overview


Name   comEA   Type   Machinery gene
Locus tag   LPE509_RS11320 Genome accession   NC_020521
Coordinates   2547196..2547513 (-) Length   105 a.a.
NCBI ID   WP_010946546.1    Uniprot ID   Q5ZXC2
Organism   Legionella pneumophila subsp. pneumophila LPE509     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 2542196..2552513
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPE509_RS11300 (LPE509_02402) - 2543104..2543802 (-) 699 WP_010946551.1 hypothetical protein -
  LPE509_RS11305 (LPE509_02403) - 2544063..2544665 (+) 603 WP_015444719.1 pseudouridine synthase -
  LPE509_RS16040 mreD 2544601..2545080 (-) 480 WP_010946549.1 rod shape-determining protein MreD -
  LPE509_RS11310 (LPE509_02405) mreC 2545077..2545985 (-) 909 WP_010946548.1 rod shape-determining protein MreC -
  LPE509_RS11315 (LPE509_02406) - 2545963..2547000 (-) 1038 WP_011213320.1 rod shape-determining protein -
  LPE509_RS11320 (LPE509_02407) comEA 2547196..2547513 (-) 318 WP_010946546.1 helix-hairpin-helix domain-containing protein Machinery gene
  LPE509_RS11325 (LPE509_02408) - 2547605..2549020 (-) 1416 WP_010946545.1 M20 family metallopeptidase -
  LPE509_RS11330 (LPE509_02409) - 2548995..2550086 (-) 1092 WP_010946544.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  LPE509_RS11335 (LPE509_02410) nadC 2550083..2550925 (-) 843 WP_010946543.1 carboxylating nicotinate-nucleotide diphosphorylase -
  LPE509_RS11340 (LPE509_02411) - 2550922..2552361 (-) 1440 WP_010946542.1 cation:proton antiporter -

Sequence


Protein


Download         Length: 105 a.a.        Molecular weight: 11773.78 Da        Isoelectric Point: 10.5233

>NTDB_id=46445 LPE509_RS11320 WP_010946546.1 2547196..2547513(-) (comEA) [Legionella pneumophila subsp. pneumophila LPE509]
MKARLIAILLSFIVIPFSSQAENEPQKTPAKQVLVKGKINLNTADVYSLTGSFKGIGKKRAEAIIAYRENHQGFKSLEEL
AEVKGIGQRFVDKNREKLKEIFVIN

Nucleotide


Download         Length: 318 bp        

>NTDB_id=46445 LPE509_RS11320 WP_010946546.1 2547196..2547513(-) (comEA) [Legionella pneumophila subsp. pneumophila LPE509]
ATGAAAGCAAGACTCATTGCTATTTTATTGTCATTTATTGTTATCCCTTTCTCTTCTCAAGCTGAGAACGAGCCTCAAAA
AACTCCAGCTAAACAAGTCCTTGTTAAGGGCAAGATTAATCTTAATACAGCGGATGTGTATTCTTTAACAGGCTCTTTTA
AAGGGATAGGAAAAAAACGGGCTGAAGCTATTATTGCTTATAGAGAGAATCATCAAGGGTTTAAATCTCTGGAAGAGCTT
GCGGAAGTCAAGGGTATAGGGCAGCGTTTTGTAGATAAAAATAGAGAAAAACTGAAAGAAATTTTCGTTATTAATTAA

Domains


Predicted by InterProScan.

(37-98)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q5ZXC2

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Legionella pneumophila str. Paris

100

100

1

  comEA Legionella pneumophila strain ERS1305867

100

100

1

  comE1/comEA Haemophilus influenzae Rd KW20

35.455

100

0.371

  comEA Staphylococcus aureus N315

38.384

94.286

0.362

  comEA Staphylococcus aureus MW2

38.384

94.286

0.362


Multiple sequence alignment