Detailed information NTG0450984

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: I6G22_RS02465
• Genome accession: NZ_CP065737
• Coordinates: 439710..441080 (-)
• Length: 456 a.a.
• NCBI ID: WP_023189696.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain FDAARGOS_865
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 434710..446080

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G22_RS02450 (I6G22_02450)	-	435882..437315 (-)	1434	WP_023189694.1	6-phospho-beta-glucosidase	-
I6G22_RS02455 (I6G22_02455)	yidD	437437..437703 (-)	267	WP_010906087.1	membrane protein insertion efficiency factor YidD	-
I6G22_RS02460 (I6G22_02460)	-	437820..439562 (-)	1743	WP_025016942.1	1-deoxy-D-xylulose-5-phosphate synthase	-
I6G22_RS02465 (I6G22_02465)	ciaH	439710..441080 (-)	1371	WP_023189696.1	sensor histidine kinase	Regulator
I6G22_RS02470 (I6G22_02470)	ciaR	441173..441841 (-)	669	WP_211279595.1	response regulator transcription factor	Regulator
I6G22_RS02475 (I6G22_02475)	-	442019..442993 (-)	975	WP_025016944.1	LacI family DNA-binding transcriptional regulator	-
I6G22_RS02480 (I6G22_02480)	-	443146..445401 (-)	2256	WP_025016945.1	glycoside hydrolase family 65 protein	-

Sequence

Protein

• Length: 456 a.a.
• Molecular weight: 51301.84 Da
• Isoelectric Point: 9.3138

>NTDB_id=450984 I6G22_RS02465 WP_023189696.1 439710..441080(-) (ciaH) [Lactococcus lactis strain FDAARGOS_865]
MKKIIKKVKSSAIVKNDGKNFLHFFLAFTVIFVALAVIIIQVMQLGMYRATDQNLHNLAQNRVFLIEAANNQLGMNNSQD
SGYYGPNNSVIFYDSEGKSFIPSAGSNANISTDFGMSLLQKTMKFNENQINTIQTVSVKNPYGDNWHYRYLTTSQFIITN
TDGTVTPVYAQIFSNVDQIQDAMSRAMWVIVTTMITFWLLSVIISLYLANWTLKPILAAYEKQKEFVENASHELRTPLAI
LQNRLELLFQKPTATIIDESENISESLSEVRNMRLLTSNLLNLARRDSGIRIEPEATTATYFENIFNSYEMLAENAGKKF
SGHLKLDGTINLDQALIKQLLTILFDNALKYTGDEGEISVDVQKNGGFLVFAVADNGEGISDEDKKKIFDRFFRVDKART
RQKGGLGLGLSLAKQIVEAYNGKITVEDNKPKGTKFIVRIRVDSTISNPAKIFQKL

Nucleotide

• Length: 1371 bp

>NTDB_id=450984 I6G22_RS02465 WP_023189696.1 439710..441080(-) (ciaH) [Lactococcus lactis strain FDAARGOS_865]
TTGAAGAAAATAATTAAAAAAGTTAAATCTTCAGCTATTGTAAAAAATGATGGGAAAAATTTCCTTCATTTTTTTCTAGC
TTTTACAGTCATTTTTGTTGCTTTAGCCGTGATTATTATTCAAGTCATGCAATTAGGAATGTATCGAGCGACTGACCAAA
ATTTACACAATTTGGCTCAAAACCGAGTCTTTTTGATAGAAGCAGCGAATAATCAATTAGGAATGAATAATTCGCAAGAT
AGTGGCTATTACGGTCCCAATAATAGTGTAATTTTTTATGATTCAGAGGGTAAAAGTTTCATACCTTCAGCGGGTTCAAA
TGCAAATATAAGTACAGACTTTGGCATGAGCCTTCTGCAAAAAACAATGAAATTTAACGAAAATCAAATTAACACTATTC
AAACTGTTTCTGTAAAAAATCCTTATGGAGATAATTGGCACTATCGTTATCTGACAACATCACAATTTATTATTACAAAT
ACTGATGGAACAGTAACTCCGGTTTATGCACAAATTTTTTCAAATGTTGACCAAATTCAAGATGCCATGAGCCGAGCCAT
GTGGGTCATTGTGACAACAATGATTACTTTCTGGCTTCTGTCAGTAATTATTAGTCTATATCTTGCAAACTGGACATTAA
AACCAATTTTGGCCGCTTATGAAAAACAAAAAGAATTTGTTGAAAATGCTTCACATGAATTGAGAACACCTCTGGCAATC
TTGCAAAATCGTCTAGAATTACTTTTCCAAAAGCCAACAGCAACAATTATTGATGAATCAGAAAATATTTCTGAAAGTTT
ATCAGAAGTTCGTAATATGCGTTTATTAACAAGTAACTTACTGAACTTAGCTCGTCGAGATTCTGGAATCAGAATTGAGC
CAGAGGCGACTACGGCAACTTATTTTGAGAATATTTTTAATAGCTATGAAATGCTTGCTGAAAACGCAGGTAAAAAGTTT
TCAGGCCATTTGAAATTAGATGGAACGATTAATTTGGACCAAGCCCTGATCAAACAATTGCTAACCATATTATTTGATAA
TGCTCTTAAATACACGGGTGATGAGGGTGAAATCTCTGTAGATGTTCAAAAAAATGGGGGATTCTTAGTTTTTGCTGTCG
CCGATAATGGTGAAGGAATTTCTGATGAAGATAAGAAAAAAATCTTTGACCGCTTTTTCCGAGTAGATAAAGCAAGAACG
CGTCAAAAAGGTGGCTTAGGTTTGGGTCTTTCTCTGGCCAAACAAATTGTTGAAGCTTACAATGGGAAGATTACAGTTGA
AGATAATAAACCTAAAGGTACAAAATTCATTGTTAGAATTCGTGTGGATAGCACAATTTCAAATCCTGCAAAAATTTTCC
AAAAGTTGTAA

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (333-442)

• His Kinase A (phospho-acceptor) domain (HisKA) (223-289)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	48.14	94.298	0.454
ciaH	Streptococcus pneumoniae Rx1	44.543	98.465	0.439
ciaH	Streptococcus pneumoniae D39	44.543	98.465	0.439
ciaH	Streptococcus pneumoniae R6	44.543	98.465	0.439
ciaH	Streptococcus pneumoniae TIGR4	44.543	98.465	0.439