Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   JAN99_RS02060 Genome accession   NZ_CP065927
Coordinates   403087..403869 (+) Length   260 a.a.
NCBI ID   WP_002983278.1    Uniprot ID   A2RCV3
Organism   Streptococcus pyogenes strain emm9ST603     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 398087..408869
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JAN99_RS02040 (JAN99_02035) - 398424..399389 (-) 966 WP_002983258.1 asparaginase -
  JAN99_RS02045 (JAN99_02040) - 399461..400849 (+) 1389 WP_009881044.1 Cof-type HAD-IIB family hydrolase -
  JAN99_RS02050 (JAN99_02045) - 400972..401424 (-) 453 WP_002992571.1 universal stress protein -
  JAN99_RS02055 (JAN99_02050) - 401655..402869 (+) 1215 WP_011184883.1 pyridoxal phosphate-dependent aminotransferase -
  JAN99_RS02060 (JAN99_02055) codY 403087..403869 (+) 783 WP_002983278.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  JAN99_RS02065 (JAN99_02060) - 404016..404570 (+) 555 WP_136116012.1 isochorismatase family cysteine hydrolase -
  JAN99_RS02070 (JAN99_02065) - 405047..405349 (+) 303 Protein_357 putative PEP-binding protein -
  JAN99_RS02075 (JAN99_02070) gatC 405581..405883 (+) 303 WP_111693359.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
  JAN99_RS02080 (JAN99_02075) gatA 405883..407349 (+) 1467 WP_003053823.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
  JAN99_RS02085 (JAN99_02080) gatB 407349..408788 (+) 1440 WP_003052542.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=452011 JAN99_RS02060 WP_002983278.1 403087..403869(+) (codY) [Streptococcus pyogenes strain emm9ST603]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=452011 JAN99_RS02060 WP_002983278.1 403087..403869(+) (codY) [Streptococcus pyogenes strain emm9ST603]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACATTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAGTTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAATTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAACGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A2RCV3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504