Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   JCR30_RS00920 Genome accession   NZ_CP067008
Coordinates   145970..146398 (+) Length   142 a.a.
NCBI ID   WP_002986548.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain iGAS426     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 140970..151398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JCR30_RS00900 (JCR30_00900) - 143301..143666 (+) 366 WP_002986560.1 DUF1033 family protein -
  JCR30_RS00905 (JCR30_00905) comGA 143759..144697 (+) 939 WP_011888534.1 competence type IV pilus ATPase ComGA Machinery gene
  JCR30_RS00910 (JCR30_00910) comGB 144633..145667 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  JCR30_RS00915 (JCR30_00915) comGC 145669..145995 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  JCR30_RS00920 (JCR30_00920) comGD 145970..146398 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  JCR30_RS00925 (JCR30_00925) comGE 146355..146639 (+) 285 WP_041174183.1 competence type IV pilus minor pilin ComGE Machinery gene
  JCR30_RS00930 (JCR30_00930) comGF 146632..147066 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  JCR30_RS00935 (JCR30_00935) comGG 147050..147376 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  JCR30_RS00940 (JCR30_00940) comGH 147474..148427 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  JCR30_RS00945 (JCR30_00945) - 148486..149682 (+) 1197 WP_011888536.1 acetate kinase -
  JCR30_RS00950 (JCR30_00950) - 149869..150177 (+) 309 WP_011017251.1 hypothetical protein -
  JCR30_RS00955 (JCR30_00955) proC 150260..151030 (-) 771 WP_002986527.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16310.04 Da        Isoelectric Point: 10.3481

>NTDB_id=456748 JCR30_RS00920 WP_002986548.1 145970..146398(+) (comGD) [Streptococcus pyogenes strain iGAS426]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=456748 JCR30_RS00920 WP_002986548.1 145970..146398(+) (comGD) [Streptococcus pyogenes strain iGAS426]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366