Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FOC72_RS05615 Genome accession   NZ_CP054570
Coordinates   1151040..1152431 (-) Length   463 a.a.
NCBI ID   WP_002895754.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain FDAARGOS_770     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1146040..1157431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC72_RS05595 (FOC72_05595) - 1146943..1148034 (+) 1092 WP_002895743.1 DEAD/DEAH box helicase -
  FOC72_RS05600 (FOC72_05600) - 1148127..1149524 (-) 1398 WP_002895744.1 polysaccharide deacetylase family protein -
  FOC72_RS05605 (FOC72_05605) - 1149586..1149972 (-) 387 WP_002895748.1 VOC family protein -
  FOC72_RS05610 (FOC72_05610) - 1150086..1151024 (-) 939 WP_002895751.1 ketopantoate reductase family protein -
  FOC72_RS05615 (FOC72_05615) ciaH 1151040..1152431 (-) 1392 WP_002895754.1 cell wall metabolism sensor histidine kinase WalK Regulator
  FOC72_RS05620 (FOC72_05620) ciaR 1152421..1153095 (-) 675 WP_002895755.1 response regulator transcription factor Regulator
  FOC72_RS05625 (FOC72_05625) - 1153200..1153679 (-) 480 WP_002895756.1 hypothetical protein -
  FOC72_RS05630 (FOC72_05630) - 1153986..1156526 (-) 2541 WP_002895758.1 M1 family metallopeptidase -
  FOC72_RS05635 (FOC72_05635) - 1156695..1157021 (-) 327 WP_002895760.1 hypothetical protein -
  FOC72_RS05640 (FOC72_05640) - 1157030..1157326 (-) 297 WP_002895761.1 hypothetical protein -

Sequence

Protein


Download         Length: 463 a.a.        Molecular weight: 52613.05 Da        Isoelectric Point: 8.4934

>NTDB_id=453497 FOC72_RS05615 WP_002895754.1 1151040..1152431(-) (ciaH) [Streptococcus sanguinis strain FDAARGOS_770]
MLNKIKKTFYADDFSYFIRYFGLFTLIFSAMTLIIIQVMRSSLYTSVDENLKNLSNDPSSVADLAYRTTGQQSDPSNKVN
SKSPKSSKEPDGDSDEEPKPNNLTTPNVSSNTFALLLDDDYKNISTSKSDGFLDFNSLEFNKSYLNQIKEIVIGNSFGQT
ESYRAYLFDIDPKNEYPDIKYAVVMTSISQLEQTSSKHEQLIAMVMVSFWGISLIASIYLARMSVKPLLESIQKQKAFVE
NASHELRTPLAVLQSRLETLFRKPEATIMQSSENIASSLDEVRNMRLLTTNLLNLARRDDGIKPQYGEVEPEFFDTTFAN
YCIIARENKKAFHSENMIKHPIVTDQIFLKQLMTILFDNAIKYTDDDGVISVMATSTDRYLIFRVADNGPGISDEDKKKI
FDRFYRVDKARTRQKGGFGLGLSLAKQIVDAFKGSIYVKDNKPKGTVFEVKLLLKETKKRPVK

Nucleotide


Download         Length: 1392 bp        

>NTDB_id=453497 FOC72_RS05615 WP_002895754.1 1151040..1152431(-) (ciaH) [Streptococcus sanguinis strain FDAARGOS_770]
ATGCTGAATAAAATCAAGAAGACCTTTTATGCGGATGATTTCTCTTATTTCATTCGCTATTTTGGGTTGTTTACATTAAT
CTTCTCAGCCATGACCTTGATTATTATTCAGGTTATGCGCTCCAGCCTTTATACGTCAGTTGATGAAAATCTGAAAAACC
TGAGTAATGATCCTAGTTCAGTAGCTGATTTGGCCTATCGGACGACAGGTCAGCAGTCTGATCCGAGCAATAAGGTCAAT
TCTAAAAGTCCTAAAAGCAGTAAAGAGCCAGATGGTGATTCAGATGAAGAGCCTAAGCCTAACAATCTAACTACGCCAAA
TGTCAGCTCTAATACTTTTGCCCTGCTTTTGGATGATGATTATAAAAATATTTCCACCAGCAAGAGCGATGGTTTTCTGG
ACTTTAACTCGCTGGAATTTAACAAGTCCTATCTGAATCAAATCAAGGAAATCGTGATTGGTAATAGCTTTGGCCAGACA
GAAAGCTATCGGGCTTATCTCTTTGATATTGATCCTAAAAATGAGTATCCTGATATCAAGTATGCTGTGGTCATGACTAG
TATCAGCCAGCTGGAGCAGACCAGCAGCAAGCATGAGCAGTTGATTGCCATGGTTATGGTCAGTTTTTGGGGAATTTCCC
TGATTGCCAGTATTTACCTTGCTCGGATGAGTGTCAAGCCTCTGCTGGAAAGTATCCAGAAGCAGAAGGCTTTCGTGGAA
AATGCCAGCCATGAGCTGCGGACACCTTTGGCTGTTTTGCAGAGCCGCTTAGAAACGCTCTTTCGTAAGCCTGAAGCAAC
AATCATGCAGAGCAGTGAAAATATCGCTTCTAGCTTGGATGAAGTGCGCAATATGCGCTTGCTGACGACTAATCTGCTCA
ATCTGGCCCGTCGCGATGATGGCATCAAGCCTCAATATGGTGAAGTTGAACCAGAATTTTTTGATACGACCTTTGCTAAT
TACTGTATTATCGCAAGGGAGAATAAAAAAGCCTTTCATTCAGAAAATATGATCAAGCACCCTATTGTGACCGATCAAAT
TTTTCTCAAACAACTGATGACTATTCTATTTGATAATGCTATCAAGTATACAGATGATGATGGCGTAATCAGTGTCATGG
CTACTTCGACAGATCGCTACCTTATTTTCCGAGTAGCGGACAATGGCCCTGGTATCAGTGATGAAGATAAGAAGAAGATT
TTTGATCGCTTTTATCGGGTGGACAAGGCTCGGACTCGTCAGAAAGGTGGCTTTGGTCTGGGACTTTCTCTGGCCAAGCA
GATTGTCGATGCTTTCAAAGGCTCTATTTATGTCAAGGACAACAAACCAAAAGGTACGGTCTTTGAAGTTAAACTGCTAT
TGAAAGAAACGAAAAAGCGCCCTGTTAAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(236-301)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(344-454)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

60.738

99.568

0.605
  ciaH Streptococcus pneumoniae D39

60.738

99.568

0.605
  ciaH Streptococcus pneumoniae R6

60.738

99.568

0.605
  ciaH Streptococcus pneumoniae TIGR4

60.738

99.568

0.605
  ciaH Streptococcus mutans UA159

53.289

98.488

0.525