Detailed information NTG0452752

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: HT132_RS03715
• Genome accession: NZ_CP054479
• Coordinates: 701298..702461 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus amyloliquefaciens strain R8-25
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 696298..707461

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HT132_RS03695 (HT132_03695)	-	696704..697900 (+)	1197	WP_174532387.1	glycosyltransferase	-
HT132_RS03700 (HT132_03700)	-	698033..699109 (+)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
HT132_RS03705 (HT132_03705)	-	699209..700423 (-)	1215	WP_022553868.1	LCP family protein	-
HT132_RS03710 (HT132_03710)	-	700428..701075 (-)	648	WP_007407485.1	YigZ family protein	-
HT132_RS03715 (HT132_03715)	degS	701298..702461 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
HT132_RS03720 (HT132_03720)	degU	702538..703227 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
HT132_RS03725 (HT132_03725)	-	703325..704173 (+)	849	WP_003151387.1	DegV family protein	-
HT132_RS03730 (HT132_03730)	comFA	704281..705666 (+)	1386	WP_174532388.1	DEAD/DEAH box helicase	Machinery gene
HT132_RS03735 (HT132_03735)	-	705724..706008 (+)	285	WP_045209016.1	competence protein ComFB	-
HT132_RS03740 (HT132_03740)	comFC	706014..706703 (+)	690	WP_202729384.1	phosphoribosyltransferase family protein	Machinery gene
HT132_RS03745 (HT132_03745)	-	706777..707196 (+)	420	WP_061861586.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=452752 HT132_RS03715 WP_007407484.1 701298..702461(+) (degS) [Bacillus amyloliquefaciens strain R8-25]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=452752 HT132_RS03715 WP_007407484.1 701298..702461(+) (degS) [Bacillus amyloliquefaciens strain R8-25]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTGGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGGTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGATGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951