Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   ST4021_RS07985 Genome accession   NZ_CP065493
Coordinates   1545207..1546010 (+) Length   267 a.a.
NCBI ID   WP_223899638.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4021     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1540207..1551010
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4021_RS07945 (ST4021_07980) - 1540389..1540781 (-) 393 WP_003094909.1 hypothetical protein -
  ST4021_RS07950 (ST4021_07985) cipB 1540793..1541032 (-) 240 WP_011681565.1 Blp family class II bacteriocin Regulator
  ST4021_RS07955 - 1541283..1541684 (-) 402 WP_011226490.1 hypothetical protein -
  ST4021_RS07960 (ST4021_07990) - 1542539..1542700 (-) 162 WP_011681568.1 hypothetical protein -
  ST4021_RS07965 (ST4021_07995) - 1542707..1542937 (-) 231 WP_011226494.1 bacteriocin class II family protein -
  ST4021_RS07970 (ST4021_08000) - 1543293..1543493 (-) 201 WP_011681569.1 hypothetical protein -
  ST4021_RS07975 (ST4021_08005) - 1543512..1543688 (-) 177 WP_011681570.1 Blp family class II bacteriocin -
  ST4021_RS07980 (ST4021_08010) - 1543939..1544676 (+) 738 WP_011681571.1 response regulator transcription factor -
  ST4021_RS07985 comD/blpH 1545207..1546010 (+) 804 WP_223899638.1 ATP-binding protein Regulator
  ST4021_RS07990 (ST4021_08020) - 1546028..1546189 (-) 162 WP_011681573.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  ST4021_RS07995 (ST4021_08025) comB 1546204..1547571 (-) 1368 WP_011681574.1 bacteriocin secretion accessory protein Regulator
  ST4021_RS08000 (ST4021_08030) comA/nlmT 1547587..1549740 (-) 2154 WP_041827772.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30641.92 Da        Isoelectric Point: 4.7379

>NTDB_id=449073 ST4021_RS07985 WP_223899638.1 1545207..1546010(+) (comD/blpH) [Streptococcus thermophilus strain 4021]
MYLENTTHSSTLELRKLCVVISLVLFFIMIVFLDRNIREMIQGQLDFQKNLQLENLYTYNKHIEGLYNSVRSFRHDYSNL
LVTLRLGIDKDDMDIVKEAYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
ETLDFIIVTSIFLDNAIEGAIQTQNPKITISFWEDHCSQLLSISNTISEEKTETKTIFERGVSNKGRERGIGLANVTEIL
DNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 804 bp        

>NTDB_id=449073 ST4021_RS07985 WP_223899638.1 1545207..1546010(+) (comD/blpH) [Streptococcus thermophilus strain 4021]
ATGTATCTTGAAAACACTACTCATTCTTCAACTTTGGAGCTTCGAAAACTCTGTGTTGTTATTTCACTTGTCCTCTTCTT
CATTATGATTGTCTTTTTAGACAGAAACATTCGTGAAATGATTCAAGGACAATTGGACTTCCAAAAAAATCTCCAGCTAG
AAAATCTCTACACCTACAATAAACATATTGAAGGTCTCTACAATTCTGTTCGTAGTTTTAGACACGATTATAGTAATCTC
TTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGTCAAAGAAGCCTATGATAGTGTGCTTCAAGAATC
CGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTAATATTCAGGATAACACTTTGAAAAGCCTTCTGT
CCGCAAAAGTTCTACAAGCAGAAGAAGAAGGCATTGAAGCTCAGATTAGCATCCCAGAACCCATCCACTTGATTGGGATG
GAGACTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGCTATTGAAGGTGCCATTCAAACTCAAAACCCTAA
AATTACTATTAGCTTTTGGGAAGATCATTGTTCACAGCTATTATCTATTAGCAATACCATAAGTGAAGAAAAAACAGAAA
CCAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGAGGCATTGGCCTTGCTAATGTCACAGAAATCTTA
GATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTCATTCACACAACAATTAACAATAACTAAAAAGGC
CTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(160-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.189

95.131

0.363