Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | FOC62_RS01945 | Genome accession | NZ_CP054017 |
| Coordinates | 354790..355659 (+) | Length | 289 a.a. |
| NCBI ID | WP_002450563.1 | Uniprot ID | - |
| Organism | Staphylococcus warneri strain FDAARGOS_754 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 322680..390105 | 354790..355659 | within | 0 |
Gene organization within MGE regions
Location: 322680..390105
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FOC62_RS01810 (FOC62_01815) | rsgA | 323697..324572 (+) | 876 | WP_002450588.1 | ribosome small subunit-dependent GTPase A | - |
| FOC62_RS01815 (FOC62_01820) | rpe | 324573..325217 (+) | 645 | WP_002450587.1 | ribulose-phosphate 3-epimerase | - |
| FOC62_RS01820 (FOC62_01825) | - | 325224..325862 (+) | 639 | WP_002450586.1 | thiamine diphosphokinase | - |
| FOC62_RS01825 (FOC62_01830) | rpmB | 325947..326135 (-) | 189 | WP_002435210.1 | 50S ribosomal protein L28 | - |
| FOC62_RS01830 (FOC62_01835) | - | 326443..326817 (+) | 375 | WP_002450585.1 | Asp23/Gls24 family envelope stress response protein | - |
| FOC62_RS01835 (FOC62_01840) | fakA | 326832..328481 (+) | 1650 | WP_002450584.1 | fatty acid kinase catalytic subunit FakA | - |
| FOC62_RS01840 (FOC62_01845) | recG | 328739..330787 (+) | 2049 | WP_002450583.1 | ATP-dependent DNA helicase RecG | - |
| FOC62_RS01845 (FOC62_01850) | fapR | 330936..331505 (+) | 570 | WP_002450582.1 | transcription factor FapR | - |
| FOC62_RS01850 (FOC62_01855) | plsX | 331498..332484 (+) | 987 | WP_002450581.1 | phosphate acyltransferase PlsX | - |
| FOC62_RS01855 (FOC62_01860) | fabD | 332477..333397 (+) | 921 | WP_002450580.1 | ACP S-malonyltransferase | - |
| FOC62_RS01860 (FOC62_01865) | fabG | 333397..334131 (+) | 735 | WP_002450579.1 | 3-oxoacyl-[acyl-carrier-protein] reductase | - |
| FOC62_RS01865 (FOC62_01870) | - | 334650..334883 (+) | 234 | WP_001830184.1 | acyl carrier protein | - |
| FOC62_RS01870 (FOC62_01875) | rnc | 334994..335725 (+) | 732 | WP_002450578.1 | ribonuclease III | - |
| FOC62_RS01875 (FOC62_01880) | smc | 335876..339445 (+) | 3570 | WP_002450577.1 | chromosome segregation protein SMC | - |
| FOC62_RS01880 (FOC62_01885) | ftsY | 339442..340686 (+) | 1245 | WP_002450576.1 | signal recognition particle-docking protein FtsY | - |
| FOC62_RS01885 (FOC62_01890) | - | 340673..341005 (+) | 333 | WP_002450575.1 | putative DNA-binding protein | - |
| FOC62_RS01890 (FOC62_01895) | ffh | 341030..342397 (+) | 1368 | WP_002450574.1 | signal recognition particle protein | - |
