Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   JJN14_RS08495 Genome accession   NZ_CP067992
Coordinates   1715313..1715945 (-) Length   210 a.a.
NCBI ID   WP_049509719.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V7-A3     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1710313..1720945
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJN14_RS08480 (JJN14_08480) lepB 1710722..1711336 (+) 615 WP_049486944.1 signal peptidase I -
  JJN14_RS08485 (JJN14_08485) recD/recD2/recDB 1711455..1713821 (+) 2367 WP_201058417.1 ATP-dependent RecD-like DNA helicase Machinery gene
  JJN14_RS08490 (JJN14_08490) tig 1713869..1715152 (-) 1284 WP_045612235.1 trigger factor -
  JJN14_RS08495 (JJN14_08495) vraR 1715313..1715945 (-) 633 WP_049509719.1 response regulator transcription factor Regulator
  JJN14_RS08500 (JJN14_08500) - 1715956..1716954 (-) 999 WP_201058418.1 sensor histidine kinase -
  JJN14_RS08505 (JJN14_08505) liaF 1716951..1717649 (-) 699 WP_070528777.1 cell wall-active antibiotics response protein LiaF -
  JJN14_RS08510 (JJN14_08510) fni 1717726..1718736 (-) 1011 WP_201058419.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  JJN14_RS08515 (JJN14_08515) - 1718720..1719727 (-) 1008 WP_201058420.1 phosphomevalonate kinase -
  JJN14_RS08520 (JJN14_08520) mvaD 1719714..1720667 (-) 954 WP_201058421.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23564.07 Da        Isoelectric Point: 4.9016

>NTDB_id=458257 JJN14_RS08495 WP_049509719.1 1715313..1715945(-) (vraR) [Streptococcus mitis strain S022-V7-A3]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEAANGSQGIDLALKLRPDVIVMDIVMPEINGIDATLAILKEWPEAKILIV
SSYLDNEKIMPVLDAGARGYMLKTSSADELLHAVRKAAAGELAIEQEVSKKVEYHRNHIELHEDLTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=458257 JJN14_RS08495 WP_049509719.1 1715313..1715945(-) (vraR) [Streptococcus mitis strain S022-V7-A3]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGTTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGCGAGGCGGCAAACGGGTCTCAAGGTATTGACTTGGCCTTGAAACTGCGTCCAGATGTCATTGTCATGGATA
TCGTTATGCCTGAGATAAATGGAATTGATGCGACCTTGGCTATCCTCAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
AGCTCTTATTTGGACAATGAAAAAATCATGCCCGTCTTAGATGCAGGTGCTCGTGGCTATATGCTTAAGACTTCTAGTGC
CGACGAACTGCTCCATGCTGTCCGTAAGGCGGCTGCTGGGGAGTTGGCCATTGAGCAAGAGGTCAGCAAAAAAGTCGAAT
ACCACCGCAATCACATAGAACTACATGAGGACCTGACTGCGCGTGAGCGAGATGTGCTCCAACTCATCGCTAAGGGCTAT
GAAAATCAGCGTATCGCAGACGAACTTTTCATCTCTCTCAAGACGGTCAAGACTCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGCACCCAGGCAGCGGTCTATGCCTTTCAGCACCACTTGGTGGGGCATGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-115)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.971

98.095

0.5
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41