Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   ST4021_RS07995 Genome accession   NZ_CP065493
Coordinates   1546204..1547571 (-) Length   455 a.a.
NCBI ID   WP_011681574.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 4021     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1541204..1552571
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4021_RS07955 - 1541283..1541684 (-) 402 WP_011226490.1 hypothetical protein -
  ST4021_RS07960 (ST4021_07990) - 1542539..1542700 (-) 162 WP_011681568.1 hypothetical protein -
  ST4021_RS07965 (ST4021_07995) - 1542707..1542937 (-) 231 WP_011226494.1 bacteriocin class II family protein -
  ST4021_RS07970 (ST4021_08000) - 1543293..1543493 (-) 201 WP_011681569.1 hypothetical protein -
  ST4021_RS07975 (ST4021_08005) - 1543512..1543688 (-) 177 WP_011681570.1 Blp family class II bacteriocin -
  ST4021_RS07980 (ST4021_08010) - 1543939..1544676 (+) 738 WP_011681571.1 response regulator transcription factor -
  ST4021_RS07985 comD/blpH 1545207..1546010 (+) 804 WP_223899638.1 ATP-binding protein Regulator
  ST4021_RS07990 (ST4021_08020) - 1546028..1546189 (-) 162 WP_011681573.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  ST4021_RS07995 (ST4021_08025) comB 1546204..1547571 (-) 1368 WP_011681574.1 bacteriocin secretion accessory protein Regulator
  ST4021_RS08000 (ST4021_08030) comA/nlmT 1547587..1549740 (-) 2154 WP_041827772.1 peptide cleavage/export ABC transporter Regulator
  ST4021_RS08005 (ST4021_08035) - 1550754..1552499 (-) 1746 WP_011681577.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 455 a.a.        Molecular weight: 50382.07 Da        Isoelectric Point: 4.7492

>NTDB_id=449074 ST4021_RS07995 WP_011681574.1 1546204..1547571(-) (comB) [Streptococcus thermophilus strain 4021]
MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEVTVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKV
VKKGDTLVQYSETMEASQKEGLQKQLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGVAKT
NTEVNNQAAIASNTGSAIDNQISQLQTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQYATTPDASVTDQYLSQVN
TNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQFLQNAGQQLSSVETQINDTESKINQADVLLTNTLIQSPED
GILHLSQADKKATMAATGTELAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSAT
ETERGNVFRVTARASISEKEAQNLRYGLEGRVTSVIDQKTYFNYFKDKLLNLQDQ

Nucleotide


Download         Length: 1368 bp        

>NTDB_id=449074 ST4021_RS07995 WP_011681574.1 1546204..1547571(-) (comB) [Streptococcus thermophilus strain 4021]
ATGAATCCACAGTTGTTTAAAAGCACAGAGTTTTACCATCGTCGCTACCACAATATGTCTACTGTTTTGATTACTCCCTT
GATTTTGTTAGTTATTTTCCTTTTTCTTTTCGCTTTTTTTGCTAAGAAGGAAGTTACAGTCACGTCTAGAGGAAGTATAG
AGCCAACCAAGGTTATCGCAGTAATCCAATCAACCAGTGACAATACCATCATAGATAATCAACTGGTTGCTAATAAGGTT
GTTAAAAAAGGGGACACCTTAGTTCAGTATTCAGAGACCATGGAGGCATCGCAAAAAGAGGGGCTTCAAAAGCAACTAGA
ACTTTTAAAAAGACAGGAATCAGGTTTGAAGACCTTGCAATCTAGCCTAACGCAGGGAACCAATCTTTTCCAAGAACAGG
AAGACGAGTTTGGTTATCAGAGTACTTTTAACACCTACCTAAGTCAGGCACAGGATATTGACTTGGGTGTGGCTAAAACA
AATACAGAGGTTAATAACCAAGCAGCAATTGCGAGTAATACCGGTTCTGCTATTGATAACCAGATTAGTCAATTGCAGAC
TCAGGTCTCAGAGTATGAGGCGCTCTCTCAAGCTATTACCAATCATGAAACGACTTTACCTGAAGGCAATCCTCATCAGG
CAACCTTAAATGCCTATAACAGTCAGTATGCTACGACACCGGATGCCAGTGTAACAGACCAATACCTATCTCAAGTTAAT
ACCAATATTTCGAGCTTGAATGCTTCCATAGGTAATCTAGAAATCCAAAAGGCTGGGACAGGCACAGTTGTAACTTATGA
CAATAGTGATAGCACTAAAAAAGAAGCTCTAAAAAATCAATTCTTGCAAAATGCAGGACAGCAATTGAGCTCAGTGGAAA
CACAAATTAACGATACCGAGAGTAAAATCAATCAGGCAGATGTCCTTCTGACTAATACCCTCATCCAGTCACCAGAAGAT
GGAATCTTACACTTGAGTCAAGCTGATAAAAAAGCAACCATGGCTGCGACAGGAACTGAGTTGGCCCAGCTTTATCCCGA
TATGACTCAAACCCAGGAAGTTGCCATTACTTATTATGTGAATTCGGATTATGTGCCAAAACTGCAAAAAGGCCAGTCAG
TTCGACTGACCTTGGATAAGGTTGGTAATCACGGTACCACAATTATTGGAAAACTTGAGAGTATTGATAATTCTGCCACG
GAAACAGAAAGGGGGAATGTGTTTAGAGTAACTGCTAGGGCAAGTATTTCAGAAAAAGAAGCCCAAAATCTACGTTACGG
TCTAGAAGGTCGTGTGACAAGCGTTATTGACCAAAAGACCTACTTCAATTACTTTAAAGACAAGTTACTAAACTTGCAAG
ACCAATAG

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(315-427)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

39.468

99.121

0.391
  comB Streptococcus pneumoniae D39

39.468

99.121

0.391
  comB Streptococcus pneumoniae R6

39.468

99.121

0.391
  comB Streptococcus pneumoniae TIGR4

38.803

99.121

0.385
  comB Streptococcus mitis SK321

38.137

99.121

0.378
  comB Streptococcus mitis NCTC 12261

38.137

99.121

0.378