NTDB

Overview

Name	ruvA	Type	Machinery gene
Locus tag	JAN99_RS08640	Genome accession	NZ_CP065927
Coordinates	1779312..1779908 (-)	Length	198 a.a.
NCBI ID	WP_038434336.1	Uniprot ID	-
Organism	Streptococcus pyogenes strain emm9ST603
Function	homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1774312..1784908

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JAN99_RS08605 (JAN99_08600)	-	1774367..1774672 (-)	306	WP_002982199.1	DUF1292 domain-containing protein	-
JAN99_RS08610 (JAN99_08605)	ruvX	1774684..1775103 (-)	420	WP_111693462.1	Holliday junction resolvase RuvX	-
JAN99_RS08615 (JAN99_08610)	-	1775100..1775369 (-)	270	WP_002982194.1	IreB family regulatory phosphoprotein	-
JAN99_RS08620 (JAN99_08615)	spx	1775488..1775886 (-)	399	WP_002982188.1	transcriptional regulator Spx	-
JAN99_RS08625 (JAN99_08620)	recA	1776177..1777313 (-)	1137	WP_023612576.1	recombinase RecA	Machinery gene
JAN99_RS08630 (JAN99_08625)	cinA	1777402..1778673 (-)	1272	WP_111693463.1	competence/damage-inducible protein A	Machinery gene
JAN99_RS08635 (JAN99_08630)	-	1778742..1779302 (-)	561	WP_011018314.1	DNA-3-methyladenine glycosylase I	-
JAN99_RS08640 (JAN99_08635)	ruvA	1779312..1779908 (-)	597	WP_038434336.1	Holliday junction branch migration protein RuvA	Machinery gene
JAN99_RS08645 (JAN99_08640)	-	1779910..1781130 (-)	1221	WP_085634351.1	MFS transporter	-
JAN99_RS08650 (JAN99_08645)	hexB	1781141..1783123 (-)	1983	WP_136116212.1	DNA mismatch repair endonuclease MutL	Machinery gene
JAN99_RS08655 (JAN99_08650)	-	1783218..1784363 (-)	1146	WP_021299091.1	site-specific integrase	-
JAN99_RS09215 (JAN99_08655)	-	1784691..1784834 (+)	144	WP_011185066.1	putative holin-like toxin	-

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21834.16 Da Isoelectric Point: 6.4948

                                >NTDB_id=452067 JAN99_RS08640 WP_038434336.1 1779312..1779908(-) (ruvA) [Streptococcus pyogenes strain emm9ST603]

MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI

GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGHTKARSNKAGNTQLDEAIEAL

LALGYKAAELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide

Download Length: 597 bp

                                >NTDB_id=452067 JAN99_RS08640 WP_038434336.1 1779312..1779908(-) (ruvA) [Streptococcus pyogenes strain emm9ST603]

ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAACAAATGGACTAGGCTATAT

TATCAATGTAGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG

AGGATGCTCACTTGTTGTTTGGGTTTCATACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT

GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA

GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG

CTCCACAAGAGACTGGTCATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC

CTTGCCCTCGGTTATAAGGCAGCGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATA

CATCAAATCAGCCCTTAAACTATTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA N terminal domain (RuvA_N)

(1-61)

RuvA, C-terminal domain (RuvA_C)

(152-196)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ruvA	Streptococcus pneumoniae TIGR4	67.005	99.495	0.667
ruvA	Streptococcus pneumoniae R6	67.005	99.495	0.667
ruvA	Streptococcus pneumoniae D39	67.005	99.495	0.667
ruvA	Bacillus subtilis subsp. subtilis str. 168	40.394	100	0.414

Detailed information NTG0452067