Detailed information NTG0448653

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: STCNRZ302_RS07430
• Genome accession: NZ_CP065489
• Coordinates: 1439815..1442055 (-)
• Length: 746 a.a.
• NCBI ID: WP_179970605.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CNRZ302
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1434815..1447055

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ302_RS07410 (STCNRZ302_07340)	-	1435679..1436539 (-)	861	WP_011226395.1	methionyl aminopeptidase	-
STCNRZ302_RS07415 (STCNRZ302_07345)	spxR	1436583..1437863 (-)	1281	WP_014608610.1	CBS-HotDog domain-containing transcription factor SpxR	-
STCNRZ302_RS07420 (STCNRZ302_07350)	-	1437856..1438401 (-)	546	WP_014608611.1	GNAT family N-acetyltransferase	-
STCNRZ302_RS07425 (STCNRZ302_07355)	-	1438467..1439729 (-)	1263	WP_014608612.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
STCNRZ302_RS07430 (STCNRZ302_07360)	comEC/celB	1439815..1442055 (-)	2241	WP_179970605.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
STCNRZ302_RS07435 (STCNRZ302_07365)	comEA	1442045..1442740 (-)	696	WP_014608614.1	helix-hairpin-helix domain-containing protein	Machinery gene
STCNRZ302_RS07440 (STCNRZ302_07370)	-	1442848..1443602 (-)	755	Protein_1412	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
STCNRZ302_RS07445	-	1443802..1444335 (+)	534	WP_014608615.1	polysaccharide deacetylase family protein	-
STCNRZ302_RS07450	-	1444432..1444593 (+)	162	WP_224102936.1	hypothetical protein	-
STCNRZ302_RS07455 (STCNRZ302_07380)	-	1444643..1445407 (+)	765	WP_014608617.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
STCNRZ302_RS07460 (STCNRZ302_07385)	-	1445411..1445680 (+)	270	WP_011226404.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84893.79 Da
• Isoelectric Point: 9.8901

