Detailed information NTG0448342

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: STR1_RS07385
• Genome accession: NZ_CP065486
• Coordinates: 1441296..1443536 (-)
• Length: 746 a.a.
• NCBI ID: WP_011681495.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain R1
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1436296..1448536

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STR1_RS07365 (STR1_07420)	-	1437160..1438020 (-)	861	WP_011226395.1	methionyl aminopeptidase	-
STR1_RS07370 (STR1_07425)	spxR	1438064..1439344 (-)	1281	WP_014608610.1	CBS-HotDog domain-containing transcription factor SpxR	-
STR1_RS07375 (STR1_07430)	-	1439337..1439882 (-)	546	WP_014608611.1	GNAT family N-acetyltransferase	-
STR1_RS07380 (STR1_07435)	-	1439948..1441210 (-)	1263	WP_095559426.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
STR1_RS07385 (STR1_07440)	comEC/celB	1441296..1443536 (-)	2241	WP_011681495.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
STR1_RS07390 (STR1_07445)	comEA	1443526..1444221 (-)	696	WP_023909867.1	helix-hairpin-helix domain-containing protein	Machinery gene
STR1_RS07395 (STR1_07450)	-	1444329..1445084 (-)	756	WP_011681497.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
STR1_RS07400 (STR1_07455)	-	1445284..1446150 (+)	867	WP_014621873.1	polysaccharide deacetylase family protein	-
STR1_RS07405 (STR1_07460)	-	1446200..1446964 (+)	765	WP_011681498.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
STR1_RS07410 (STR1_07465)	-	1446968..1447237 (+)	270	WP_011226404.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84759.76 Da
• Isoelectric Point: 9.9562

