Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   HRE60_RS05525 Genome accession   NZ_CP054153
Coordinates   1149342..1150757 (-) Length   471 a.a.
NCBI ID   WP_181670388.1    Uniprot ID   -
Organism   Streptococcus salivarius strain DB-B5     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1144342..1155757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HRE60_RS05495 (HRE60_05495) - 1144971..1145369 (-) 399 WP_021144038.1 cytidine deaminase -
  HRE60_RS05500 (HRE60_05500) deoC 1145356..1146018 (-) 663 WP_021144037.1 deoxyribose-phosphate aldolase -
  HRE60_RS05505 (HRE60_05505) - 1146052..1147329 (-) 1278 WP_181670386.1 pyrimidine-nucleoside phosphorylase -
  HRE60_RS05510 (HRE60_05510) - 1147326..1147916 (-) 591 WP_045768632.1 class I SAM-dependent methyltransferase -
  HRE60_RS05515 (HRE60_05515) coaA 1148029..1148949 (+) 921 WP_181670387.1 type I pantothenate kinase -
  HRE60_RS05520 (HRE60_05520) rpsT 1149019..1149255 (+) 237 WP_004182129.1 30S ribosomal protein S20 -
  HRE60_RS05525 (HRE60_05525) ciaH 1149342..1150757 (-) 1416 WP_181670388.1 HAMP domain-containing sensor histidine kinase Regulator
  HRE60_RS05530 (HRE60_05530) ciaR 1150747..1151421 (-) 675 WP_002891134.1 response regulator transcription factor Regulator
  HRE60_RS05535 (HRE60_05535) - 1151620..1153290 (-) 1671 WP_004182072.1 formate--tetrahydrofolate ligase -
  HRE60_RS05540 (HRE60_05540) - 1153484..1154167 (+) 684 WP_181670389.1 phosphopantothenate--cysteine ligase -
  HRE60_RS05545 (HRE60_05545) coaC 1154160..1154705 (+) 546 WP_004182014.1 phosphopantothenoylcysteine decarboxylase -
  HRE60_RS05550 (HRE60_05550) - 1154734..1155306 (+) 573 WP_181670390.1 ECF transporter S component -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53542.24 Da        Isoelectric Point: 8.1737

>NTDB_id=451170 HRE60_RS05525 WP_181670388.1 1149342..1150757(-) (ciaH) [Streptococcus salivarius strain DB-B5]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKESTTETSDSSDSKKEPKKKSKIEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVGRSIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=451170 HRE60_RS05525 WP_181670388.1 1149342..1150757(-) (ciaH) [Streptococcus salivarius strain DB-B5]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTCTTTGCTAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTGCAGATTCTGAGTTATGGCGTTTATTCCAATGTGGATTCTA
GTCTGAAAATGGCAGCAACTAAGACCAATTCTTATTTAGAAATGGAAATGCTCAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACAACCATTTACCAAGCCTATGATACTAAAGAGTCGACAACTGAAACATCTGACTCGAGTGA
CTCTAAAAAAGAACCTAAGAAGAAATCGAAGATAGAAGATGCTCCTCACGATTTATCAGTTGCGGCAAATACCAGTGTTT
TGGTACTTGATAAGAATGGAAAAGTCCTTAATGTCGTTGATAAATTTTCAAGCTTATCCAATTTACCAATAGATAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACGGAAAAGTATCGCCTGATCACTGAGAAAGT
AGACAATAGTCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCAACTGAACGTT
ATGTCAAGCTAATTGTCATCATGATGAGTTTCTTCTGGCTCTTATCTGTTGCGGCTAGTATGTATTTGGCCAAGTGGTCA
AGACGTCCTATTCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAGAATGCTAGCCATGAGTTACGGACACCGCTTGC
TGTGATTCAAAACAGATTAGAAGTTCTTTTCCGCAAGCCTGAGAGCACCATTCTAGATAATTCAGAGAATATTGCTTCAA
GTCTTGATGAAGTACGCAACATGCGTCTTTTGACGACTAATCTTTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTCTTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAACCAAGTTGGTCGTTCAATCCAGACTGATAAAACGTTATTGAAACAGTTAATGACCATCTTATTTG
ATAATGCTATTAAATATACGGAAGATGACGGACATGTTACCTTTACTGTCCGCACTAATGACCGCCATCTTTATATTTCT
GTAGCTGATAATGGTCCTGGAATATCAGATAGTGATAAGAAAAAAATCTTTGATCGCTTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTTTAGCCCTTAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAAATTACTGGAGTTTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.522

97.665

0.552
  ciaH Streptococcus pneumoniae Rx1

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae D39

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae R6

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae TIGR4

50.216

98.514

0.495