Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   LILO_RS01900 Genome accession   NC_020450
Coordinates   385003..386445 (-) Length   480 a.a.
NCBI ID   WP_015425846.1    Uniprot ID   -
Organism   Lactococcus lactis subsp. lactis IO-1     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 380003..391445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LILO_RS01875 (lilo_0354) nox 380037..381377 (+) 1341 WP_015425842.1 H2O-forming NADH oxidase -
  LILO_RS01880 (lilo_0355) - 381466..381855 (+) 390 WP_015425843.1 single-stranded DNA-binding protein -
  LILO_RS01885 (lilo_0356) groES 381975..382259 (+) 285 WP_003131589.1 co-chaperone GroES -
  LILO_RS01890 (lilo_0357) groL 382347..383975 (+) 1629 WP_015425845.1 chaperonin GroEL -
  LILO_RS01895 (lilo_0358) vicX 384021..384833 (-) 813 WP_003131583.1 MBL fold metallo-hydrolase Regulator
  LILO_RS01900 (lilo_0359) vicK 385003..386445 (-) 1443 WP_015425846.1 sensor histidine kinase Regulator
  LILO_RS01905 (lilo_0360) yycF 386438..387139 (-) 702 WP_003131580.1 response regulator YycF -
  LILO_RS01910 (lilo_0361) tmk 387317..387952 (+) 636 WP_015425847.1 dTMP kinase -
  LILO_RS01915 (lilo_0362) - 388085..388945 (+) 861 WP_015425848.1 DNA polymerase III subunit delta' -
  LILO_RS01920 (lilo_0363) yaaT 388997..389779 (+) 783 WP_015425849.1 stage 0 sporulation family protein Regulator
  LILO_RS01925 (lilo_0364) yabA 389772..390098 (+) 327 WP_015425850.1 DNA replication initiation control protein YabA -
  LILO_RS01930 (lilo_0365) rsmI 390098..390973 (+) 876 WP_015425851.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  LILO_RS01935 (lilo_0366) - 391050..391241 (-) 192 WP_003131566.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54656.11 Da        Isoelectric Point: 4.5540

>NTDB_id=46067 LILO_RS01900 WP_015425846.1 385003..386445(-) (vicK) [Lactococcus lactis subsp. lactis IO-1]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKISDQYNFYDLLEKEPEITIETQDAGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=46067 LILO_RS01900 WP_015425846.1 385003..386445(-) (vicK) [Lactococcus lactis subsp. lactis IO-1]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGTGATAAAATC
CCAAAAGGGACGAGTGAAATCAATGAATTATACGATGAAATTTTAAAACTTGGTGAAGATATTGTTCGCACACAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATCCTCGCATATATGGTTGATGGCGTCATTGCCACCGACCGGCGCGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCACTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTCTTAAAAATTTCTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACAGGATGC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TTTTACATGATATGACTGAACAAGATAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCTATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACTCTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGAGAAAGTGATGTTCTAATCTCCATCAGTGACCAAGGAATGGGAATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGAACAGGTTTAGGCCTCTC
TATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGTTCTGAAGGAGAAGGAAAAGGAACTACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGCACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.559

86.875

0.448
  micB Streptococcus pneumoniae Cp1015

47.973

92.5

0.444

Multiple sequence alignment