Detailed information NTG0456742

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: JCR30_RS00580
• Genome accession: NZ_CP067008
• Coordinates: 93943..94941 (+)
• Length: 332 a.a.
• NCBI ID: WP_002986679.1
• Uniprot ID: A2RC05
• Organism: Streptococcus pyogenes strain iGAS426
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 88943..99941

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JCR30_RS00560 (JCR30_00560)	-	89951..91369 (+)	1419	WP_011888524.1	hypothetical protein	-
JCR30_RS00565 (JCR30_00565)	purB	91389..92681 (+)	1293	WP_011888525.1	adenylosuccinate lyase	-
JCR30_RS00570 (JCR30_00570)	comR	92812..93723 (+)	912	WP_011888526.1	XRE family transcriptional regulator	Regulator
JCR30_RS00575 (JCR30_00575)	comS	93814..93912 (+)	99	WP_020833188.1	quorum-sensing system DWW-type pheromone	Regulator
JCR30_RS00580 (JCR30_00580)	ruvB	93943..94941 (+)	999	WP_002986679.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
JCR30_RS00585 (JCR30_00585)	-	95079..95516 (+)	438	WP_002994668.1	low molecular weight phosphotyrosine protein phosphatase	-
JCR30_RS00590 (JCR30_00590)	-	95539..95940 (+)	402	WP_011017240.1	MORN repeat-containing protein	-
JCR30_RS00595 (JCR30_00595)	-	95937..97712 (+)	1776	WP_011888527.1	acyltransferase family protein	-

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37565.11 Da
• Isoelectric Point: 5.3005

>NTDB_id=456742 JCR30_RS00580 WP_002986679.1 93943..94941(+) (ruvB) [Streptococcus pyogenes strain iGAS426]
MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIIT
AQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQK
AYRHLGYPYQNT

Nucleotide

• Length: 999 bp

>NTDB_id=456742 JCR30_RS00580 WP_002986679.1 93943..94941(+) (ruvB) [Streptococcus pyogenes strain iGAS426]
ATGGCTAGAATTTTAGACAATAATGTAATGGGAAATGAGGAGTTTTCGGATCGGACTCTTCGCCCTCAATATCTACACGA
ATATATTGGACAAGATAAAGTTAAGGAACAATTCGCTATTTTTATAGAAGCAGCTAAAAGACGTGACGAATCTTTAGACC
ATGTTTTATTATTTGGACCTCCAGGACTGGGAAAAACAACAATGGCATTTGTGATTGCCAATGAATTGGGAGTTAATTTA
AAGCAAACTTCAGGTCCTGCCGTTGAGAAAGCTGGAGATTTGGTAGCTATTTTAAATGAATTAGAACCAGGGGATATTTT
GTTTATTGATGAAATTCACCGCATGCCAATGTCTGTCGAGGAAGTACTATATAGTGCTATGGAAGACTTCTATATTGATA
TTATGATTGGCGCTGGAGATACTAGTCGTAGTATTCATTTGGATCTGCCTCCATTTACATTGATTGGTGCTACTACACGT
GCAGGCATGTTATCTAATCCCCTCAGAGCTCGTTTTGGTATCACTGGTCACATGGAATACTATCAAGAAAAGGATTTGAC
AGAGATTGTGGAGCGTACAGCTACTATTTTTGAAATAAAAATAGACCATGAAGCTGCACGGAAATTAGCTTGTCGCAGTA
GAGGAACGCCCCGCATTGCTAATCGATTACTAAAACGAGTGCGTGACTATGCTCAAATTATTGGTGATGGCATCATAACG
GCTCAAATAACTGATAGAGCTTTGACTATGTTAGATGTTGACCGCGAAGGTCTCGATTACATTGATCAGAAAATTTTACG
AACGATGATTGAGATGTATCAGGGAGGACCAGTTGGTTTGGGGACATTATCTGTGAATATTGCCGAGGAGCGTAATACAG
TTGAAGAGATGTATGAACCCTACTTAATTCAAAAAGGCTTTCTCATGCGAACACGAACAGGTCGTGTAGCGACTCAAAAG
GCTTATCGTCATCTTGGCTATCCCTATCAAAACACTTAA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

3D structure

• AlphaFold DB: A2RC05

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae D39	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae TIGR4	84.545	99.398	0.84
ruvB	Bacillus subtilis subsp. subtilis str. 168	58.824	97.289	0.572
ruvB	Helicobacter pylori 26695	48.936	99.096	0.485
ruvB	Synechocystis sp. PCC 6803	50.16	94.277	0.473