| FOC62_RS01895 (FOC62_01900) | rpsP | 342918..343193 (+) | 276 | WP_002450573.1 | 30S ribosomal protein S16 | - |
| FOC62_RS01900 (FOC62_01905) | rimM | 343362..343865 (+) | 504 | WP_002450572.1 | ribosome maturation factor RimM | - |
| FOC62_RS01905 (FOC62_01910) | trmD | 343865..344602 (+) | 738 | WP_002450571.1 | tRNA (guanosine(37)-N1)-methyltransferase TrmD | - |
| FOC62_RS01910 (FOC62_01915) | rplS | 344708..345058 (+) | 351 | WP_002450570.1 | 50S ribosomal protein L19 | - |
| FOC62_RS01915 (FOC62_01920) | - | 345220..347829 (-) | 2610 | WP_002450569.1 | YfhO family protein | - |
| FOC62_RS01920 (FOC62_01925) | - | 347822..350422 (-) | 2601 | WP_002450568.1 | YfhO family protein | - |
| FOC62_RS01925 (FOC62_01930) | ylqF | 350723..351598 (+) | 876 | WP_002450567.1 | ribosome biogenesis GTPase YlqF | - |
| FOC62_RS01930 (FOC62_01935) | - | 351591..352361 (+) | 771 | WP_002450566.1 | ribonuclease HII | - |
| FOC62_RS01935 (FOC62_01940) | sucC | 352469..353635 (+) | 1167 | WP_002450565.1 | ADP-forming succinate--CoA ligase subunit beta | - |
| FOC62_RS01940 (FOC62_01945) | sucD | 353657..354562 (+) | 906 | WP_002450564.1 | succinate--CoA ligase subunit alpha | - |
| FOC62_RS01945 (FOC62_01950) | dprA | 354790..355659 (+) | 870 | WP_002450563.1 | DNA-processing protein DprA | Machinery gene |
| FOC62_RS01950 (FOC62_01955) | topA | 355837..357912 (+) | 2076 | WP_171970108.1 | type I DNA topoisomerase | - |
| FOC62_RS01955 (FOC62_01960) | trmFO | 358029..359336 (+) | 1308 | WP_002450561.1 | FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO | - |
| FOC62_RS01960 (FOC62_01965) | xerC | 359501..360394 (+) | 894 | WP_002450560.1 | tyrosine recombinase XerC | - |
| FOC62_RS01965 (FOC62_01970) | hslV | 360391..360936 (+) | 546 | WP_002450559.1 | ATP-dependent protease subunit HslV | - |
| FOC62_RS01970 (FOC62_01975) | hslU | 361024..362427 (+) | 1404 | WP_002450558.1 | ATP-dependent protease ATPase subunit HslU | - |
| FOC62_RS01975 (FOC62_01980) | codY | 362451..363224 (+) | 774 | WP_002450557.1 | GTP-sensing pleiotropic transcriptional regulator CodY | - |
| FOC62_RS01980 (FOC62_01985) | rpsB | 363532..364320 (+) | 789 | WP_002450556.1 | 30S ribosomal protein S2 | - |
| FOC62_RS01985 (FOC62_01990) | tsf | 364472..365350 (+) | 879 | WP_002450555.1 | translation elongation factor Ts | - |
| FOC62_RS01990 (FOC62_01995) | pyrH | 365491..366213 (+) | 723 | WP_002450554.1 | UMP kinase | - |
| FOC62_RS01995 (FOC62_02000) | frr | 366229..366783 (+) | 555 | WP_002450553.1 | ribosome recycling factor | - |
