Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   I6G22_RS04225 Genome accession   NZ_CP065737
Coordinates   777921..779363 (+) Length   480 a.a.
NCBI ID   WP_012897229.1    Uniprot ID   -
Organism   Lactococcus lactis strain FDAARGOS_865     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 772921..784363
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G22_RS04190 (I6G22_04195) - 773125..773316 (+) 192 WP_012897234.1 hypothetical protein -
  I6G22_RS04195 (I6G22_04200) rsmI 773393..774268 (-) 876 WP_003131568.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  I6G22_RS04200 (I6G22_04205) yabA 774268..774594 (-) 327 WP_011675472.1 DNA replication initiation control protein YabA -
  I6G22_RS04205 (I6G22_04210) yaaT 774587..775369 (-) 783 WP_025016551.1 stage 0 sporulation family protein Regulator
  I6G22_RS04210 (I6G22_04215) - 775421..776281 (-) 861 WP_012897231.1 DNA polymerase III subunit delta' -
  I6G22_RS04215 (I6G22_04220) tmk 776414..777049 (-) 636 WP_012897230.1 dTMP kinase -
  I6G22_RS04220 (I6G22_04225) yycF 777227..777928 (+) 702 WP_003131580.1 response regulator YycF -
  I6G22_RS04225 (I6G22_04230) vicK 777921..779363 (+) 1443 WP_012897229.1 sensor histidine kinase Regulator
  I6G22_RS04230 (I6G22_04235) vicX 779532..780344 (+) 813 WP_003131583.1 MBL fold metallo-hydrolase Regulator
  I6G22_RS04235 (I6G22_04240) groL 780390..782018 (-) 1629 WP_023188993.1 chaperonin GroEL -
  I6G22_RS04240 (I6G22_04245) groES 782107..782391 (-) 285 WP_003131589.1 co-chaperone GroES -
  I6G22_RS04245 (I6G22_04250) - 782511..782900 (-) 390 WP_023188994.1 single-stranded DNA-binding protein -
  I6G22_RS04250 (I6G22_04255) nox 782990..784330 (-) 1341 WP_023188995.1 H2O-forming NADH oxidase -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54649.12 Da        Isoelectric Point: 4.5889

>NTDB_id=451003 I6G22_RS04225 WP_012897229.1 777921..779363(+) (vicK) [Lactococcus lactis strain FDAARGOS_865]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKIADQYNFYDLLEKEPEITIETHDAGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=451003 I6G22_RS04225 WP_012897229.1 777921..779363(+) (vicK) [Lactococcus lactis strain FDAARGOS_865]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATACTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGCGATAAAATC
CCAAAAGGGACGAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTTGGTGAAGATATTGTTCGCACACAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCATTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTGCTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACATGATGC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACACTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGATGTTCTAATCTCCATCAGTGACCAAGGAATGGGAATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGGACAGGTTTAGGCCTCTC
CATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGCTCCGAAGGAGAAGGAAAAGGAACGACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGCACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.559

86.875

0.448
  micB Streptococcus pneumoniae Cp1015

47.748

92.5

0.442