Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   FOC73_RS01445 Genome accession   NZ_CP053998
Coordinates   313637..315052 (-) Length   471 a.a.
NCBI ID   WP_037604990.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_771     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 308637..320052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC73_RS01415 (FOC73_01415) - 309269..309667 (-) 399 WP_004182034.1 cytidine deaminase -
  FOC73_RS01420 (FOC73_01420) deoC 309654..310316 (-) 663 WP_004182142.1 deoxyribose-phosphate aldolase -
  FOC73_RS01425 (FOC73_01425) - 310350..311627 (-) 1278 WP_002885171.1 pyrimidine-nucleoside phosphorylase -
  FOC73_RS01430 (FOC73_01430) - 311624..312214 (-) 591 WP_004182008.1 class I SAM-dependent methyltransferase -
  FOC73_RS01435 (FOC73_01435) coaA 312327..313247 (+) 921 WP_004182102.1 type I pantothenate kinase -
  FOC73_RS01440 (FOC73_01440) rpsT 313317..313553 (+) 237 WP_004182129.1 30S ribosomal protein S20 -
  FOC73_RS01445 (FOC73_01445) ciaH 313637..315052 (-) 1416 WP_037604990.1 cell wall metabolism sensor histidine kinase WalK Regulator
  FOC73_RS01450 (FOC73_01450) ciaR 315042..315716 (-) 675 WP_004182019.1 response regulator transcription factor Regulator
  FOC73_RS01455 (FOC73_01455) - 315915..317585 (-) 1671 WP_004182072.1 formate--tetrahydrofolate ligase -
  FOC73_RS01460 (FOC73_01460) - 317779..318462 (+) 684 WP_004182113.1 phosphopantothenate--cysteine ligase -
  FOC73_RS01465 (FOC73_01465) coaC 318455..319000 (+) 546 WP_004182014.1 phosphopantothenoylcysteine decarboxylase -
  FOC73_RS01470 (FOC73_01470) - 319029..319601 (+) 573 WP_004182105.1 ECF transporter S component -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53495.27 Da        Isoelectric Point: 8.7640

>NTDB_id=449918 FOC73_RS01445 WP_037604990.1 313637..315052(-) (ciaH) [Streptococcus salivarius strain FDAARGOS_771]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKESTAETPDSSGSKKEPKKKSKIEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVSRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRQLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=449918 FOC73_RS01445 WP_037604990.1 313637..315052(-) (ciaH) [Streptococcus salivarius strain FDAARGOS_771]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTTTTTGCTAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTACAGATTTTGAGTTACGGCGTTTATTCCAATGTGGATTCTA
GTCTGAAAATGGCAGCGACTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTGGATCAAAATAATACGACAACCATTTACCAAGCCTATGATACTAAAGAGTCAACAGCTGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAACCTAAGAAGAAATCAAAAATTGAAGATGCCCCTCACGATTTATCAGTTGCGGCAAATACCAGTGTCT
TGGTACTTGATAAGAATGGGAAAGTCCTCAATGTCGTTGATAAATTTTCAAGTTTATCTAATTTACCAATAGATAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACAGAAAAGTATCGTCTGATTACTGAAAAAGT
AGATAATAGTCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCTACTGAACGTT
ATGTTAAGCTCATTGTCATCATGATGAGTTTCTTCTGGCTCTTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAAAATGCTAGTCATGAGTTACGGACACCACTTGC
TGTGATTCAAAACAGATTAGAAGTTCTTTTCCGCAAGCCTGAGAGCACCATTCTAGATAATTCAGAGAATATTGCATCAA
GTCTTGATGAAGTACGTAATATGCGTCTTTTGACGACTAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTCTTTACCAATTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAACCAAGTTAGTCGTCCAATCCAAACTGATAAAACGCTATTGAAACAGTTAATGACCATCTTATTTG
ATAATGCTATTAAATATACGGAAGATGATGGACATGTTACCTTTACTGTTCGCACTAATGACCGCCAACTTTATATTTCT
GTAGCTGATAATGGTCCTGGGATATCAGATAGTGATAAGAAAAAAATCTTTGATCGATTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTTTAGCCCTAAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATCACTGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.739

97.665

0.554
  ciaH Streptococcus pneumoniae Rx1

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae D39

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae R6

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae TIGR4

50.216

98.514

0.495