| FOC62_RS02000 (FOC62_02005) | - | 367017..367787 (+) | 771 | WP_002450552.1 | isoprenyl transferase | - |
| FOC62_RS02005 (FOC62_02010) | - | 367791..368573 (+) | 783 | WP_002450551.1 | phosphatidate cytidylyltransferase | - |
| FOC62_RS02010 (FOC62_02015) | rseP | 368814..370100 (+) | 1287 | WP_002450550.1 | RIP metalloprotease RseP | - |
| FOC62_RS02015 (FOC62_02020) | - | 370120..371823 (+) | 1704 | WP_002450549.1 | proline--tRNA ligase | - |
| FOC62_RS02020 (FOC62_02025) | - | 372090..376400 (+) | 4311 | WP_100066973.1 | PolC-type DNA polymerase III | - |
| FOC62_RS02025 (FOC62_02030) | rimP | 376583..377050 (+) | 468 | WP_002450547.1 | ribosome maturation factor RimP | - |
| FOC62_RS02030 (FOC62_02035) | nusA | 377071..378303 (+) | 1233 | WP_002450546.1 | transcription termination factor NusA | - |
| FOC62_RS02035 (FOC62_02040) | - | 378323..378610 (+) | 288 | WP_002450545.1 | YlxR family protein | - |
| FOC62_RS02040 (FOC62_02045) | - | 378607..378924 (+) | 318 | WP_002450544.1 | ribosomal L7Ae/L30e/S12e/Gadd45 family protein | - |
| FOC62_RS02045 (FOC62_02050) | infB | 378929..381094 (+) | 2166 | WP_002450543.1 | translation initiation factor IF-2 | - |
| FOC62_RS02050 (FOC62_02055) | rbfA | 381234..381584 (+) | 351 | WP_002450542.1 | 30S ribosome-binding factor RbfA | - |
| FOC62_RS02055 (FOC62_02060) | truB | 381735..382652 (+) | 918 | WP_002450541.1 | tRNA pseudouridine(55) synthase TruB | - |
| FOC62_RS02060 (FOC62_02065) | ribF | 382665..383636 (+) | 972 | WP_002450540.1 | riboflavin biosynthesis protein RibF | - |
| FOC62_RS02065 (FOC62_02070) | rpsO | 383750..384019 (+) | 270 | WP_002450539.1 | 30S ribosomal protein S15 | - |
| FOC62_RS02070 (FOC62_02075) | pnp | 384155..386254 (+) | 2100 | WP_172852385.1 | polyribonucleotide nucleotidyltransferase | - |
| FOC62_RS02075 (FOC62_02080) | - | 386441..388114 (+) | 1674 | WP_002450536.1 | ribonuclease J | - |
Sequence
Protein
Download Length: 289 a.a. Molecular weight: 33757.90 Da Isoelectric Point: 8.6568
>NTDB_id=450182 FOC62_RS01945 WP_002450563.1 354790..355659(+) (dprA) [Staphylococcus warneri strain FDAARGOS_754]
MNEYFLLKLYWSQFTTSQIHQFYRYYPHIFQMTPKEQETSLLCWITHHHPMFLSKFHKYKQINIQEIMKILRQLHVKYIT
CFDQGYPHLLKEIYDYPLVLFYKGDEKLFLSSQTLAIVGSRKCTHYTQEALHFLFPSFKDKNITIISGLAEGADSEAHIQ
ALKNHLPTIAVLGFGHHYYYPRSSVSLRNRIEKEGLVISEYPPFSPIAKYKFPERNRIISGLSKGVLLTEANERSGSRIT
IDCALEQNRNVYVLPGKLFDSKTKGNLLLHQEGATIVVSEEDILQDYLN
MNEYFLLKLYWSQFTTSQIHQFYRYYPHIFQMTPKEQETSLLCWITHHHPMFLSKFHKYKQINIQEIMKILRQLHVKYIT
CFDQGYPHLLKEIYDYPLVLFYKGDEKLFLSSQTLAIVGSRKCTHYTQEALHFLFPSFKDKNITIISGLAEGADSEAHIQ
