Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   I6H74_RS07560 Genome accession   NZ_CP066069
Coordinates   1543504..1545288 (-) Length   594 a.a.
NCBI ID   WP_115256863.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1017     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1538504..1550288
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H74_RS07535 (I6H74_07530) pepV 1539354..1540763 (-) 1410 WP_046177065.1 dipeptidase PepV -
  I6H74_RS07540 (I6H74_07535) - 1540941..1541543 (-) 603 WP_003054310.1 nitroreductase family protein -
  I6H74_RS10915 - 1541856..1543451 (+) 1596 Protein_1435 thiamine pyrophosphate-dependent enzyme -
  I6H74_RS07560 (I6H74_07555) uvrC 1543504..1545288 (-) 1785 WP_115256863.1 excinuclease ABC subunit UvrC Machinery gene
  I6H74_RS07565 (I6H74_07560) - 1545418..1545567 (-) 150 WP_115256862.1 HAD hydrolase family protein -
  I6H74_RS07570 (I6H74_07565) - 1545623..1546999 (-) 1377 WP_115256861.1 NAD-dependent succinate-semialdehyde dehydrogenase -
  I6H74_RS07575 (I6H74_07570) - 1547077..1547784 (-) 708 WP_015017084.1 YjjG family noncanonical pyrimidine nucleotidase -
  I6H74_RS10920 - 1547832..1548197 (-) 366 WP_232619972.1 DUF1524 domain-containing protein -
  I6H74_RS07585 (I6H74_07580) - 1548720..1549286 (-) 567 Protein_1441 sugar O-acetyltransferase -
  I6H74_RS07590 (I6H74_07585) - 1549302..1549802 (-) 501 WP_046177072.1 HAD family hydrolase -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68080.82 Da        Isoelectric Point: 9.4002

>NTDB_id=453573 I6H74_RS07560 WP_115256863.1 1543504..1545288(-) (uvrC) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNTEALLLEIN
LIQENMPKYNIKLKDDKSYPFIKITNETFPRLLITRQIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPVNKVCF
YYHLGQCCAHTICHTDKAYWDGLVEDVKHFLNGKDDKIIDGLRAKMLAASEEMAFERAAEYRDLISGIAIMRTKQRVMSK
DLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNLFPYYNEAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAI
VPTKIIKPKRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIDNLGYLLGIDKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVVGPDDYASMREVIFRRYSRVKHEGLVAPDLIIIDGGLGQVNAAREVIEDRLGLTIPIVGLQ
KNDKHQTHELLFGKPLEVVPLPRNSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDKIPGLGPKRKQILLKHFKTM
TAIAAASPDEIHSLGIPRAVASAVHQHLTDSQQS

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=453573 I6H74_RS07560 WP_115256863.1 1543504..1545288(-) (uvrC) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGAATGAACTGATTAAACACAAGCTAGAACTCTTGCCAGATAGTCCTGGTTGTTACTTGCATAAGGACAAAGAGGGAAC
CATTATCTATGTAGGTAAAGCTAAGAATTTGAAGAACCGAGTGCGGTCTTATTTTCGTGGTAGCCATGATACCAAGACAG
AATTATTGGTGTCTGAGATTGCTGATTTTGAATTTATTGTGACCGAATCAAATACTGAGGCACTCTTGCTTGAAATCAAC
TTGATTCAAGAAAACATGCCCAAATATAATATCAAGCTCAAAGATGACAAGTCTTATCCTTTTATCAAAATCACCAATGA
GACCTTTCCTCGCCTGCTTATTACGAGACAGATTAAGAAAAATGACGGTCTATATTTCGGGCCCTATCCAGATTCGTACA
CCGCTAACGAAGTGAAAAAATTGCTGGATCGCATTTTTCCCTTTAAGAAATGTAAAAACCCTGTCAATAAGGTCTGTTTT
TATTACCATTTAGGACAGTGTTGTGCTCATACTATCTGCCATACAGATAAGGCTTATTGGGATGGTCTGGTAGAGGATGT
CAAACACTTTTTGAATGGTAAGGATGACAAGATTATTGATGGGCTGCGGGCAAAAATGTTAGCAGCTTCTGAAGAAATGG
CATTTGAACGTGCCGCTGAATATCGAGATTTGATTTCAGGTATTGCCATCATGCGCACCAAGCAGCGGGTGATGAGTAAG
GACTTGCAAGACAGAGATATTTTTGGCTACTTTGTTGACAAGGGCTGGATGTGCGTACAGGTTTTCTTTGTCCGTCAAGG
GAAATTAATTCAGCGGGATGTTAACCTTTTTCCTTACTATAACGAGGCAGAAGAAGATTTTTTAACCTATATGGGGCAGT
TTTATCAAGATAAACAGCATTTCATCCCCAAAGAAGTCTTTATTCCAGAAGCTATTGACGAAGAATTAGTAGCCGCTATT
GTACCAACAAAAATCATCAAACCAAAACGGGGTGAGAAAAAACAATTGGTGGCTTTGGCGACCAAGAATGCACGTGTTAG
CCTTCAGCAGAAATTTGATTTGTTGGAAAAAGATATTAAGAAAACTAGCGGTGCCATTGACAATCTAGGCTACTTGTTAG
GAATTGACAAGCCAGTCCGGATTGAGGCTTTTGATAATTCCAATATTCAAGGGACAAGCCCCGTAGCGGCTATGGTTGTT
TTTGTTGACGGGAAACCTAGTAAGAAAGATTATCGTAAATTTAAGATTAAAACAGTGGTGGGCCCAGATGATTATGCCAG
CATGAGGGAAGTGATTTTTCGAAGGTATAGCCGCGTTAAACATGAAGGATTGGTTGCTCCTGATTTAATCATCATTGATG
GTGGGCTAGGGCAAGTCAATGCGGCCAGAGAAGTGATTGAAGACCGACTAGGTTTAACGATTCCTATTGTGGGCTTGCAA
AAAAATGATAAGCACCAGACCCATGAATTGCTCTTTGGCAAGCCACTCGAGGTAGTCCCCTTACCCCGTAATTCAGAAGA
ATTTTTCCTCTTGCATCGCATCCAAGATGAGGTGCACCGCTTTGCGATTACTTTCCACCGACAGGTTCGCAGTAAAAATT
CATTCTCTTCGAAATTGGATAAGATTCCAGGACTAGGTCCGAAGCGCAAGCAGATACTGCTTAAACATTTTAAAACCATG
ACAGCCATTGCAGCAGCTAGTCCAGATGAGATTCATTCGTTAGGGATTCCTAGGGCGGTGGCATCAGCTGTCCATCAGCA
TCTGACAGACAGTCAGCAAAGTTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(373-523)

UvrB/uvrC motif (UVR)

(196-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

75.552

99.158

0.749
  uvrC Streptococcus pneumoniae R6

75.212

99.158

0.746
  uvrC Streptococcus pneumoniae D39

75.212

99.158

0.746