Detailed information NTG0457504

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: HV560_RS05475
• Genome accession: NZ_CP055305
• Coordinates: 1101550..1102863 (-)
• Length: 437 a.a.
• NCBI ID: WP_176812332.1
• Uniprot ID: -
• Organism: Mannheimia pernigra strain 17CN0883
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1096550..1107863

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HV560_RS05445 (HV560_05445)	ruvB	1097179..1098183 (-)	1005	WP_176812328.1	Holliday junction branch migration DNA helicase RuvB	-
HV560_RS05450 (HV560_05450)	ruvA	1098194..1098796 (-)	603	WP_176812329.1	Holliday junction branch migration protein RuvA	-
HV560_RS05455 (HV560_05455)	-	1098905..1099531 (-)	627	WP_159629280.1	LysE family transporter	-
HV560_RS05460 (HV560_05460)	-	1099525..1100007 (-)	483	WP_176808048.1	phosphatidylglycerophosphatase A	-
HV560_RS05465 (HV560_05465)	thiL	1100013..1100993 (-)	981	WP_176812330.1	thiamine-phosphate kinase	-
HV560_RS05470 (HV560_05470)	nusB	1101057..1101470 (-)	414	WP_176812331.1	transcription antitermination factor NusB	-
HV560_RS05475 (HV560_05475)	comE	1101550..1102863 (-)	1314	WP_176812332.1	type IV pilus secretin PilQ	Machinery gene
HV560_RS05480 (HV560_05480)	-	1102872..1103282 (-)	411	WP_176812333.1	hypothetical protein	-
HV560_RS05485 (HV560_05485)	-	1103284..1103817 (-)	534	WP_176812334.1	hypothetical protein	-
HV560_RS05490 (HV560_05490)	-	1103819..1104340 (-)	522	WP_176812335.1	hypothetical protein	-
HV560_RS05495 (HV560_05495)	-	1104316..1105023 (-)	708	WP_176812336.1	competence protein ComA	-
HV560_RS05500 (HV560_05500)	-	1105150..1107699 (+)	2550	WP_176812337.1	penicillin-binding protein 1A	-

Sequence

Protein

• Length: 437 a.a.
• Molecular weight: 48427.66 Da
• Isoelectric Point: 8.9535

>NTDB_id=457504 HV560_RS05475 WP_176812332.1 1101550..1102863(-) (comE) [Mannheimia pernigra strain 17CN0883]
MFRIFLFLFISSSLAFANTISLAVKNAPTATILTYLSEEIGKNIVLDDNIQTKSTLRLENKSIDDIFKVISTMNKLSLHQ
EGDVIYISKKEEKLTDLKTIPIAHLQNNIENTPLVTTPKLITKTIKLHYAKASEVIESLTKGSGTFLSENGYIHFDERSN
SLIIKDSTKSLQHIEKLVKQLDQPTEQIAIEARIVTISSEHLQELGVRWGMFSKGADHYKFGGRLESNGLSNVANNLNVS
FPVTNGASAVLQVASINSRVLDLELSALEQENSVEIIASPRLLTTNKKPASIKQGTEIPYVMYNKKSEATNVEFKEAVLG
LEVIPHLSTENQILLDLIVTQNSPNSQSGSSGLVTIDKQELNTQVFAKHGETIVLGGVFQHLTQKGEDKVPILGSIPFIK
RLFSQTRDKISKRELVIFVTPYIIQSNEKLGGVKKSK

Nucleotide

• Length: 1314 bp

>NTDB_id=457504 HV560_RS05475 WP_176812332.1 1101550..1102863(-) (comE) [Mannheimia pernigra strain 17CN0883]
ATGTTTAGAATTTTTCTTTTTTTATTTATTAGCTCCTCATTAGCATTTGCTAACACAATTTCTCTTGCTGTGAAAAATGC
ACCCACTGCAACCATTTTGACTTATTTATCCGAAGAAATAGGAAAAAATATTGTTTTAGATGATAATATTCAAACAAAAT
CAACATTAAGATTAGAAAATAAATCCATTGACGATATATTCAAAGTAATAAGCACAATGAATAAATTATCGCTACATCAA
GAAGGTGATGTTATTTATATCAGTAAAAAAGAAGAAAAATTGACCGATTTAAAAACAATTCCAATCGCTCATTTGCAAAA
TAATATAGAAAATACACCGCTTGTTACCACACCCAAACTCATTACTAAAACAATAAAACTACATTATGCTAAAGCCTCAG
AAGTGATTGAATCTTTAACAAAAGGCAGCGGTACTTTTTTATCTGAAAATGGCTATATCCATTTTGATGAGCGAAGTAAT
AGTTTAATTATCAAAGACAGTACAAAATCACTTCAACACATAGAAAAGTTAGTTAAACAGCTTGACCAACCAACTGAGCA
AATTGCAATTGAAGCACGCATTGTCACAATCAGCAGTGAACATTTACAAGAATTGGGGGTGCGTTGGGGAATGTTCTCAA
AAGGGGCTGATCACTATAAATTTGGTGGGCGACTTGAAAGTAACGGATTAAGCAATGTTGCTAATAATCTCAATGTGAGT
TTTCCTGTTACGAATGGTGCTTCAGCAGTTTTACAAGTCGCTTCTATTAATAGCCGAGTACTGGATCTGGAATTGAGTGC
CTTAGAGCAAGAAAATAGTGTAGAAATTATCGCCAGCCCTCGCCTTTTGACTACGAATAAAAAACCAGCGAGTATCAAAC
AAGGTACAGAAATTCCTTATGTGATGTACAATAAAAAATCGGAAGCTACTAATGTGGAATTTAAAGAAGCCGTGCTGGGC
TTAGAAGTTATTCCTCATCTTTCGACTGAAAATCAAATATTACTCGATCTGATTGTTACTCAAAATTCTCCTAATTCGCA
ATCAGGCAGTAGTGGCTTAGTGACTATTGATAAACAAGAATTGAATACACAAGTTTTTGCGAAACACGGCGAAACGATCG
TTTTAGGCGGAGTTTTCCAACATTTAACGCAAAAAGGAGAAGATAAAGTACCTATTTTAGGTTCAATTCCGTTTATCAAA
CGCTTATTCAGCCAAACTCGAGATAAAATTAGCAAAAGAGAACTTGTGATTTTTGTTACCCCTTACATTATTCAATCAAA
TGAAAAATTAGGTGGTGTGAAAAAATCAAAATAG

Domains

Predicted by InterproScan.

• Bacterial type II/III secretion system short domain (Secretin_N) (122-187)

• Bacterial type II and III secretion system protein (Secretin) (267-425)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Glaesserella parasuis strain SC1401	61.609	99.542	0.613
comE	Haemophilus influenzae Rd KW20	49.206	100	0.497
comE	Haemophilus influenzae 86-028NP	48.98	100	0.494
pilQ	Vibrio cholerae O1 biovar El Tor strain E7946	39.623	97.025	0.384
pilQ	Vibrio cholerae strain A1552	39.623	97.025	0.384
pilQ	Vibrio campbellii strain DS40M4	38.462	98.169	0.378