>NTDB_id=448653 STCNRZ302_RS07430 WP_179970605.1 1439815..1442055(-) (comEC/celB) [Streptococcus thermophilus strain CNRZ302]
MWLKKAPINLFSLALLIVALYFTIFVSNFYAIGTFVFLVICFLRHHWKNRAALKLVGLIGGFFLVYFLFLYHIAIMQDKQ
TPAEIHQVTLVADTLSVNGERLSAIGKSNGQTYQVFYRLKSDREQHFFKTTSQTLVLKGKIKLSSATGQRNFQGFDYQSY
LASQGIYRIAQIERLEHAVTPKSISPIAFFHQLRRKALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKNYILAILLPFSIFYGLMTGWTASVLRSLIQSLLAECGIKKLNNMGITLLLFFLV
LPHFLLTVGGVLSCSYAFLLCLFNFEEMPSFKKSIYMSLVLSLGTLPFLTYYYGTFQPLSLILTAIFSLVFDSFLLPVLT
VLFTLSGMVIFSQFNTLFEWMEFFLTWVQSWGVQPLILGKPSLFQFVSMIFILVLLFDFWKKPQFRISLLMIFSLLMVWV
KHPLINEVTVVDVGQGDSIFLRSMKGETVLIDVGGKVTFGSKEKWQEGSQTSNAEKTLIPYLQARGVSQIDYLVLTHTDT
DHIGDLEVVAKRFKIKKICVSEGALTKPSFAKRIRFLKCPVRTLKAGDKLPMMGSNLQVLYPNKIGDGGNNDSLVLYGKL
LGTSFLFTGDLEKEGEEELMTSYPNLKVRVLKAGHHGSKDSSSEAFLDQLKPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQDGAIRFKGWFQLSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=448653 STCNRZ302_RS07430 WP_179970605.1 1439815..1442055(-) (comEC/celB) [Streptococcus thermophilus strain CNRZ302]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCCTAGCGCTTTTAATAGTTGCTCTTTATTTTACTATTTTTGTATC
TAATTTCTATGCTATTGGGACTTTTGTCTTTCTGGTGATATGTTTTTTGAGGCATCATTGGAAGAATAGAGCAGCTCTAA
AGTTGGTGGGACTTATAGGTGGTTTCTTTTTGGTCTACTTTTTATTTTTATACCATATAGCTATCATGCAAGATAAACAA
ACTCCTGCTGAAATTCATCAGGTGACACTGGTTGCAGATACGCTCTCAGTTAATGGTGAGCGATTATCAGCAATCGGGAA
GTCAAATGGACAAACCTATCAGGTCTTTTACCGGCTAAAATCTGATAGGGAGCAGCATTTTTTTAAGACTACTAGTCAAA
CGCTTGTTTTAAAAGGGAAAATAAAGTTGTCCTCGGCAACTGGTCAACGTAATTTTCAAGGCTTTGATTATCAGTCTTAT
CTAGCTAGTCAGGGCATTTATAGGATTGCTCAGATTGAGCGTCTGGAACATGCCGTAACCCCAAAATCGATATCTCCAAT
AGCTTTTTTTCATCAATTGAGGAGGAAGGCTCTAGTTCATATTCAGACGCATTTTCCTAATCCGATGAGACACTACATGA
CAGGACTACTCTTTGGGTATTTGGACAAGGAGTTTGATGAGCAGAGTCAACTCTACACTAGCTTGGGGATTATTCATCTT
TTTGCGCTATCGGGTATGCAGGTTGGATTTTTTCTTGGCTGGTTTCGCTATGGACTTCTCCGTTTGGGGCTTCCCAAAAA
TTATATCCTTGCTATCTTATTACCTTTTTCGATTTTCTATGGCTTAATGACTGGTTGGACGGCTTCGGTCTTACGTTCTT
TGATTCAAAGCCTCTTGGCTGAGTGTGGTATTAAAAAACTGAACAATATGGGCATAACGCTACTTCTATTTTTTCTAGTC
TTGCCTCATTTTCTTTTAACGGTAGGAGGTGTTTTAAGTTGTTCTTATGCCTTCTTGTTGTGTTTATTTAATTTTGAGGA
GATGCCGTCCTTTAAAAAGTCAATTTATATGAGTTTAGTATTGAGTCTTGGGACTTTGCCTTTTTTGACCTACTATTATG
GAACTTTTCAACCATTGAGTTTGATTCTGACGGCAATCTTCTCTCTAGTTTTTGATAGCTTTCTCTTACCTGTCTTAACA
GTACTTTTTACACTTTCAGGAATGGTAATTTTTTCTCAATTTAACACACTTTTTGAATGGATGGAGTTCTTTTTGACTTG
GGTACAATCTTGGGGGGTCCAGCCATTGATTTTAGGAAAACCTAGCTTGTTTCAGTTTGTCTCAATGATATTTATATTGG
TTTTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGAATATCCCTCTTGATGATTTTTAGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAATAAATGAAGTAACGGTGGTCGACGTTGGTCAAGGAGATAGTATTTTTTTAAGGAGTATGAAAGGTGA
AACGGTCCTAATAGATGTAGGTGGCAAGGTGACTTTCGGCTCTAAGGAAAAATGGCAAGAGGGGAGCCAGACGAGTAATG
CGGAGAAAACCTTAATTCCCTATCTACAGGCAAGGGGAGTGTCTCAAATTGACTATCTGGTTCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAGGTAGTGGCTAAACGGTTTAAGATTAAGAAAATTTGTGTCAGTGAGGGGGCTTTGACTAA
GCCTAGTTTTGCCAAACGTATTCGATTTCTTAAATGTCCCGTTCGCACTTTAAAGGCTGGTGATAAGCTGCCTATGATGG
GAAGTAACCTACAGGTTCTTTATCCCAATAAAATTGGTGATGGTGGTAACAATGATTCACTTGTTCTCTATGGAAAGTTA
TTGGGAACCAGTTTTCTATTTACTGGTGATTTGGAAAAAGAAGGAGAAGAGGAATTGATGACTAGCTATCCAAATTTAAA
AGTAAGGGTCCTCAAAGCAGGACATCACGGTTCTAAAGACTCTTCATCAGAAGCTTTTTTGGACCAGCTAAAGCCATCAC
TTGCTCTTGTCTCAGCAGGTGAAAATAATCGTTATAAGCATCCAAATGATGAAACATTAGAGCGTTTCAAAGAACGTCAC
ATTAAGGTTTTACGCACAGACCAGGATGGTGCCATTCGGTTTAAGGGATGGTTCCAACTATCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterProScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

• Competence protein (Competence) (216-462)

• Domain of unknown function (DUF4131) (DUF4131) (29-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	47.721	100	0.477
comEC/celB	Streptococcus mitis SK321	46.854	100	0.469
comEC/celB	Streptococcus pneumoniae TIGR4	45.917	100	0.46
comEC/celB	Streptococcus pneumoniae Rx1	45.649	100	0.457
comEC/celB	Streptococcus pneumoniae D39	45.649	100	0.457
comEC/celB	Streptococcus pneumoniae R6	45.649	100	0.457
comEC	Lactococcus lactis subsp. cremoris KW2	44.475	97.051	0.432