Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   I6H74_RS03465 Genome accession   NZ_CP066069
Coordinates   691801..692583 (+) Length   260 a.a.
NCBI ID   WP_003053880.1    Uniprot ID   A0A9X9SKT8
Organism   Streptococcus dysgalactiae strain FDAARGOS_1017     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 686801..697583
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H74_RS03445 (I6H74_03440) - 686944..687909 (-) 966 WP_115257002.1 asparaginase -
  I6H74_RS03450 (I6H74_03445) - 687982..689370 (+) 1389 WP_003052568.1 Cof-type HAD-IIB family hydrolase -
  I6H74_RS03455 (I6H74_03450) - 689533..689985 (-) 453 WP_003052566.1 universal stress protein -
  I6H74_RS03460 (I6H74_03455) - 690322..691536 (+) 1215 WP_046176867.1 pyridoxal phosphate-dependent aminotransferase -
  I6H74_RS03465 (I6H74_03460) codY 691801..692583 (+) 783 WP_003053880.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  I6H74_RS03470 (I6H74_03465) - 692721..693272 (+) 552 WP_172601569.1 isochorismatase family cysteine hydrolase -
  I6H74_RS03475 (I6H74_03470) - 693339..693599 (-) 261 WP_003053835.1 metal-sensitive transcriptional regulator -
  I6H74_RS03480 (I6H74_03475) - 693813..694151 (+) 339 WP_046176894.1 rhodanese-like domain-containing protein -
  I6H74_RS03485 (I6H74_03480) - 694169..695821 (+) 1653 WP_003059881.1 FAD-dependent oxidoreductase -
  I6H74_RS03490 (I6H74_03485) - 695814..696113 (+) 300 WP_065957237.1 rhodanese-like domain-containing protein -
  I6H74_RS03495 (I6H74_03490) - 696374..696937 (+) 564 WP_343237547.1 CBS domain-containing protein -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28748.89 Da        Isoelectric Point: 4.4678

>NTDB_id=453543 I6H74_RS03465 WP_003053880.1 691801..692583(+) (codY) [Streptococcus dysgalactiae strain FDAARGOS_1017]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVESELTIFPVESKDIYPDGLTTIAPIYGGGMRLGSLIIWRNDNEFSDEDLILVEISSTVVGIQLLN
LQTENLEETIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFDKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=453543 I6H74_RS03465 WP_003053880.1 691801..692583(+) (codY) [Streptococcus dysgalactiae strain FDAARGOS_1017]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATTACGTCTATTCTACAGCGCTCTGTAGATAGCTTGGAGACAGAACTCCC
ATATAATACGATGGCGTCTCGCTTGGCAGATATTATTGACTGTAATGCCTGCATTATCAATGGCGGAGGAACCCTACTTG
GTTATGCCATGAAATATAAAACCAACACAGACCGTGTTGAGGAATTTTTTGAAGCTAAGCAATTTCCAGATACTTATGTC
AAAGCAGCTAGCCGTGTCTACGACACTGAGGCCAATCTTTCAGTGGAAAGTGAATTAACCATTTTTCCTGTGGAATCGAA
AGACATCTATCCAGATGGTTTGACAACAATTGCACCGATTTATGGTGGAGGTATGCGTCTAGGATCTCTTATCATTTGGC
GCAACGATAATGAGTTTAGTGATGAGGACCTCATCTTGGTTGAAATTTCAAGCACGGTTGTTGGGATTCAGTTGTTAAAC
CTTCAAACAGAAAACCTGGAAGAAACGATCCGCAAGCAAACTGCTGTCAACATGGCTATTAACACCCTATCTTATTCAGA
AATGAAGGCTGTTGCAGCTATTCTTGGTGAATTGGATGGTAACGAAGGGCGTTTAACAGCTTCTGTCATTGCTGACCGTA
TTGGCATTACACGATCTGTGATCGTCAATGCCCTTCGTAAATTGGAAAGTGCTGGTATTATTGAAAGTCGCTCTCTCGGC
ATGAAGGGAACCTACCTCAAAGTTATTAATGAGGGTATTTTTGATAAATTGAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9X9SKT8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.537

98.846

0.658
  codY Bacillus subtilis subsp. subtilis str. 168

53.036

95

0.504