Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   JM964_RS00320 Genome accession   NZ_CP068708
Coordinates   53448..54347 (+) Length   299 a.a.
NCBI ID   WP_012774888.1    Uniprot ID   -
Organism   Streptococcus suis strain ID33329     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 48448..59347
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JM964_RS10240 - 49147..49293 (+) 147 Protein_39 ATP-binding cassette domain-containing protein -
  JM964_RS00295 (JM964_00295) - 49384..50247 (+) 864 Protein_40 ABC transporter ATP-binding protein -
  JM964_RS00300 (JM964_00300) - 50349..50522 (+) 174 WP_014735240.1 hypothetical protein -
  JM964_RS00305 (JM964_00305) ruvB 50817..51818 (+) 1002 WP_024402117.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  JM964_RS00310 (JM964_00310) - 51818..52564 (+) 747 WP_024402116.1 GNAT family N-acetyltransferase -
  JM964_RS00315 (JM964_00315) - 52566..53201 (+) 636 WP_024402115.1 HAD-IA family hydrolase -
  JM964_RS00320 (JM964_00320) comR 53448..54347 (+) 900 WP_012774888.1 helix-turn-helix domain-containing protein Regulator
  JM964_RS00325 (JM964_00325) - 54983..55921 (-) 939 WP_024402114.1 IS4 family transposase -
  JM964_RS00330 (JM964_00330) - 56058..57272 (+) 1215 WP_029749649.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  JM964_RS00335 (JM964_00335) - 57469..58992 (+) 1524 WP_044763875.1 quinol oxidase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35405.30 Da        Isoelectric Point: 4.6492

>NTDB_id=460839 JM964_RS00320 WP_012774888.1 53448..54347(+) (comR) [Streptococcus suis strain ID33329]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=460839 JM964_RS00320 WP_012774888.1 53448..54347(+) (comR) [Streptococcus suis strain ID33329]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAATTCAAATGATTTATTTGTTTTACGAGACACGCTATTATCTTGCG
TAAATATATTAGGAAGCAAAAAATATTACGAACCAATACCAAAGATATTTGACAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
TGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAGAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterProScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

100

100

1
  comR Streptococcus suis 05ZYH33

100

100

1
  comR Streptococcus suis D9

62.126

100

0.625
  comR Streptococcus mutans UA159

43.813

100

0.438
  comR Streptococcus pyogenes MGAS315

37.374

99.331

0.371