Detailed information NTG0448028

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: STCNRZ1151_RS07260
• Genome accession: NZ_CP065483
• Coordinates: 1382866..1385106 (-)
• Length: 746 a.a.
• NCBI ID: WP_011227470.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CNRZ1151
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1377866..1390106

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STCNRZ1151_RS07240 (STCNRZ1151_07240)	-	1378730..1379590 (-)	861	WP_011227466.1	methionyl aminopeptidase	-
STCNRZ1151_RS07245 (STCNRZ1151_07245)	spxR	1379634..1380914 (-)	1281	WP_011227467.1	CBS-HotDog domain-containing transcription factor SpxR	-
STCNRZ1151_RS07250 (STCNRZ1151_07250)	-	1380907..1381452 (-)	546	WP_022096992.1	GNAT family N-acetyltransferase	-
STCNRZ1151_RS07255 (STCNRZ1151_07255)	-	1381518..1382780 (-)	1263	WP_041827084.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
STCNRZ1151_RS07260 (STCNRZ1151_07260)	comEC/celB	1382866..1385106 (-)	2241	WP_011227470.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
STCNRZ1151_RS07265 (STCNRZ1151_07265)	comEA	1385096..1385791 (-)	696	WP_011226400.1	helix-hairpin-helix domain-containing protein	Machinery gene
STCNRZ1151_RS07270 (STCNRZ1151_07270)	-	1385899..1386654 (-)	756	WP_002948862.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
STCNRZ1151_RS07275	-	1386854..1387387 (+)	534	WP_011226401.1	polysaccharide deacetylase family protein	-
STCNRZ1151_RS07280	-	1387321..1387719 (+)	399	WP_288576965.1	peptidoglycan GlcNAc deacetylase	-
STCNRZ1151_RS07285 (STCNRZ1151_07280)	-	1387769..1388533 (+)	765	WP_011226403.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
STCNRZ1151_RS07290 (STCNRZ1151_07285)	-	1388537..1388806 (+)	270	WP_011226404.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84850.87 Da
• Isoelectric Point: 9.9608

