Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   JF649_RS06475 Genome accession   NZ_CP066541
Coordinates   1288811..1289476 (-) Length   221 a.a.
NCBI ID   WP_063632027.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain MGAS270     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1283811..1294476
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JF649_RS06470 (JF649_06450) raiA 1288183..1288731 (-) 549 WP_002988974.1 ribosome-associated translation inhibitor RaiA -
  JF649_RS06475 (JF649_06455) comFC/cflB 1288811..1289476 (-) 666 WP_063632027.1 ComF family protein Machinery gene
  JF649_RS06480 (JF649_06460) comFA/cflA 1289448..1290773 (-) 1326 WP_032465157.1 DEAD/DEAH box helicase Machinery gene
  JF649_RS06485 (JF649_06465) - 1290829..1291461 (+) 633 WP_032465870.1 YigZ family protein -
  JF649_RS06490 (JF649_06470) cysK 1291589..1292530 (+) 942 WP_009880467.1 cysteine synthase A -
  JF649_RS06495 (JF649_06475) - 1292548..1292925 (-) 378 WP_002983674.1 S1 RNA-binding domain-containing protein -
  JF649_RS06500 (JF649_06480) - 1292925..1294325 (-) 1401 WP_115354026.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25175.47 Da        Isoelectric Point: 9.4626

>NTDB_id=455189 JF649_RS06475 WP_063632027.1 1288811..1289476(-) (comFC/cflB) [Streptococcus pyogenes strain MGAS270]
MICLLCQQISQIPISITEIIFLRRISSPICQQCQKSFQKIGKSVCATCCANSDIIACRDCLKWENKGYNVNHRSLYCYNA
AMKAYFSQYKFQGDYLLRKVFAVELADVITKYYKGYIPVPVPVSPGCFRERQFNQVSAILEAANVSYLSLFEKLDNTHQS
SRTKKERLLVEKSYRLLKVSNIPDKILIVDDIYTTGSTIIALRKQLAKVANSDIKSLSIAR

Nucleotide


Download         Length: 666 bp        

>NTDB_id=455189 JF649_RS06475 WP_063632027.1 1288811..1289476(-) (comFC/cflB) [Streptococcus pyogenes strain MGAS270]
ATGATCTGTCTACTATGTCAACAAATTAGTCAAATACCAATAAGTATTACAGAAATCATCTTTTTAAGGCGTATCTCTTC
ACCGATTTGTCAACAATGTCAAAAAAGCTTTCAAAAGATAGGAAAAAGTGTTTGTGCGACATGTTGTGCAAACTCAGATA
TAATAGCTTGTCGAGATTGTCTAAAATGGGAAAACAAAGGATACAATGTAAATCATAGAAGCTTATATTGTTATAATGCT
GCTATGAAAGCATACTTCAGTCAATATAAGTTTCAAGGAGACTATTTATTAAGAAAAGTTTTTGCAGTAGAACTTGCCGA
TGTTATTACCAAGTACTATAAAGGCTATATCCCAGTCCCGGTTCCTGTAAGTCCCGGTTGTTTTCGAGAAAGACAATTTA
ATCAAGTGAGCGCTATTCTTGAGGCAGCTAATGTTAGCTACCTTTCTCTTTTTGAAAAGCTAGATAATACTCACCAATCT
TCCAGAACAAAAAAAGAGAGATTATTAGTAGAAAAATCTTATCGACTACTAAAAGTATCAAACATTCCTGATAAAATCCT
TATAGTAGATGATATTTATACTACTGGTAGTACAATTATCGCTCTTAGAAAACAATTGGCTAAAGTAGCAAATAGTGACA
TTAAAAGTTTGTCAATTGCACGTTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus mitis SK321

41.629

100

0.416
  comFC/cflB Streptococcus pneumoniae Rx1

41.176

100

0.412
  comFC/cflB Streptococcus pneumoniae D39

41.176

100

0.412
  comFC/cflB Streptococcus pneumoniae R6

41.176

100

0.412
  comFC/cflB Streptococcus mitis NCTC 12261

41.176

100

0.412
  comFC/cflB Streptococcus pneumoniae TIGR4

41.176

100

0.412