ALKNHLPTIAVLGFGHHYYYPRSSVSLRNRIEKEGLVISEYPPFSPIAKYKFPERNRIISGLSKGVLLTEANERSGSRIT
IDCALEQNRNVYVLPGKLFDSKTKGNLLLHQEGATIVVSEEDILQDYLN
Nucleotide
Download Length: 870 bp
>NTDB_id=450182 FOC62_RS01945 WP_002450563.1 354790..355659(+) (dprA) [Staphylococcus warneri strain FDAARGOS_754]
TTGAACGAATACTTTTTACTTAAATTATACTGGTCGCAATTTACAACCTCTCAAATCCATCAATTCTATCGGTACTACCC
ACATATTTTCCAAATGACTCCTAAAGAACAAGAAACGTCATTATTATGCTGGATAACACATCATCATCCTATGTTTCTTT
CTAAATTTCATAAATATAAACAAATAAATATACAAGAAATTATGAAAATTCTTCGACAATTACATGTAAAATATATCACT
TGTTTCGACCAAGGTTATCCACATTTATTAAAAGAAATCTATGATTATCCATTAGTTCTATTTTATAAAGGAGATGAAAA
GCTATTTTTAAGTAGTCAAACTCTAGCCATAGTTGGGTCTAGGAAATGTACACATTATACTCAAGAAGCGCTTCATTTTC
TTTTTCCTTCATTTAAAGATAAAAATATTACAATCATTTCTGGACTAGCAGAAGGCGCTGATAGTGAAGCACACATACAA
GCATTGAAAAATCATTTACCAACCATTGCAGTACTAGGTTTTGGACACCATTATTATTATCCTAGATCCTCGGTTTCATT
AAGAAATCGGATTGAAAAAGAGGGGTTAGTCATTTCAGAATATCCACCTTTTTCGCCAATTGCTAAATATAAATTTCCAG
AAAGAAATAGGATTATTAGTGGTTTGTCAAAAGGTGTATTACTAACTGAGGCAAACGAAAGAAGTGGTAGCAGAATTACA
ATTGATTGTGCATTAGAACAAAATAGAAACGTGTATGTTTTACCAGGTAAATTATTTGATTCCAAAACAAAAGGCAATTT
ATTATTACACCAAGAAGGGGCTACTATAGTCGTTAGTGAAGAAGATATTTTACAAGACTATTTAAATTGA
TTGAACGAATACTTTTTACTTAAATTATACTGGTCGCAATTTACAACCTCTCAAATCCATCAATTCTATCGGTACTACCC
ACATATTTTCCAAATGACTCCTAAAGAACAAGAAACGTCATTATTATGCTGGATAACACATCATCATCCTATGTTTCTTT
CTAAATTTCATAAATATAAACAAATAAATATACAAGAAATTATGAAAATTCTTCGACAATTACATGTAAAATATATCACT
TGTTTCGACCAAGGTTATCCACATTTATTAAAAGAAATCTATGATTATCCATTAGTTCTATTTTATAAAGGAGATGAAAA
GCTATTTTTAAGTAGTCAAACTCTAGCCATAGTTGGGTCTAGGAAATGTACACATTATACTCAAGAAGCGCTTCATTTTC
TTTTTCCTTCATTTAAAGATAAAAATATTACAATCATTTCTGGACTAGCAGAAGGCGCTGATAGTGAAGCACACATACAA
GCATTGAAAAATCATTTACCAACCATTGCAGTACTAGGTTTTGGACACCATTATTATTATCCTAGATCCTCGGTTTCATT
AAGAAATCGGATTGAAAAAGAGGGGTTAGTCATTTCAGAATATCCACCTTTTTCGCCAATTGCTAAATATAAATTTCCAG
AAAGAAATAGGATTATTAGTGGTTTGTCAAAAGGTGTATTACTAACTGAGGCAAACGAAAGAAGTGGTAGCAGAATTACA
ATTGATTGTGCATTAGAACAAAATAGAAACGTGTATGTTTTACCAGGTAAATTATTTGATTCCAAAACAAAAGGCAATTT
ATTATTACACCAAGAAGGGGCTACTATAGTCGTTAGTGAAGAAGATATTTTACAAGACTATTTAAATTGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Staphylococcus aureus N315 |
56.597 |
99.654 |
0.564 |
| dprA | Staphylococcus aureus MW2 |
56.597 |
99.654 |
0.564 |
| dprA/cilB/dalA | Streptococcus mitis SK321 |
36.082 |
100 |
0.363 |
| dprA/cilB/dalA | Streptococcus pneumoniae Rx1 |
36.082 |
100 |
0.363 |
| dprA/cilB/dalA | Streptococcus pneumoniae D39 |
36.082 |
100 |
0.363 |
| dprA/cilB/dalA | Streptococcus pneumoniae R6 |
36.082 |
100 |
0.363 |
| dprA/cilB/dalA | Streptococcus pneumoniae TIGR4 |
36.082 |
100 |
0.363 |