>NTDB_id=448028 STCNRZ1151_RS07260 WP_011227470.1 1382866..1385106(-) (comEC/celB) [Streptococcus thermophilus strain CNRZ1151]
MWLKKAPINLFSLALLIVALYFTIFVSNFYAIGTFVFLMICFLRHHWKNRAALKLVGLIGGFFLVYFLFLYHIAIMQDKQ
TPAEIHQVTLVADTLSVNGERLSAIGKSNGQTYQVFYRLKSDKEQHFFKTTSQTLVLKGKIKLSSATGQRNFQGFDYQSY
LASQGIYRIAQIDRLEHVVIPKSISPIAFFHQLRRKALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKNYILAILLPFSIFYGLMTGWTASVLRSLIQSLLAECGIKKLNNMGITLLLFFLV
LPHFLLTVGGVLSCSYAFLLCLFNFEEMPSFKKSIYMSLVLSLGTLPFLTYYYGTFQPLSLILTAIFSLVFDSFLLPVLT
VLFTLSGMVIFSQFNTLFEWMEFFLTWVQSWGVQPLILGKPSLFQFVSMIFVLVLLFDFWKKPQFRISLLMIFSLLMVWV
KHPLINEVTVVDVGQGDSIFLRSMKGETVLIDVGGKVTFGSKEKWQEGSQTSNAEKTLIPYLQARGVSQIDYLVLTHTDT
DHIGDLEVVAKRFKIKKICVSEGALTKPSFAKRIRFLKCPVRTLKAGDKLPMMGSNLQVLYPNKIGNGGNNDSLVLYGKL
LGTSFLFTGDLEKEGEEELMTSYPNLKVRVLKAGHHGSKGSSSEAFLDQLKPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQDGAIRFKGWFQLSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=448028 STCNRZ1151_RS07260 WP_011227470.1 1382866..1385106(-) (comEC/celB) [Streptococcus thermophilus strain CNRZ1151]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCCTAGCGCTTTTAATAGTTGCTCTTTATTTTACTATTTTTGTATC
TAATTTCTATGCTATTGGGACTTTTGTCTTTCTGATGATATGTTTTTTGAGGCATCATTGGAAGAATAGAGCAGCTCTAA
AGTTGGTGGGACTTATAGGTGGTTTCTTTTTGGTCTACTTTTTATTTTTATACCATATAGCTATCATGCAAGATAAACAA
ACTCCTGCTGAAATTCATCAGGTGACACTGGTTGCAGATACGCTCTCAGTTAATGGTGAGCGATTATCAGCAATCGGGAA
GTCAAATGGACAAACCTATCAGGTCTTTTACCGGCTAAAATCTGATAAGGAGCAGCATTTTTTTAAGACTACTAGTCAAA
CGCTTGTTTTAAAAGGGAAAATAAAGTTGTCCTCGGCAACTGGTCAACGTAATTTTCAAGGATTTGATTATCAGTCTTAT
CTAGCTAGTCAGGGCATTTATAGGATTGCTCAGATTGACCGTCTGGAACATGTCGTAATCCCAAAATCGATATCTCCAAT
AGCTTTTTTTCATCAATTGAGGAGGAAGGCTCTAGTTCATATTCAGACGCATTTTCCTAATCCGATGAGACACTACATGA
CAGGACTGCTCTTTGGGTATTTGGACAAGGAGTTTGATGAGCAGAGTCAACTCTACACTAGCTTGGGGATTATTCATCTT
TTTGCGCTATCGGGTATGCAGGTTGGATTTTTTCTTGGCTGGTTTCGCTATGGACTTCTCCGTTTGGGGCTTCCCAAAAA
TTATATCCTTGCTATCTTATTACCTTTTTCGATTTTCTATGGCTTAATGACTGGTTGGACGGCTTCGGTCTTACGTTCTT
TGATTCAAAGCCTCTTGGCTGAGTGTGGTATTAAAAAACTGAACAATATGGGCATAACGCTACTTCTATTTTTTCTAGTC
TTGCCTCATTTTCTTTTAACGGTAGGAGGTGTTTTAAGTTGTTCTTATGCCTTCTTGTTGTGTTTATTTAATTTTGAGGA
GATGCCGTCCTTTAAAAAGTCAATTTATATGAGTTTAGTATTGAGTCTTGGGACTTTGCCTTTTTTGACCTACTATTATG
GAACTTTTCAACCATTGAGTTTGATTCTGACGGCAATCTTCTCTCTAGTTTTTGATAGCTTTCTCTTACCTGTCTTAACA
GTACTTTTTACACTTTCAGGAATGGTAATTTTTTCTCAATTTAACACACTTTTTGAATGGATGGAGTTCTTTTTGACTTG
GGTACAATCTTGGGGAGTCCAGCCATTGATTTTAGGAAAACCTAGCTTGTTTCAGTTTGTCTCAATGATATTTGTATTGG
TTTTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGAATATCCCTCTTGATGATTTTTAGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAATAAATGAAGTAACGGTGGTCGACGTTGGTCAAGGAGATAGTATTTTTTTAAGGAGTATGAAAGGTGA
AACGGTCCTAATAGATGTAGGTGGCAAGGTGACTTTCGGCTCTAAGGAAAAATGGCAAGAGGGGAGCCAGACGAGTAATG
CGGAGAAAACCTTAATTCCCTATCTACAGGCAAGGGGAGTGTCTCAAATTGACTATCTGGTTCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAGGTAGTGGCTAAACGGTTTAAGATTAAGAAAATTTGTGTCAGTGAGGGGGCTTTGACTAA
GCCTAGTTTTGCCAAACGTATTCGATTTCTTAAATGTCCCGTTCGCACTTTAAAGGCTGGTGATAAGCTGCCTATGATGG
GAAGTAACCTACAGGTTCTTTATCCCAATAAAATTGGTAATGGTGGTAACAATGATTCACTTGTTCTCTATGGAAAGTTA
TTGGGAACCAGTTTTCTATTTACTGGTGATTTGGAAAAAGAAGGAGAAGAGGAATTGATGACTAGCTATCCAAATTTAAA
AGTAAGGGTCCTCAAAGCAGGACATCACGGTTCTAAAGGCTCTTCATCAGAAGCTTTTTTGGATCAGCTAAAGCCATCAC
TTGCTCTTGTCTCAGCAGGTGAAAATAATCGTTATAAGCATCCAAATGATGAAACATTAGAGCGTTTCAAAGAACGTCAC
ATTAAGGTTTTACGCACAGACCAGGATGGTGCCATTCGGTTTAAGGGATGGTTCCAACTATCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterProScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

• Competence protein (Competence) (216-462)

• Domain of unknown function (DUF4131) (DUF4131) (29-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	47.587	100	0.476
comEC/celB	Streptococcus mitis SK321	46.72	100	0.468
comEC/celB	Streptococcus pneumoniae TIGR4	45.783	100	0.458
comEC/celB	Streptococcus pneumoniae D39	45.515	100	0.456
comEC/celB	Streptococcus pneumoniae Rx1	45.515	100	0.456
comEC/celB	Streptococcus pneumoniae R6	45.515	100	0.456
comEC	Lactococcus lactis subsp. cremoris KW2	45.379	97.185	0.441