>NTDB_id=448342 STR1_RS07385 WP_011681495.1 1441296..1443536(-) (comEC/celB) [Streptococcus thermophilus strain R1]
MWLKKAPINLFSLALLIVALYFTIFVSNFYAIGTFVFLMICFLRHHWKNRAALKLVGLIGGFFLVYFLFLYHIAIMQDKQ
APAEIHQVTLVADTLSVNGERLSAIGKSNGQTYQVFYRLKSDKEQHFFKTTSQTLVLKGKIKLSSATGQRNFQGFDYQSY
LASQGIYRITQIERLEHVVTPKSISPIAFFHQLRRKALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKNYILAILLPFSIFYGLMTGWTASVLRSLIQSLLAECGIKKLNNMGITLLLFFLV
LPHFLLTVGGVLSCSYAFLLCLFNFEEMPSFKKSIYMSLVLSLGTLPFLTYYYGTSQPLSLILTAIFSLVFDSFLLPVLT
VLFTLSGMVIFSQFNPLFEWMEFFLTWVQSWGVQPLILGKPSLFQFVSMIFVLVLLFDFWKKPQFRISLLMIFSLLMVWV
KHPLINEVTVVDVGQGDSIFLRSMKGETVLIDVGGKVTFGSKKKWQEGSQTSNAEKTLIPYLQARGVSQIDYLVLTHTDT
DHIGDLEVVAKRFKIKKICVSEGALTKPSFAKRIRFLKCPVRTLKAGDKLPMMGSNLEVLYPNKIGDGGNNDSLVLYGKL
LGTSFLFTGDLEKEGEEELMASYPNLKVRVLKAGHHGSKGSSSEAFLDQLKPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQDGAIRFKGWFQLSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=448342 STR1_RS07385 WP_011681495.1 1441296..1443536(-) (comEC/celB) [Streptococcus thermophilus strain R1]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCCTAGCGCTTTTAATAGTTGCTCTTTATTTTACTATTTTTGTATC
TAATTTCTATGCTATTGGGACTTTTGTCTTTCTGATGATATGTTTTTTGAGGCATCATTGGAAGAATAGAGCAGCTCTAA
AGTTGGTGGGACTTATAGGTGGTTTCTTTTTGGTCTACTTTTTATTTTTATACCATATAGCTATCATGCAAGATAAACAA
GCTCCTGCTGAAATTCATCAGGTGACACTGGTTGCAGATACGCTCTCAGTTAATGGTGAGCGATTATCAGCAATCGGGAA
GTCAAATGGACAAACCTATCAGGTCTTTTACCGGCTAAAATCTGATAAGGAGCAGCATTTTTTTAAGACTACGAGTCAAA
CGCTTGTTTTAAAAGGGAAAATAAAGTTGTCCTCGGCAACTGGTCAACGTAATTTTCAAGGCTTTGATTATCAGTCTTAT
CTAGCTAGTCAGGGCATTTATAGGATTACTCAGATTGAGCGTCTGGAACATGTCGTAACCCCAAAATCGATATCTCCAAT
AGCTTTTTTTCATCAATTGAGGAGGAAGGCTCTAGTTCATATTCAGACGCATTTTCCTAATCCGATGAGACACTACATGA
CAGGACTGCTCTTTGGGTATTTGGACAAGGAGTTTGATGAGCAGAGTCAACTCTACACTAGCTTGGGGATTATTCATCTT
TTTGCGCTATCGGGTATGCAGGTTGGATTTTTTCTTGGCTGGTTTCGCTATGGACTTCTCCGTTTGGGGCTTCCCAAAAA
TTATATCCTTGCTATCTTATTACCTTTTTCGATTTTCTATGGCTTAATGACTGGTTGGACGGCTTCAGTCTTACGTTCTT
TGATTCAAAGCCTCTTGGCTGAGTGTGGTATTAAAAAACTGAACAATATGGGCATAACGCTACTTCTATTTTTTCTAGTC
TTGCCTCATTTTCTTTTAACGGTAGGAGGTGTTTTAAGTTGTTCTTATGCCTTCTTGTTGTGTTTATTTAATTTTGAGGA
GATGCCGTCCTTTAAAAAGTCAATTTATATGAGTTTAGTATTGAGTCTTGGGACTTTGCCTTTTTTGACCTACTATTATG
GAACTTCTCAACCATTGAGTTTGATTCTGACGGCAATCTTCTCTCTAGTTTTTGATAGCTTTCTCTTACCTGTCTTAACA
GTACTTTTTACACTTTCAGGAATGGTAATTTTTTCTCAATTTAATCCACTTTTTGAATGGATGGAGTTCTTTTTGACTTG
GGTACAATCTTGGGGAGTCCAGCCATTGATTTTAGGAAAACCTAGCTTGTTTCAGTTTGTCTCAATGATATTTGTATTGG
TTTTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGAATATCCCTCTTGATGATTTTTAGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAATAAATGAAGTAACGGTGGTCGACGTTGGTCAAGGAGATAGTATTTTTTTAAGGAGTATGAAAGGTGA
GACGGTCCTAATAGATGTAGGTGGCAAGGTGACTTTCGGCTCTAAGAAAAAATGGCAAGAGGGGAGCCAGACGAGTAATG
CGGAGAAAACCTTAATTCCCTATCTACAGGCAAGGGGAGTGTCTCAAATTGACTATCTGGTTCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAGGTAGTGGCTAAACGGTTTAAGATTAAGAAAATTTGTGTCAGTGAGGGGGCTTTGACTAA
GCCTAGTTTTGCCAAACGTATTCGATTTCTTAAATGTCCCGTTCGCACTTTAAAGGCTGGTGATAAGCTGCCTATGATGG
GAAGTAACCTAGAGGTTCTTTATCCCAATAAAATTGGTGATGGTGGTAACAATGATTCACTTGTTCTCTATGGAAAGTTA
TTGGGAACCAGTTTTCTGTTTACTGGTGATTTGGAAAAAGAAGGAGAAGAGGAATTGATGGCTAGCTATCCAAATTTAAA
AGTAAGGGTCCTCAAAGCAGGACATCACGGTTCTAAAGGCTCTTCATCAGAAGCTTTTTTGGACCAGCTAAAGCCATCAC
TTGCTCTTGTCTCAGCAGGTGAAAATAATCGTTATAAGCATCCAAATGATGAAACATTAGAGCGTTTCAAAGAACGTCAC
ATTAAGGTTTTACGCACAGACCAGGATGGTGCCATTCGGTTTAAGGGATGGTTCCAACTATCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterProScan.

• Competence protein (Competence) (216-462)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	47.587	100	0.476
comEC/celB	Streptococcus mitis SK321	46.72	100	0.468
comEC/celB	Streptococcus pneumoniae TIGR4	46.051	100	0.461
comEC/celB	Streptococcus pneumoniae D39	45.783	100	0.458
comEC/celB	Streptococcus pneumoniae Rx1	45.783	100	0.458
comEC/celB	Streptococcus pneumoniae R6	45.783	100	0.458
comEC	Lactococcus lactis subsp. cremoris KW2	44.966	97.185	0.437